Hitoshi Takizawa
Hitoshi Takizawa
International Research Center for Medical Sciences, Kumamoto University
Verified email at - Homepage
Cited by
Cited by
Demand-adapted regulation of early hematopoiesis in infection and inflammation
H Takizawa, S Boettcher, MG Manz
Blood, The Journal of the American Society of Hematology 119 (13), 2991-3002, 2012
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups
ML Berres, KPH Lim, T Peters, J Price, H Takizawa, H Salmon, J Idoyaga, ...
Journal of Experimental Medicine 211 (4), 669-683, 2014
Human hemato-lymphoid system mice: current use and future potential for medicine
A Rongvaux, H Takizawa, T Strowig, T Willinger, EE Eynon, RA Flavell, ...
Annual review of immunology 31 (1), 635-674, 2013
Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment
LV Kovtonyuk, K Fritsch, X Feng, MG Manz, H Takizawa
Frontiers in immunology 7, 502, 2016
Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation
H Takizawa, RR Regoes, CS Boddupalli, S Bonhoeffer, MG Manz
Journal of Experimental Medicine 208 (2), 273-284, 2011
Engineering of a functional bone organ through endochondral ossification
C Scotti, E Piccinini, H Takizawa, A Todorov, P Bourgine, ...
Proceedings of the National Academy of Sciences 110 (10), 3997-4002, 2013
Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung
T Willinger, A Rongvaux, H Takizawa, GD Yancopoulos, DM Valenzuela, ...
Proceedings of the National Academy of Sciences 108 (6), 2390-2395, 2011
Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo
A Rongvaux, T Willinger, H Takizawa, C Rathinam, W Auerbach, ...
Proceedings of the National Academy of Sciences 108 (6), 2378-2383, 2011
Transgenic expression of human signal regulatory protein alpha in Rag2−/− γc−/− mice improves engraftment of human hematopoietic cells in humanized mice
T Strowig, A Rongvaux, C Rathinam, H Takizawa, C Borsotti, W Philbrick, ...
Proceedings of the National Academy of Sciences 108 (32), 13218-13223, 2011
Humanized mice for modeling human infectious disease: challenges, progress, and outlook
N Legrand, A Ploss, R Balling, PD Becker, C Borsotti, N Brezillon, ...
Cell host & microbe 6 (1), 5-9, 2009
Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness
H Takizawa, K Fritsch, LV Kovtonyuk, Y Saito, C Yakkala, K Jacobs, ...
Cell stem cell 21 (2), 225-240. e5, 2017
The analysis, roles and regulation of quiescence in hematopoietic stem cells
A Nakamura-Ishizu, H Takizawa, T Suda
Development 141 (24), 4656-4666, 2014
Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells
S Boettcher, P Ziegler, MA Schmid, H Takizawa, N van Rooijen, M Kopf, ...
The Journal of Immunology 188 (12), 5824-5828, 2012
Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F
P Lundberg, H Takizawa, L Kubovcakova, G Guo, H Hao-Shen, ...
Journal of Experimental Medicine 211 (11), 2213-2230, 2014
Bone marrow dendritic cell progenitors sense pathogens via Toll-like receptors and subsequently migrate to inflamed lymph nodes
MA Schmid, H Takizawa, DR Baumjohann, Y Saito, MG Manz
Blood, The Journal of the American Society of Hematology 118 (18), 4829-4840, 2011
Lnk regulates integrin αIIbβ3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo
H Takizawa, S Nishimura, N Takayama, A Oda, H Nishikii, Y Morita, ...
The Journal of clinical investigation 120 (1), 179-190, 2010
Macrophage tolerance: CD47–SIRP-α–mediated signals matter
H Takizawa, MG Manz
Nature immunology 8 (12), 1287-1289, 2007
Thrombopoietin metabolically primes hematopoietic stem cells to megakaryocyte-lineage differentiation
A Nakamura-Ishizu, T Matsumura, PS Stumpf, T Umemoto, H Takizawa, ...
Cell Reports 25 (7), 1772-1785. e6, 2018
IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice
LV Kovtonyuk, F Caiado, S Garcia-Martin, EM Manz, P Helbling, ...
Blood, The Journal of the American Society of Hematology 139 (1), 44-58, 2022
iPSC-derived platelets depleted of HLA class I are inert to anti-HLA class I and natural killer cell immunity
D Suzuki, C Flahou, N Yoshikawa, I Stirblyte, Y Hayashi, A Sawaguchi, ...
Stem cell reports 14 (1), 49-59, 2020
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