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F J Raal
F J Raal
Verified email at wits.ac.za
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Heart disease and stroke statistics—2017 update: a report from the American Heart Association
EJ Benjamin, MJ Blaha, SE Chiuve, M Cushman, SR Das, R Deo, ...
circulation 135 (10), e146-e603, 2017
250062017
Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European …
BA Ference, HN Ginsberg, I Graham, KK Ray, CJ Packard, E Bruckert, ...
European heart journal 38 (32), 2459-2472, 2017
32352017
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of …
BG Nordestgaard, MJ Chapman, SE Humphries, HN Ginsberg, L Masana, ...
European heart journal 34 (45), 3478-3490, 2013
30182013
Efficacy and safety of alirocumab in reducing lipids and cardiovascular events
JG Robinson, M Farnier, M Krempf, J Bergeron, G Luc, M Averna, ...
New England Journal of Medicine 372 (16), 1489-1499, 2015
24012015
Efficacy and safety of evolocumab in reducing lipids and cardiovascular events
MS Sabatine, RP Giugliano, SD Wiviott, FJ Raal, DJ Blom, J Robinson, ...
New England Journal of Medicine 372 (16), 1500-1509, 2015
16692015
Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society consensus panel statement on assessment, aetiology and management
ES Stroes, PD Thompson, A Corsini, GD Vladutiu, FJ Raal, KK Ray, ...
European heart journal 36 (17), 1012-1022, 2015
14982015
Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on …
M Cuchel, E Bruckert, HN Ginsberg, FJ Raal, RD Santos, RA Hegele, ...
European heart journal 35 (32), 2146-2157, 2014
11072014
Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European …
J Boren, MJ Chapman, RM Krauss, CJ Packard, JF Bentzon, CJ Binder, ...
European heart journal 41 (24), 2313-2330, 2020
10582020
Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised …
FJ Raal, RD Santos, DJ Blom, AD Marais, MJ Charng, WC Cromwell, ...
The Lancet 375 (9719), 998-1006, 2010
10352010
Two phase 3 trials of inclisiran in patients with elevated LDL cholesterol
KK Ray, RS Wright, D Kallend, W Koenig, LA Leiter, FJ Raal, JA Bisch, ...
New England journal of medicine 382 (16), 1507-1519, 2020
10062020
Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment
A Wiegman, SS Gidding, GF Watts, MJ Chapman, HN Ginsberg, M Cuchel, ...
European heart journal 36 (36), 2425-2437, 2015
9072015
PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial
FJ Raal, EA Stein, R Dufour, T Turner, F Civeira, L Burgess, G Langslet, ...
The Lancet 385 (9965), 331-340, 2015
8702015
Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial
FJ Raal, N Honarpour, DJ Blom, GK Hovingh, F Xu, R Scott, ...
The Lancet 385 (9965), 341-350, 2015
8362015
Low-density lipoprotein cholesterol–lowering effects of AMG 145, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease in patients with …
F Raal, R Scott, R Somaratne, I Bridges, G Li, SM Wasserman, EA Stein
Circulation 126 (20), 2408-2417, 2012
6702012
The agenda for familial hypercholesterolemia: a scientific statement from the American Heart Association
SS Gidding, M Ann Champagne, SD de Ferranti, J Defesche, MK Ito, ...
Circulation 132 (22), 2167-2192, 2015
6582015
Inclisiran for the treatment of heterozygous familial hypercholesterolemia
FJ Raal, D Kallend, KK Ray, T Turner, W Koenig, RS Wright, ...
New England Journal of Medicine 382 (16), 1520-1530, 2020
6292020
The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management
RA Hegele, HN Ginsberg, MJ Chapman, BG Nordestgaard, ...
The lancet Diabetes & endocrinology 2 (8), 655-666, 2014
6102014
Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation
GF Watts, S Gidding, AS Wierzbicki, PP Toth, R Alonso, WV Brown, ...
International journal of cardiology 171 (3), 309-325, 2014
5822014
Evinacumab for homozygous familial hypercholesterolemia
FJ Raal, RS Rosenson, LF Reeskamp, GK Hovingh, JJP Kastelein, ...
New England Journal of Medicine 383 (8), 711-720, 2020
5132020
Open-Label Study of Long-Term Evaluation against LDL Cholesterol (OSLER) Investigators. Efficacy and safety of evolocumab in reducing lipids and cardiovascular events
MS Sabatine, RP Giugliano, SD Wiviott, FJ Raal, DJ Blom, J Robinson, ...
N Engl J Med 372 (16), 1500-1509, 2015
4662015
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