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Nazem Atassi
Nazem Atassi
Associate Professor of Neurology, Harvard Medical School
Adresse e-mail validée de mgh.harvard.edu
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Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ...
New England Journal of Medicine 383 (2), 109-119, 2020
4322020
The PRO-ACT database: design, initial analyses, and predictive features
N Atassi, J Berry, A Shui, N Zach, A Sherman, E Sinani, J Walker, ...
Neurology 83 (19), 1719-1725, 2014
2642014
Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: assessed with [11C]-PBR28
NR Zürcher, ML Loggia, R Lawson, DB Chonde, D Izquierdo-Garcia, ...
NeuroImage: Clinical 7, 409-414, 2015
2182015
Diagnostic timelines and delays in diagnosing amyotrophic lateral sclerosis (ALS)
S Paganoni, EA Macklin, A Lee, A Murphy, J Chang, A Zipf, M Cudkowicz, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 15 (5-6), 453-456, 2014
2182014
Postmortem cortex samples identify distinct molecular subtypes of ALS: retrotransposon activation, oxidative stress, and activated glia
OH Tam, NV Rozhkov, R Shaw, D Kim, I Hubbard, S Fennessey, N Propp, ...
Cell reports 29 (5), 1164-1177. e5, 2019
2162019
Transplantation of spinal cord–derived neural stem cells for ALS: analysis of phase 1 and 2 trials
JD Glass, VS Hertzberg, NM Boulis, J Riley, T Federici, M Polak, ...
Neurology 87 (4), 392-400, 2016
1502016
Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressive SOD1 ALS
M Benatar, J Wuu, PM Andersen, N Atassi, W David, M Cudkowicz, ...
Neurology 90 (7), e565-e574, 2018
1292018
ALS biomarkers for therapy development: state of the field and future directions
M Benatar, K Boylan, A Jeromin, SB Rutkove, J Berry, N Atassi, L Bruijn
Muscle & nerve 53 (2), 169-182, 2016
1212016
Depression in amyotrophic lateral sclerosis
N Atassi, A Cook, CME Pineda, P Yerramilli-Rao, D Pulley, M Cudkowicz
Amyotrophic Lateral Sclerosis 12 (2), 109-112, 2011
1152011
Randomized phase 2 trial of NP001, a novel immune regulator: Safety and early efficacy in ALS
RG Miller, G Block, JS Katz, RJ Barohn, V Gopalakrishnan, M Cudkowicz, ...
Neuroimmunology & Neuroinflammation 2 (3), e100, 2015
1002015
Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis
MJ Alshikho, NR Zürcher, ML Loggia, P Cernasov, DB Chonde, ...
Neurology 87 (24), 2554-2561, 2016
982016
A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression
MD Weiss, EA Macklin, Z Simmons, AS Knox, DJ Greenblatt, N Atassi, ...
Neurology 86 (16), 1474-1481, 2016
972016
Integrated magnetic resonance imaging and [11C]‐PBR28 positron emission tomographic imaging in amyotrophic lateral sclerosis
MJ Alshikho, NR Zürcher, ML Loggia, P Cernasov, B Reynolds, ...
Annals of neurology 83 (6), 1186-1197, 2018
962018
Effect of ezogabine on cortical and spinal motor neuron excitability in amyotrophic lateral sclerosis: a randomized clinical trial
BJ Wainger, EA Macklin, S Vucic, CE McIlduff, S Paganoni, NJ Maragakis, ...
JAMA neurology 78 (2), 186-196, 2021
952021
Defining SOD1 ALS natural history to guide therapeutic clinical trial design
T Bali, W Self, J Liu, T Siddique, LH Wang, TD Bird, E Ratti, N Atassi, ...
Journal of Neurology, Neurosurgery & Psychiatry 88 (2), 99-105, 2017
812017
A randomized controlled trial of resistance and endurance exercise in amyotrophic lateral sclerosis
LL Clawson, M Cudkowicz, L Krivickas, BR Brooks, M Sanjak, P Allred, ...
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19 (3-4), 250-258, 2018
692018
Pathogenic huntingtin repeat expansions in patients with frontotemporal dementia and amyotrophic lateral sclerosis
R Dewan, R Chia, J Ding, RA Hickman, TD Stein, Y Abramzon, S Ahmed, ...
Neuron 109 (3), 448-460. e4, 2021
662021
Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach
R Kueffner, N Zach, M Bronfeld, R Norel, N Atassi, V Balagurusamy, ...
Scientific reports 9 (1), 690, 2019
662019
Analysis of start-up, retention, and adherence in ALS clinical trials
N Atassi, P Yerramilli-Rao, J Szymonifka, H Yu, M Kearney, D Grasso, ...
Neurology 81 (15), 1350-1355, 2013
582013
Head-to-head comparison of 11C-PBR28 and 18F-GE180 for quantification of the translocator protein in the human brain
P Zanotti-Fregonara, B Pascual, G Rizzo, M Yu, N Pal, D Beers, R Carter, ...
Journal of Nuclear Medicine 59 (8), 1260-1266, 2018
572018
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