Peter Keightley
Peter Keightley
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Evolution of genes and genomes on the Drosophila phylogeny
AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ...
Nature 450 (7167), 203-18, 2007
The distribution of fitness effects of new mutations
A Eyre-Walker, PD Keightley
Nature Reviews Genetics 8 (8), 610-618, 2007
Understanding quantitative genetic variation
NH Barton, PD Keightley
Nature Reviews Genetics 3 (1), 11-21, 2002
High genomic deleterious mutation rates in hominids
A Eyre-Walker, PD Keightley
Nature 397 (6717), 344-347, 1999
Spontaneous mutation accumulation studies in evolutionary genetics
DL Halligan, PD Keightley
Annual Review of Ecology, Evolution, and Systematics 40 (1), 151-172, 2009
Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change
A Eyre-Walker, PD Keightley
Molecular biology and evolution 26 (9), 2097-2108, 2009
Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila
C Haag-Liautard, M Dorris, X Maside, S Macaskill, DL Halligan, ...
Nature 445 (7123), 82-85, 2007
Interference among deleterious mutations favours sex and recombination in finite populations
PD Keightley, SP Otto
Nature 443 (7107), 89-92, 2006
Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice
CB Millar, J Guy, OJ Sansom, J Selfridge, E MacDougall, B Hendrich, ...
Science 297 (5580), 403-405, 2002
Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines
PD Keightley, U Trivedi, M Thomson, F Oliver, S Kumar, ML Blaxter
Genome research 19 (7), 1195-1201, 2009
Joint inference of the distribution of fitness effects of deleterious mutations and population demography based on nucleotide polymorphism frequencies
PD Keightley, A Eyre-Walker
Genetics 177 (4), 2251-2261, 2007
Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster
C Haag-Liautard, N Coffey, D Houle, M Lynch, B Charlesworth, ...
PLoS biology 6 (8), e204, 2008
Genomic mutation rates for lifetime reproductive output and lifespan in Caenorhabditis elegans
PD Keightley, A Caballero
Proceedings of the National Academy of Sciences 94 (8), 3823-3827, 1997
Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison
DL Halligan, PD Keightley
Genome research 16 (7), 875-884, 2006
Estimation of the Spontaneous Mutation Rate per Nucleotide Site in a Drosophila melanogaster Full-Sib Family
PD Keightley, RW Ness, DL Halligan, PR Haddrill
Genetics 196 (1), 313-320, 2014
The distribution of mutation effects on viability in Drosophila melanogaster.
PD Keightley
Genetics 138 (4), 1315-1322, 1994
Deleterious mutations and the evolution of sex
PD Keightley, A Eyre-Walker
Science 290 (5490), 331-333, 2000
Estimation of the Spontaneous Mutation Rate in Heliconius melpomene
PD Keightley, A Pinharanda, RW Ness, F Simpson, KK Dasmahapatra, ...
Molecular biology and evolution 32 (1), 239-243, 2015
Evidence for widespread degradation of gene control regions in hominid genomes
PD Keightley, MJ Lercher, A Eyre-Walker
PLoS biology 3 (2), e42, 2005
Quantifying the slightly deleterious mutation model of molecular evolution
A Eyre-Walker, PD Keightley, NGC Smith, D Gaffney
Molecular Biology and Evolution 19 (12), 2142-2149, 2002
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