Flex ddG: Rosetta ensemble-based estimation of changes in protein–protein binding affinity upon mutation KA Barlow, S Ó Conchúir, S Thompson, P Suresh, JE Lucas, M Heinonen, ... The Journal of Physical Chemistry B 122 (21), 5389-5399, 2018 | 191 | 2018 |
qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps GCP van Zundert, BM Hudson, SHP de Oliveira, DA Keedy, R Fonseca, ... Journal of medicinal chemistry 61 (24), 11183-11198, 2018 | 48 | 2018 |
Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes P Suresh, AF Long, S Dumont Elife 9, e53807, 2020 | 36 | 2020 |
The spindle: Integrating architecture and mechanics across scales MW Elting, P Suresh, S Dumont Trends in cell biology 28 (11), 896-910, 2018 | 35 | 2018 |
Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure AF Long, P Suresh, S Dumont Journal of Cell Biology 219 (8), 2020 | 22 | 2020 |
Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance D Mavor, KA Barlow, D Asarnow, Y Birman, D Britain, W Chen, EM Green, ... Biology Open 7 (7), bio036103, 2018 | 21 | 2018 |
Structure‐based simulations reveal concerted dynamics of GPCR activation N Leioatts, P Suresh, TD Romo, A Grossfield Proteins: Structure, Function, and Bioinformatics 82 (10), 2538-2551, 2014 | 9 | 2014 |
The Astrin/SKAP Complex Reduces Friction at the Kinetochore-Microtubule Interface R Sutanto, P Suresh, S Dumont | 8* | 2021 |
The Astrin-SKAP Complex Reduces Friction at the Kinetochore-Microtubule Interface M Rosas-Salvans, R Sutanto, P Suresh, S Dumont bioRxiv, 2021 | 8 | 2021 |
A semiconductor 96-microplate platform for electrical-imaging based high-throughput phenotypic screening S Chitale, W Wu, A Mukherjee, H Lannon, P Suresh, I Nag, CM Ambrosi, ... Nature Communications 14 (1), 7576, 2023 | 1 | 2023 |
Modeling and mechanical perturbations reveal how spatially regulated anchorage gives rise to spatially distinct mechanics across the mammalian spindle P Suresh, V Galstyan, R Phillips, S Dumont arXiv preprint arXiv:2204.04461, 2022 | 1 | 2022 |
Connections distributed within 3 μm of chromosomes are necessary and sufficient for the kinetochore-fiber’s robust anchorage in the mammalian spindle P Suresh, V Galstyan, R Phillips, S Dumont Biophysical Journal 121 (3), 448a-449a, 2022 | | 2022 |
Understanding the Mechanisms that Give Rise to the Mammalian Spindle's Response to Force using Theory and Microneedle Manipulation V Galstyan, P Suresh, S Dumont, R Phillips Biophysical Journal 120 (3), 347a, 2021 | | 2021 |
Microneedle manipulation of the mammalian spindle suggests specialized microtubule crosslinking near chromosomes. P Suresh, AF Long, S Dumont MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
Probing the mechanisms underlying the mechanical robustness of the mammalian kinetochore-microtubule interface using microneedle manipulation. AF Long, P Suresh, S Dumont MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
Here are some recent publications by our faculty, postdocs, and graduate students. These publications reflect the broad interests of our department and collaborative … MW Elting, P Suresh, S Dumont Genetics 50 (8), 1132-1139, 2018 | | 2018 |
Probing How the Mammalian Kinetochore Holds on to Growing versus Shrinking Microtubules AF Long, DB Udy, P Suresh, S Dumont Biophysical Journal 114 (3), 518a, 2018 | | 2018 |
Probing the Physical and Molecular Basis of the Mammalian Mitotic Spindle's Response to Force P Suresh, AF Long, S Dumont Biophysical Journal 114 (3), 655a, 2018 | | 2018 |
Objectively and automatically building multi-conformer ligand models in electron densities G Van Zundert, D Keedy, P Suresh, A Héliou, K Borrelli, T Day, J Fraser, ... Conformational ensembles from experimental data and computer simulations, 2017 | | 2017 |
Research Advance: Extending chemical perturbations of the Ubiquitin fitness landscape in a classroom setting D Mavor, KA Barlow, D Asarnow, Y Birman, D Britain, W Chen, EM Green, ... bioRxiv, 139352, 2017 | | 2017 |