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Shane O'Neil
Shane O'Neil
Verified email at duke.edu
Title
Cited by
Cited by
Year
Traumatic brain injury causes chronic cortical inflammation and neuronal dysfunction mediated by microglia
KG Witcher, CE Bray, T Chunchai, F Zhao, SM O'Neil, AJ Gordillo, ...
Journal of Neuroscience 41 (7), 1597-1616, 2021
2072021
Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge
SM O’Neil, KG Witcher, DB McKim, JP Godbout
Acta neuropathologica communications 6, 1-20, 2018
1202018
Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress
DJ DiSabato, DP Nemeth, X Liu, KG Witcher, SM O’Neil, B Oliver, CE Bray, ...
Molecular Psychiatry 26 (9), 4770-4782, 2021
612021
Sleep disruption exacerbates and prolongs the inflammatory response to traumatic brain injury
ZM Tapp, JE Kumar, KG Witcher, RR Atluri, JA Velasquez, SM O'Neil, ...
Journal of neurotrauma 37 (16), 1829-1843, 2020
352020
Astrocyte immunosenescence and deficits in interleukin 10 signaling in the aged brain disrupt the regulation of microglia following innate immune activation
SM O'Neil, EE Hans, S Jiang, LM Wangler, JP Godbout
Glia 70 (5), 913-934, 2022
292022
Chronic cortical inflammation, cognitive impairment, and immune reactivity associated with diffuse brain injury are ameliorated by forced turnover of microglia
CE Bray, KG Witcher, D Adekunle-Adegbite, M Ouvina, M Witzel, E Hans, ...
Journal of Neuroscience 42 (20), 4215-4228, 2022
282022
Amplified gliosis and interferon-associated inflammation in the aging brain following diffuse traumatic brain injury
LM Wangler, CE Bray, JM Packer, ZM Tapp, AC Davis, SM O'Neil, K Baetz, ...
Journal of Neuroscience 42 (48), 9082-9096, 2022
242022
Prolonged STAT1 activation in neurons drives a pathological transcriptional response
DN Clark, SM O'Neil, L Xu, JT Steppe, JT Savage, K Raghunathan, ...
Journal of Neuroimmunology 382, 578168, 2023
32023
Improving thymus implantation for congenital athymia with interleukin‐7
H Min, LA Valente, L Xu, SM O'Neil, LR Begg, J Kurtzberg, AJ Filiano
Clinical & translational immunology 12 (11), e1475, 2023
12023
Abstract 5 Human Umbilical Cord Blood-Derived Cell Therapy Product, DUOC-01, Promotes Remyelination by Driving the Differentiation of Oligodendrocyte Progenitor Cells
L Xu, A Saha, R Parrott, S O’Neil, J Kurtzberg, A Filiano
Stem Cells Translational Medicine 11 (Supplement_1), S7-S7, 2022
12022
Hematopoietic stem/progenitor cells and engineering: human umbilical cord blood derived cell therapy product, DUOC-01, promotes remyelination by driving the differentiation of OPC
L Xu, A Saha, R Parrott, S O’Neil, J Kurtzberg, AJ Filiano
Cytotherapy 24 (5), S26, 2022
12022
Mural cells interact with macrophages in the dura mater to regulate CNS immune surveillance
H Min, SM O’Neil, L Xu, EA Moseman, J Kurtzberg, AJ Filiano
Journal of Experimental Medicine 221 (2), e20230326, 2024
2024
Abstract 30 Cord Blood Derived Macrophages Promote Remyelination
L Xu, S O'Neil, J Kurtzberg, A Filiano
Stem Cells Translational Medicine 12 (Supplement_1), S32-S32, 2023
2023
Hematopoietic Stem/Progenitor Cells and Engineering: CORD BLOOD DERIVED MACROPHAGES RELEASE FACTORS TO PROMOTE REMYELINATION
L Xu, A Saha, RE Parrott, S O’Neil, J Kurtzberg, AJ Filiano
Cytotherapy 25 (6), S137, 2023
2023
CHRONIC CORTICAL INFLAMMATION, COGNITIVE IMPAIRMENT AND IMMUNE REACTIVITY ASSOCIATED WITH DIFFUSE BRAIN INJURY ARE AMELIORATED BY FORCED TURNOVER OF MICROGLIA
J Godbout, C Bray, K Witcher, D Adekunle-Adegbite, M Ouvina, M Witzel, ...
JOURNAL OF NEUROTRAUMA 39 (11-12), A72-A73, 2022
2022
AMPLIFIED GLIOSIS AND INTERFERON-ASSOCIATED INFLAMMATION IN AGED MICE FOLLOWING TRAUMATIC BRAIN INJURY
L Wangler, C Bray, J Packer, Z Tapp, A Davis, S O'Neil, J Godbout
JOURNAL OF NEUROTRAUMA 39 (11-12), A3-A4, 2022
2022
HUMAN UMBILICAL CORD BLOOD DERIVED CELL THERAPY PRODUCT, DUOC-01, PROMOTES REMYELINATION BY DRIVING THE DIFFERENTIATION OF OPC
L Xu, A Saha, R Parrott, S O'Neil, J Kurtzberg, AJ Filiano
CYTOTHERAPY 24 (5), S26-S26, 2022
2022
Astrocyte immunosenescence in IL-10 and cholesterol signaling in the aged brain impairs microglial regulation following peripheral immune activation
SM O'Neil, EE Hans, S Jiang, LM Wangler, JP Godbout
Brain, Behavior, and Immunity 98, 37, 2021
2021
Correction: Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress.
DJ DiSabato, DP Nemeth, X Liu, KG Witcher, SM O'Neil, B Oliver, CE Bray, ...
Molecular Psychiatry 26 (9), 4783-4783, 2021
2021
How Dysfunctional Microglia/Astrocyte Signaling Leads to Age-Associated Neuroinflammation and Cognitive Impairment
SM O'Neil
The Ohio State University, 2021
2021
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