Traumatic brain injury causes chronic cortical inflammation and neuronal dysfunction mediated by microglia KG Witcher, CE Bray, T Chunchai, F Zhao, SM O'Neil, AJ Gordillo, ... Journal of Neuroscience 41 (7), 1597-1616, 2021 | 207 | 2021 |
Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge SM O’Neil, KG Witcher, DB McKim, JP Godbout Acta neuropathologica communications 6, 1-20, 2018 | 120 | 2018 |
Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress DJ DiSabato, DP Nemeth, X Liu, KG Witcher, SM O’Neil, B Oliver, CE Bray, ... Molecular Psychiatry 26 (9), 4770-4782, 2021 | 61 | 2021 |
Sleep disruption exacerbates and prolongs the inflammatory response to traumatic brain injury ZM Tapp, JE Kumar, KG Witcher, RR Atluri, JA Velasquez, SM O'Neil, ... Journal of neurotrauma 37 (16), 1829-1843, 2020 | 35 | 2020 |
Astrocyte immunosenescence and deficits in interleukin 10 signaling in the aged brain disrupt the regulation of microglia following innate immune activation SM O'Neil, EE Hans, S Jiang, LM Wangler, JP Godbout Glia 70 (5), 913-934, 2022 | 29 | 2022 |
Chronic cortical inflammation, cognitive impairment, and immune reactivity associated with diffuse brain injury are ameliorated by forced turnover of microglia CE Bray, KG Witcher, D Adekunle-Adegbite, M Ouvina, M Witzel, E Hans, ... Journal of Neuroscience 42 (20), 4215-4228, 2022 | 28 | 2022 |
Amplified gliosis and interferon-associated inflammation in the aging brain following diffuse traumatic brain injury LM Wangler, CE Bray, JM Packer, ZM Tapp, AC Davis, SM O'Neil, K Baetz, ... Journal of Neuroscience 42 (48), 9082-9096, 2022 | 24 | 2022 |
Prolonged STAT1 activation in neurons drives a pathological transcriptional response DN Clark, SM O'Neil, L Xu, JT Steppe, JT Savage, K Raghunathan, ... Journal of Neuroimmunology 382, 578168, 2023 | 3 | 2023 |
Improving thymus implantation for congenital athymia with interleukin‐7 H Min, LA Valente, L Xu, SM O'Neil, LR Begg, J Kurtzberg, AJ Filiano Clinical & translational immunology 12 (11), e1475, 2023 | 1 | 2023 |
Abstract 5 Human Umbilical Cord Blood-Derived Cell Therapy Product, DUOC-01, Promotes Remyelination by Driving the Differentiation of Oligodendrocyte Progenitor Cells L Xu, A Saha, R Parrott, S O’Neil, J Kurtzberg, A Filiano Stem Cells Translational Medicine 11 (Supplement_1), S7-S7, 2022 | 1 | 2022 |
Hematopoietic stem/progenitor cells and engineering: human umbilical cord blood derived cell therapy product, DUOC-01, promotes remyelination by driving the differentiation of OPC L Xu, A Saha, R Parrott, S O’Neil, J Kurtzberg, AJ Filiano Cytotherapy 24 (5), S26, 2022 | 1 | 2022 |
Mural cells interact with macrophages in the dura mater to regulate CNS immune surveillance H Min, SM O’Neil, L Xu, EA Moseman, J Kurtzberg, AJ Filiano Journal of Experimental Medicine 221 (2), e20230326, 2024 | | 2024 |
Abstract 30 Cord Blood Derived Macrophages Promote Remyelination L Xu, S O'Neil, J Kurtzberg, A Filiano Stem Cells Translational Medicine 12 (Supplement_1), S32-S32, 2023 | | 2023 |
Hematopoietic Stem/Progenitor Cells and Engineering: CORD BLOOD DERIVED MACROPHAGES RELEASE FACTORS TO PROMOTE REMYELINATION L Xu, A Saha, RE Parrott, S O’Neil, J Kurtzberg, AJ Filiano Cytotherapy 25 (6), S137, 2023 | | 2023 |
CHRONIC CORTICAL INFLAMMATION, COGNITIVE IMPAIRMENT AND IMMUNE REACTIVITY ASSOCIATED WITH DIFFUSE BRAIN INJURY ARE AMELIORATED BY FORCED TURNOVER OF MICROGLIA J Godbout, C Bray, K Witcher, D Adekunle-Adegbite, M Ouvina, M Witzel, ... JOURNAL OF NEUROTRAUMA 39 (11-12), A72-A73, 2022 | | 2022 |
AMPLIFIED GLIOSIS AND INTERFERON-ASSOCIATED INFLAMMATION IN AGED MICE FOLLOWING TRAUMATIC BRAIN INJURY L Wangler, C Bray, J Packer, Z Tapp, A Davis, S O'Neil, J Godbout JOURNAL OF NEUROTRAUMA 39 (11-12), A3-A4, 2022 | | 2022 |
HUMAN UMBILICAL CORD BLOOD DERIVED CELL THERAPY PRODUCT, DUOC-01, PROMOTES REMYELINATION BY DRIVING THE DIFFERENTIATION OF OPC L Xu, A Saha, R Parrott, S O'Neil, J Kurtzberg, AJ Filiano CYTOTHERAPY 24 (5), S26-S26, 2022 | | 2022 |
Astrocyte immunosenescence in IL-10 and cholesterol signaling in the aged brain impairs microglial regulation following peripheral immune activation SM O'Neil, EE Hans, S Jiang, LM Wangler, JP Godbout Brain, Behavior, and Immunity 98, 37, 2021 | | 2021 |
Correction: Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress. DJ DiSabato, DP Nemeth, X Liu, KG Witcher, SM O'Neil, B Oliver, CE Bray, ... Molecular Psychiatry 26 (9), 4783-4783, 2021 | | 2021 |
How Dysfunctional Microglia/Astrocyte Signaling Leads to Age-Associated Neuroinflammation and Cognitive Impairment SM O'Neil The Ohio State University, 2021 | | 2021 |