Adrian Serohijos
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Phenylalanine-508 mediates a cytoplasmic–membrane domain contact in the CFTR 3D structure crucial to assembly and channel function
AWR Serohijos, T Hegedűs, AA Aleksandrov, L He, L Cui, NV Dokholyan, ...
Proceedings of the National Academy of Sciences 105 (9), 3256-3261, 2008
Protein quality control acts on folding intermediates to shape the effects of mutations on organismal fitness
S Bershtein, W Mu, AWR Serohijos, J Zhou, EI Shakhnovich
Molecular cell 49 (1), 133-144, 2013
Protein folding: then and now
Y Chen, F Ding, H Nie, AW Serohijos, S Sharma, KC Wilcox, S Yin, ...
Archives of biochemistry and biophysics 469 (1), 4-19, 2008
Multiple membrane-cytoplasmic domain contacts in the cystic fibrosis transmembrane conductance regulator (CFTR) mediate regulation of channel gating
L He, AA Aleksandrov, AWR Serohijos, T Hegedüs, LA Aleksandrov, ...
Journal of Biological Chemistry 283 (39), 26383-26390, 2008
Protein biophysics explains why highly abundant proteins evolve slowly
AWR Serohijos, Z Rimas, EI Shakhnovich
Cell reports 2 (2), 249-256, 2012
Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics
AWR Serohijos, EI Shakhnovich
Current opinion in structural biology 26, 84-91, 2014
Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR
T Hegedűs, AWR Serohijos, NV Dokholyan, L He, JR Riordan
Journal of molecular biology 378 (5), 1052-1063, 2008
Identification and rational redesign of peptide ligands to CRIP1, a novel biomarker for cancers
J Hao, AWR Serohijos, G Newton, G Tassone, Z Wang, DC Sgroi, ...
PLoS Comput Biol 4 (8), e1000138, 2008
Protein homeostasis imposes a barrier on functional integration of horizontally transferred genes in bacteria
S Bershtein, AWR Serohijos, S Bhattacharyya, M Manhart, JM Choi, W Mu, ...
PLoS Genet 11 (10), e1005612, 2015
Diminished self-chaperoning activity of the ΔF508 mutant of CFTR results in protein misfolding
AWR Serohijos, T Hegedűs, JR Riordan, NV Dokholyan
PLoS Comput Biol 4 (2), e1000008, 2008
Bridging the physical scales in evolutionary biology: from protein sequence space to fitness of organisms and populations
S Bershtein, AWR Serohijos, EI Shakhnovich
Current opinion in structural biology 42, 31-40, 2017
Positively selected sites in cetacean myoglobins contribute to protein stability
P Dasmeh, AWR Serohijos, KP Kepp, EI Shakhnovich
PLoS Comput Biol 9 (3), e1002929, 2013
Contribution of selection for protein folding stability in shaping the patterns of polymorphisms in coding regions
AWR Serohijos, EI Shakhnovich
Molecular biology and evolution 31 (1), 165-176, 2014
Influenza A H1N1 pandemic strain evolution–divergence and the potential for antigenic drift variants
EY Klein, AWR Serohijos, JM Choi, EI Shakhnovich, A Pekosz
PloS one 9 (4), e93632, 2014
A structural model reveals energy transduction in dynein
AWR Serohijos, Y Chen, F Ding, TC Elston, NV Dokholyan
Proceedings of the National Academy of Sciences 103 (49), 18540-18545, 2006
The Influence of Selection for Protein Stability on dN/dS Estimations
P Dasmeh, AWR Serohijos, KP Kepp, EI Shakhnovich
Genome biology and evolution 6 (10), 2956-2967, 2014
A structural model of the pore-forming region of the skeletal muscle ryanodine receptor (RyR1)
S Ramachandran, AWR Serohijos, L Xu, G Meissner, NV Dokholyan
PLoS Comput Biol 5 (4), e1000367, 2009
Kinetic models for the coordinated stepping of cytoplasmic dynein
D Tsygankov, AWR Serohijos, NV Dokholyan, TC Elston
The Journal of chemical physics 130 (2), 01B605, 2009
Highly abundant proteins favor more stable 3D structures in yeast
AWR Serohijos, SYR Lee, EI Shakhnovich
Biophysical journal 104 (3), L1-L3, 2013
Isolation and analysis of rare norovirus recombinants from coinfected mice using drop-based microfluidics
H Zhang, SK Cockrell, AO Kolawole, A Rotem, AWR Serohijos, CB Chang, ...
Journal of virology 89 (15), 7722-7734, 2015
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Articles 1–20