Sriram Kosuri
Sriram Kosuri
Associate Professor, Dept. of Chemistry & Biochemistry, UCLA
Verified email at - Homepage
Cited by
Cited by
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
P Mali, J Aach, PB Stranges, KM Esvelt, M Moosburner, S Kosuri, L Yang, ...
Nature biotechnology 31 (9), 833-838, 2013
Next-generation digital information storage in DNA
GM Church, Y Gao, S Kosuri
Science 337 (6102), 1628-1628, 2012
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
F Zhang, L Cong, S Lodato, S Kosuri, GM Church, P Arlotta
Nature biotechnology 29 (2), 149-153, 2011
Large-scale de novo DNA synthesis: technologies and applications
S Kosuri, GM Church
Nature methods 11 (5), 499-507, 2014
Causes and effects of N-terminal codon bias in bacterial genes
DB Goodman, GM Church, S Kosuri
Science 342 (6157), 475-479, 2013
Composability of regulatory sequences controlling transcription and translation in Escherichia coli
S Kosuri, DB Goodman, G Cambray, VK Mutalik, Y Gao, AP Arkin, D Endy, ...
Proceedings of the National Academy of Sciences 110 (34), 14024-14029, 2013
Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips
S Kosuri, N Eroshenko, EM LeProust, M Super, J Way, JB Li, GM Church
Nature biotechnology 28 (12), 1295-1299, 2010
Refactoring bacteriophage T7
LY Chan, S Kosuri, D Endy
Molecular systems biology 1 (1), 2005.0018, 2005
Engineering an allosteric transcription factor to respond to new ligands
ND Taylor, AS Garruss, R Moretti, S Chan, MA Arbing, D Cascio, ...
Nature methods 13 (2), 177-183, 2016
Probing the limits of genetic recoding in essential genes
MJ Lajoie, S Kosuri, JA Mosberg, CJ Gregg, D Zhang, GM Church
Science 342 (6156), 361-363, 2013
Assembly of nucleic acid sequences in emulsions
GM Church, RC Terry, S Kosuri, D Zhang
US Patent 10,202,628, 2019
Multiplexed gene synthesis in emulsions for exploring protein functional landscapes
C Plesa, AM Sidore, NB Lubock, D Zhang, S Kosuri
Science 359 (6373), 343-347, 2018
Structural and functional characterization of G protein–coupled receptors with deep mutational scanning
EM Jones, NB Lubock, AJ Venkatakrishnan, J Wang, AM Tseng, JM Paggi, ...
Elife 9, e54895, 2020
A multiplexed assay for exon recognition reveals that an unappreciated fraction of rare genetic variants cause large-effect splicing disruptions
R Cheung, KD Insigne, D Yao, CP Burghard, J Wang, YHE Hsiao, ...
Molecular cell 73 (1), 183-194. e8, 2019
Metagenomic mining of regulatory elements enables programmable species-selective gene expression
NI Johns, ALC Gomes, SS Yim, A Yang, T Blazejewski, CS Smillie, ...
Nature methods 15 (5), 323-329, 2018
Transcription activator-like effectors
F Zhang, L Cong, S Kosuri, GM Church
US Patent 9,499,592, 2016
Engineered CO2 fixing microorganisms producing carbon-based products of interest
DA Berry, DE Robertson, FA Skraly, BD Green, CP Ridley, S Kosuri, ...
US Patent 7,981,647, 2011
Systematic Dissection of Sequence Elements Controlling σ70 Promoters Using a Genomically Encoded Multiplexed Reporter Assay in Escherichia coli
G Urtecho, AD Tripp, KD Insigne, H Kim, S Kosuri
Biochemistry 58 (11), 1539-1551, 2018
Highly parallel genome variant engineering with CRISPR–Cas9
MJ Sadhu, JS Bloom, L Day, JJ Siegel, S Kosuri, L Kruglyak
Nature genetics 50 (4), 510-514, 2018
Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism
N Matoba, D Liang, H Sun, N AygŁn, JC McAfee, JE Davis, LM Raffield, ...
Translational psychiatry 10 (1), 265, 2020
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