Andrei Gudkov
Andrei Gudkov
Professor of Roswell Park Comprehensive Cancer Center
Verified email at
Cited by
Cited by
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
PG Komarov, EA Komarova, RV Kondratov, K Christov-Tselkov, JS Coon, ...
Science 285 (5434), 1733-1737, 1999
An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models
LG Burdelya, VI Krivokrysenko, TC Tallant, E Strom, AS Gleiberman, ...
Science 320 (5873), 226-230, 2008
The role of p53 in determining sensitivity to radiotherapy
AV Gudkov, EA Komarova
Nature Reviews Cancer 3 (2), 117-129, 2003
Structural basis of TLR5-flagellin recognition and signaling
S Yoon, O Kurnasov, V Natarajan, M Hong, AV Gudkov, AL Osterman, ...
Science 335 (6070), 859-864, 2012
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
I Garkavtsev, A Kazarov, A Gudkov, K Riabowol
Nature genetics 14 (4), 415-420, 1996
The candidate tumour suppressor p33ING1cooperates with p53 in cell growth control
I Garkavtsev, IA Grigorian, VS Ossovskaya, MV Chernov, PM Chumakov, ...
Nature 391 (6664), 295-298, 1998
Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53
SS Bacus, AV Gudkov, M Lowe, L Lyass, Y Yung, AP Komarov, ...
Oncogene 20 (2), 147-155, 2001
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability
AV Budanov, T Shoshani, A Faerman, E Zelin, I Kamer, H Kalinski, ...
Oncogene 21 (39), 6017-6031, 2002
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
E Strom, S Sathe, PG Komarov, OB Chernova, I Pavlovska, I Shyshynova, ...
Nature chemical biology 2 (9), 474-479, 2006
Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo
EA Komarova, MV Chernov, R Franks, K Wang, G Armin, CR Zelnick, ...
The EMBO journal 16 (6), 1391-1400, 1997
LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation
M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ...
Cell metabolism 29 (4), 871-885. e5, 2019
Aging of mice is associated with p16 (Ink4a)-and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
BM Hall, V Balan, AS Gleiberman, E Strom, P Krasnov, LP Virtuoso, ...
Aging (Albany NY) 8 (7), 1294, 2016
Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65
T Lu, MW Jackson, B Wang, M Yang, MR Chance, M Miyagi, AV Gudkov, ...
Proceedings of the National Academy of Sciences 107 (1), 46-51, 2010
Core circadian protein CLOCK is a positive regulator of NF-κB–mediated transcription
ML Spengler, KK Kuropatwinski, M Comas, AV Gasparian, N Fedtsova, ...
Proceedings of the National Academy of Sciences 109 (37), E2457-E2465, 2012
The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway
LG Korotchkina, OV Leontieva, EI Bukreeva, ZN Demidenko, AV Gudkov, ...
Aging (Albany NY) 2 (6), 344, 2010
Paradoxical suppression of cellular senescence by p53
ZN Demidenko, LG Korotchkina, AV Gudkov, MV Blagosklonny
Proceedings of the National Academy of Sciences 107 (21), 9660-9664, 2010
Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex
VY Gorbacheva, RV Kondratov, R Zhang, S Cherukuri, AV Gudkov, ...
Proceedings of the National Academy of Sciences 102 (9), 3407-3412, 2005
p16 (Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli
BM Hall, V Balan, AS Gleiberman, E Strom, P Krasnov, LP Virtuoso, ...
Aging (Albany NY) 9 (8), 1867, 2017
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
RV Kondratov, MV Chernov, AA Kondratova, VY Gorbacheva, AV Gudkov, ...
Genes & development 17 (15), 1921-1932, 2003
Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-κB-dependent mechanism of p53 suppression in tumors
KV Gurova, JE Hill, C Guo, A Prokvolit, LG Burdelya, E Samoylova, ...
Proceedings of the National Academy of Sciences 102 (48), 17448-17453, 2005
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