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Oleksii Rukhlenko
Oleksii Rukhlenko
Systems Biology Ireland, University College Dublin
Verified email at ucd.ie - Homepage
Title
Cited by
Cited by
Year
MAPK kinase signalling dynamics regulate cell fate decisions and drug resistance
N Rauch, OS Rukhlenko, W Kolch, BN Kholodenko
Current Opinion in Structural Biology 41, 151-158, 2016
952016
The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells
D Fey, D Matallanas, J Rauch, OS Rukhlenko, BN Kholodenko
Seminars in cell & developmental biology 58, 96-107, 2016
762016
Dissecting RAF inhibitor resistance by structure-based modeling reveals ways to overcome oncogenic RAS signaling
OS Rukhlenko, F Khorsand, A Krstic, J Rozanc, LG Alexopoulos, N Rauch, ...
Cell systems 7 (2), 161-179. e14, 2018
572018
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
SA Kennedy, MA Jarboui, S Srihari, C Raso, K Bryan, L Dernayka, ...
Nature communications 11 (1), 499, 2020
492020
Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration
BNK Alfonso Bolado-Carrancio, Oleksii S Rukhlenko, Elena Nikonova, Mikhail A ...
eLife 9, e58165, 2020
432020
Mathematical modeling of intravascular blood coagulation under wall shear stress
OS Rukhlenko, OA Dudchenko, KE Zlobina, GT Guria
PloS one 10 (7), e0134028, 2015
372015
Control of cell state transitions
OS Rukhlenko, M Halasz, N Rauch, V Zhernovkov, T Prince, K Wynne, ...
Nature 609 (7929), 975-985, 2022
332022
Reconstructing static and dynamic models of signaling pathways using Modular Response Analysis
T Santra, O Rukhlenko, V Zhernovkov, BN Kholodenko
Current Opinion in Systems Biology 9, 11-21, 2018
232018
New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling
KE Erickson, OS Rukhlenko, RG Posner, WS Hlavacek, BN Kholodenko
Seminars in cancer biology 54, 162-173, 2019
192019
A systematic analysis of signaling reactivation and drug resistance
BN Kholodenko, N Rauch, W Kolch, OS Rukhlenko
Cell reports 35 (8), 2021
172021
Region-specific changes in activities of cell death-related proteases and nitric oxide metabolism in rat brain in a chronic unpredictable stress model
A Tishkina, A Rukhlenko, M Stepanichev, I Levshina, N Pasikova, ...
Metabolic brain disease 27, 431-441, 2012
162012
Impact of measurement noise, experimental design, and estimation methods on Modular Response Analysis based network reconstruction
C Thomaseth, D Fey, T Santra, OS Rukhlenko, NE Radde, ...
Scientific reports 8 (1), 16217, 2018
142018
Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
S Chatterjee, SM Yabaji, OS Rukhlenko, B Bhattacharya, E Waligurski, ...
Iscience 24 (8), 2021
122021
An integrative computational approach for a prioritization of key transcription regulators associated with nanomaterial-induced toxicity
V Zhernovkov, T Santra, H Cassidy, O Rukhlenko, D Matallanas, A Krstic, ...
Toxicological Sciences 171 (2), 303-314, 2019
122019
Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor
KE Erickson, OS Rukhlenko, M Shahinuzzaman, KP Slavkova, YT Lin, ...
PLoS computational biology 15 (1), e1006706, 2019
122019
Гидродинамическая активация свертывания крови в стенозированных сосудах. Теоретический анализ
АС Рухленко, КЕ Злобина, ГТ Гурия
Компьютерные исследования и моделирование 4 (1), 155-183, 2012
122012
Mapping connections in signaling networks with ambiguous modularity
D Lill, OS Rukhlenko, AJ Mc Elwee, E Kashdan, J Timmer, ...
NPJ Systems Biology and Applications 5 (1), 19, 2019
82019
Hydrodynamical activation of blood coagulation in stenosed vessels. Theoretical analysis
AS Rukhlenko, KE Zlobina, GT Guria
Computer research and modeling 4 (1), 155-183, 2012
62012
Dissecting RAF Inhibitor Resistance by Structure-based Modeling Reveals Ways to Overcome Oncogenic RAS Signaling. Cell Syst. 2018 Aug; 7 (2): 161–179. e14
OS Rukhlenko, F Khorsand, A Krstic, J Rozanc, LG Alexopoulos, N Rauch
6
Reversing pathological cell states: The road less travelled can extend the therapeutic horizon
BN Kholodenko, W Kolch, OS Rukhlenko
Trends in Cell Biology 33 (11), 913-923, 2023
52023
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