| Endothelial cell migration during angiogenesis L Lamalice, F Le Boeuf, J Huot Circulation research 100 (6), 782-794, 2007 | 1735 | 2007 |
| Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans CJ Breitbach, J Burke, D Jonker, J Stephenson, AR Haas, LQM Chow, ... Nature 477 (7362), 99-102, 2011 | 624 | 2011 |
| The oncolytic poxvirus JX-594 selectively replicates in and destroys cancer cells driven by genetic pathways commonly activated in cancers KA Parato, CJ Breitbach, F Le Boeuf, J Wang, C Storbeck, C Ilkow, ... Molecular Therapy 20 (4), 749-758, 2012 | 325 | 2012 |
| Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus DH Kirn, Y Wang, F Le Boeuf, J Bell, SH Thorne PLoS medicine 4 (12), e353, 2007 | 250 | 2007 |
| Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities F Le Boeuf, F Houle, J Huot Journal of Biological Chemistry 279 (37), 39175-39185, 2004 | 178 | 2004 |
| Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase M Duval, F Le Bœuf, J Huot, JP Gratton Molecular biology of the cell 18 (11), 4659-4668, 2007 | 173 | 2007 |
| Synergistic interaction between oncolytic viruses augments tumor killing F Le Boeuf, JS Diallo, JA McCart, S Thorne, T Falls, M Stanford, F Kanji, ... Molecular Therapy 18 (5), 888-895, 2010 | 154 | 2010 |
| Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity CS Ilkow, M Marguerie, C Batenchuk, J Mayer, D Ben Neriah, ... Nature medicine 21 (5), 530-536, 2015 | 153 | 2015 |
| Smac mimetics and innate immune stimuli synergize to promote tumor death ST Beug, VA Tang, EC LaCasse, HH Cheung, CE Beauregard, J Brun, ... Nature biotechnology 32 (2), 182-190, 2014 | 144 | 2014 |
| Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine CG Lemay, JL Rintoul, A Kus, JM Paterson, V Garcia, TJ Falls, L Ferreira, ... Molecular Therapy 20 (9), 1791-1799, 2012 | 121 | 2012 |
| A high-throughput pharmacoviral approach identifies novel oncolytic virus sensitizers JS Diallo, F Le Boeuf, F Lai, J Cox, M Vaha-Koskela, H Abdelbary, ... Molecular Therapy 18 (6), 1123-1129, 2010 | 112 | 2010 |
| VEGF-mediated induction of PRD1-BF1/Blimp1 expression sensitizes tumor vasculature to oncolytic virus infection R Arulanandam, C Batenchuk, FA Angarita, K Ottolino-Perry, ... Cancer Cell 28 (2), 210-224, 2015 | 107 | 2015 |
| Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2–mediated phosphorylation of FAK … F Le Boeuf, F Houle, M Sussman, J Huot Molecular biology of the cell 17 (8), 3508-3520, 2006 | 89 | 2006 |
| Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors H MacTavish, JS Diallo, B Huang, M Stanford, F Le Boeuf, N De Silva, ... PLoS One 5 (12), e14462, 2010 | 85 | 2010 |
| Multi-modal potentiation of oncolytic virotherapy by vanadium compounds M Selman, C Rousso, A Bergeron, HH Son, R Krishnan, NA El-Sayes, ... Molecular Therapy 26 (1), 56-69, 2018 | 83 | 2018 |
| RhoA activation mediates phosphatidylinositol 3-kinase–dependent proliferation of human vascular endothelial cells: an alloimmune mechanism of chronic allograft nephropathy F Leboeuf, JP Soulillou Journal of the American Society of Nephrology 15 (9), 2429-2439, 2004 | 75 | 2004 |
| Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors JG Pol, S Levesque, ST Workenhe, S Gujar, F Le Boeuf, DR Clements, ... Oncoimmunology 7 (12), e1503032, 2018 | 73 | 2018 |
| Antiangiogenic arming of an oncolytic vaccinia virus enhances antitumor efficacy in renal cell cancer models K Guse, M Sloniecka, I Diaconu, K Ottolino-Perry, N Tang, C Ng, ... Journal of virology 84 (2), 856-866, 2010 | 72 | 2010 |
| Propagation, purification, and in vivo testing of oncolytic vesicular stomatitis virus strains JS Diallo, M Vähä-Koskela, F Le Boeuf, J Bell Oncolytic Viruses: Methods and Protocols, 127-140, 2012 | 66 | 2012 |
| Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing R Arulanandam, C Batenchuk, O Varette, C Zakaria, V Garcia, NE Forbes, ... Nature communications 6 (1), 6410, 2015 | 60 | 2015 |
Jacques HuotProfesseur Émérite- Faculté de médecine de l'Université LavalVerified email at fmed.ulaval.ca
