Sebastian Hiller

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Gerhard WagnerHarvard Medical SchoolVerified email at hms.harvard.edu
Björn M. BurmannAssociate Professor, Department of Chemistry & Molecular Biology, Wallenberg Centre (WCMTM)Verified email at gu.se
Petr BrozFull Professor, Department of Biochemistry, University of LausanneVerified email at unil.ch
Daniel J MullerETH Zurich, Department of Biosystems Science and EngineeringVerified email at bsse.ethz.ch
Timm MaierBiozentrum, University of BaselVerified email at unibas.ch
Roman P. JakobUniversity of Basel,Verified email at unibas.ch
Henning StahlbergProfessor for Physics, EPFL, SwitzerlandVerified email at epfl.ch
Vladislav Y OrekhovDepartment of Chemistry and Molecular Biology, University of GothenburgVerified email at nmr.gu.se
Sebastian RühlSenior Researcher at T3 Pharmaceuticals AGVerified email at stjude.org
Rosalie HeiligBeatson Institute for Cancer ResearchVerified email at glasgow.ac.uk
Urs JenalBiozentrum - University of BaselVerified email at unibas.ch
Badri N DubeyTenure-Track Scientist,Centre for Structural Systems Biology (CSSB) Deutsches Elektronen-SynchrotronVerified email at desy.de
Tim SharpeUniversity of BaselVerified email at unibas.ch
Peter BondBII A*STARVerified email at bii.a-star.edu.sg
Guillaume MasBiozentrum - University BaselVerified email at unibas.ch
Elia AgustoniUniversity of BaselVerified email at unibas.ch
Marco ColombiniProfessor of Biology, University of MarylandVerified email at umd.edu
Tsyryan YuAssociate Research FellowVerified email at g.iams.sinica.edu.tw
Kim LewisUniversity Distinguished Professor, Northeastern UniversityVerified email at neu.edu
Hundeep KaurPostDocVerified email at unibas.ch

Sebastian Hiller

Professor for Structural Biology and Biophysics, Biozentrum, University Basel, Switzerland

Verified email at unibas.ch

Structural Biology NMR Spectroscopy


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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death L Sborgi, S Rühl, E Mulvihill, J Pipercevic, R Heilig, H Stahlberg, ... The EMBO Journal 35 (16), 1766-1778, 2016	870	2016
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles S Hiller, RG Garces, TJ Malia, VY Orekhov, M Colombini, G Wagner Science 321 (5893), 1206-1210, 2008	730	2008
A new antibiotic selectively kills Gram-negative pathogens Y Imai, KJ Meyer, A Iinishi, Q Favre-Godal, R Green, S Manuse, M Caboni, ... Nature 576 (7787), 459-464, 2019	453	2019
Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ... Cell 167 (1), 187-202. e17, 2016	351	2016
ASC filament formation serves as a signal amplification mechanism for inflammasomes MS Dick, L Sborgi, S Rühl, S Hiller, P Broz Nature communications 7 (1), 11929, 2016	321	2016
The Gasdermin‐D pore acts as a conduit for IL‐1β secretion in mice R Heilig, MS Dick, L Sborgi, E Meunier, S Hiller, P Broz European journal of immunology 48 (4), 584-592, 2018	303	2018
Automated projection spectroscopy (APSY) S Hiller, F Fiorito, K Wüthrich, G Wider Proceedings of the National Academy of Sciences of the United States of …, 2005	272	2005
Chimeric peptidomimetic antibiotics against Gram-negative bacteria A Luther, M Urfer, M Zahn, M Müller, SY Wang, M Mondal, A Vitale, ... Nature 576 (7787), 452-458, 2019	227	2019
Mechanism of membrane pore formation by human gasdermin‐D E Mulvihill, L Sborgi, SA Mari, M Pfreundschuh, S Hiller, DJ Müller The EMBO journal 37 (14), e98321, 2018	211	2018
Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication C Lori, S Ozaki, S Steiner, R Böhm, S Abel, BN Dubey, T Schirmer, ... Nature 523 (7559), 236-239, 2015	195	2015
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains C Suzuki, RG Garces, KA Edmonds, S Hiller, SG Hyberts, A Marintchev, ... Proceedings of the National Academy of Sciences 105 (9), 3274-3279, 2008	194	2008
Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs T Raschle, S Hiller, TY Yu, AJ Rice, T Walz, G Wagner Journal of the American Chemical Society 131 (49), 17777-17779, 2009	193	2009
A Proton‐Detected 4D Solid‐State NMR Experiment for Protein Structure Determination M Huber, S Hiller, P Schanda, M Ernst, A Böckmann, R Verel, BH Meier ChemPhysChem 12 (5), 915-918, 2011	179	2011
Regulation of α-synuclein by chaperones in mammalian cells BM Burmann, JA Gerez, I Matečko-Burmann, S Campioni, P Kumari, ... Nature 577 (7788), 127-132, 2020	166	2020
NMR structure of the apoptosis-and inflammation-related NALP1 pyrin domain S Hiller, A Kohl, F Fiorito, T Herrmann, G Wider, J Tschopp, MG Grütter, ... Structure 11 (10), 1199-1205, 2003	154	2003
HP1(Swi6) Mediates the Recognition and Destruction of Heterochromatic RNA Transcripts C Keller, R Adaixo, R Stunnenberg, KJ Woolcock, S Hiller, M Bühler Molecular Cell, 2012	147	2012
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy L Sborgi, F Ravotti, VP Dandey, MS Dick, A Mazur, S Reckel, M Chami, ... Proceedings of the National Academy of Sciences 112 (43), 13237-13242, 2015	146	2015
The 3D structures of VDAC represent a native conformation S Hiller, J Abramson, C Mannella, G Wagner, K Zeth Trends in biochemical sciences 35 (9), 514-521, 2010	140	2010
Conformation and dynamics of the periplasmic membrane-protein–chaperone complexes OmpX–Skp and tOmpA–Skp BM Burmann, C Wang, S Hiller Nature Structural and Molecular Biology 20 (11), 1265, 2013	138	2013
Nonmicellar systems for solution NMR spectroscopy of membrane proteins T Raschle, S Hiller, M Etzkorn, G Wagner Current opinion in structural biology 20 (4), 471-479, 2010	135	2010

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