Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines Y Li, SC Chan, LJ Brand, TH Hwang, KAT Silverstein, SM Dehm Cancer research 73 (2), 483-489, 2013 | 741 | 2013 |
Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear … SC Chan, Y Li, SM Dehm Journal of Biological Chemistry 287 (23), 19736-19749, 2012 | 268 | 2012 |
Axin is a scaffold protein in TGF‐β signaling that promotes degradation of Smad7 by Arkadia W Liu, H Rui, J Wang, S Lin, Y He, M Chen, Q Li, Z Ye, S Zhang, SC Chan, ... The EMBO journal 25 (8), 1646-1658, 2006 | 207 | 2006 |
Effects of the anti-bacterial peptide cecropin B and its analogs, cecropins B-1 and B-2, on liposomes, bacteria, and cancer cells HM Chen, W Wang, D Smith, SC Chan Biochimica et Biophysica Acta (BBA)-General subjects 1336 (2), 171-179, 1997 | 206 | 1997 |
Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies SC Chan, LA Selth, Y Li, MD Nyquist, L Miao, JE Bradner, GV Raj, ... Nucleic acids research 43 (12), 5880-5897, 2015 | 158 | 2015 |
Enhancement of the cytolytic effect of anti-bacterial cecropin by the microvilli of cancer cells. SC Chan, L Hui, HM Chen Anticancer research 18 (6A), 4467-4474, 1998 | 139 | 1998 |
Constitutive activity of the androgen receptor SC Chan, SM Dehm Advances in pharmacology 70, 327-366, 2014 | 78 | 2014 |
β-actin is required for mitochondria clustering and ROS generation in TNF-induced, caspase-independent cell death J Li, Q Li, C Xie, H Zhou, Y Wang, N Zhang, H Shao, SC Chan, X Peng, ... Journal of cell science 117 (20), 4673-4680, 2004 | 75 | 2004 |
Microscopic observations of the different morphological changes caused by anti‐bacterial peptides on Klebsiella pneumoniae and HL‐60 leukemia cells SC Chan, WL Yau, W Wang, DK Smith, FS Sheu, HM Chen Journal of peptide science: an official publication of the European Peptide …, 1998 | 74 | 1998 |
Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways Y Zhang, WJ Qiu, SC Chan, J Han, X He, SC Lin Journal of Biological Chemistry 277 (20), 17706-17712, 2002 | 63 | 2002 |
Mechanism of fibrosis in HNF1B-related autosomal dominant tubulointerstitial kidney disease SC Chan, Y Zhang, A Shao, S Avdulov, J Herrera, K Aboudehen, ... Journal of the American Society of Nephrology 29 (10), 2493-2509, 2018 | 61 | 2018 |
A β-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by Aida Y Rui, Z Xu, B Xiong, Y Cao, S Lin, M Zhang, SC Chan, W Luo, Y Han, ... Developmental cell 13 (2), 268-282, 2007 | 55 | 2007 |
Transmission electron microscopic observations of membrane effects of antibiotic cecropin B on Escherichia coli HM Chen, SC Chan, JC Lee, CC Chang, M Murugan, RW Jack Microscopy Research and Technique 62 (5), 423-430, 2003 | 50 | 2003 |
Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling K Aboudehen, S Farahani, M Kanchwala, SC Chan, S Avdulov, ... Journal of Biological Chemistry 293 (24), 9388-9398, 2018 | 33 | 2018 |
Regulation of Cidea protein stability by the ubiquitin-mediated proteasomal degradation pathway SC Chan, SC Lin, P Li Biochemical journal 408 (2), 259-266, 2007 | 33 | 2007 |
Role of transcription factor hepatocyte nuclear factor-1β in polycystic kidney disease A Shao, SC Chan, P Igarashi Cellular signalling 71, 109568, 2020 | 29 | 2020 |
Hepatocyte nuclear factor-1β regulates Wnt signaling through genome-wide competition with β-catenin/lymphoid enhancer binding factor SC Chan, Y Zhang, M Pontoglio, P Igarashi Proceedings of the National Academy of Sciences 116 (48), 24133-24142, 2019 | 24 | 2019 |
Significance of local electrostatic interactions in staphylococcal nuclease studied by site-directed mutagenesis KW Leung, YC Liaw, SC Chan, HY Lo, FN Musayev, JZW Chen, HJ Fang, ... Journal of Biological Chemistry 276 (49), 46039-46045, 2001 | 17 | 2001 |
Local stability identification and the role of key acidic amino acid residues in staphylococcal nuclease unfolding HM Chen, SC Chan, KW Leung, JM Wu, HJ Fang, TY Tsong The FEBS journal 272 (15), 3967-3974, 2005 | 12 | 2005 |
Hepatocyte nuclear factor 1β suppresses canonical Wnt signaling through transcriptional repression of lymphoid enhancer–binding factor 1 SC Chan, SS Hajarnis, SM Vrba, V Patel, P Igarashi Journal of Biological Chemistry 295 (51), 17560-17572, 2020 | 4 | 2020 |