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Paolo Luraghi
Paolo Luraghi
clinical project manager, IFOM - the FIRC Institute of Molecular Oncology
Adresse e-mail validée de ifom.eu
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Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
F De Bacco, P Luraghi, E Medico, G Reato, F Girolami, T Perera, ...
JNCI: Journal of the National Cancer Institute 103 (8), 645-661, 2011
3732011
The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype
F De Bacco, E Casanova, E Medico, S Pellegatta, F Orzan, R Albano, ...
Cancer research 72 (17), 4537-4550, 2012
1622012
MET signaling in colon cancer stem-like cells blunts the therapeutic response to EGFR inhibitors
P Luraghi, G Reato, E Cipriano, F Sassi, F Orzan, V Bigatto, F De Bacco, ...
Cancer research 74 (6), 1857-1869, 2014
1482014
Poised transcription factories prime silent uPA gene prior to activation
C Ferrai, SQ Xie, P Luraghi, D Munari, F Ramirez, MR Branco, A Pombo, ...
PLoS biology 8 (1), e1000270, 2010
1062010
MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells
F De Bacco, A D'Ambrosio, E Casanova, F Orzan, R Neggia, R Albano, ...
EMBO molecular medicine 8 (5), 550-568, 2016
912016
Temozolomide treatment alters mismatch repair and boosts mutational burden in tumor and blood of colorectal cancer patients
G Crisafulli, A Sartore-Bianchi, L Lazzari, F Pietrantonio, A Amatu, ...
Cancer Discovery 12 (7), 1656-1675, 2022
572022
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype
B Lupo, F Sassi, M Pinnelli, F Galimi, ER Zanella, V Vurchio, G Migliardi, ...
Science translational medicine 12 (555), eaax8313, 2020
402020
MET-mediated resistance to EGFR inhibitors: an old liaison rooted in colorectal cancer stem cells
C Boccaccio, P Luraghi, PM Comoglio
Cancer research 74 (14), 3647-3651, 2014
382014
A molecularly annotated model of patient-derived colon cancer stem–like cells to assess genetic and nongenetic mechanisms of resistance to anti-EGFR therapy
P Luraghi, V Bigatto, E Cipriano, G Reato, F Orzan, F Sassi, F De Bacco, ...
Clinical Cancer Research 24 (4), 807-820, 2018
302018
Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity
V Leuci, F Maione, R Rotolo, E Giraudo, F Sassi, G Migliardi, M Todorovic, ...
Journal of Translational Medicine 14, 1-12, 2016
272016
The PEGASUS trial: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients.
S Lonardi, C Montagut, F Pietrantonio, E Elez, A Sartore-Bianchi, ...
Journal of Clinical Oncology 38 (15_suppl), TPS4124-TPS4124, 2020
222020
The MET oncogene as a therapeutical target in cancer invasive growth
P Luraghi, F Schelter, A Krüger, C Boccaccio
Frontiers in pharmacology 3, 164, 2012
212012
A transcription-dependent micrococcal nuclease-resistant fragment of the urokinase-type plasminogen activator promoter interacts with the enhancer
C Ferrai, D Munari, P Luraghi, L Pecciarini, MG Cangi, C Doglioni, F Blasi, ...
Journal of biological chemistry 282 (17), 12537-12546, 2007
182007
Kinetic assay for characterization of spleen tyrosine kinase activity and inhibition with recombinant kinase and crude cell lysates
M Li, P Luraghi, A Amour, XD Qian, PS Carter, CJ Clark, A Deakin, ...
Analytical biochemistry 384 (1), 56-67, 2009
142009
Pembrolizumab in MMR-proficient metastatic colorectal cancer pharmacologically primed to trigger dynamic hypermutation status: The ARETHUSA trial.
S Siena, A Sartore-Bianchi, N Personeni, F Pietrantonio, G Germano, ...
Journal of Clinical Oncology 37 (15_suppl), TPS2659-TPS2659, 2019
122019
LBA28 The PEGASUS trial: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients
S Lonardi, F Pietrantonio, NT Llavero, CM Viladot, AS Bianchi, ...
Annals of Oncology 34, S1268-S1269, 2023
42023
A transcription-dependent MNase-resistant fragment of the uPA promoter interacts with the enhancer
C Ferrai, D Munari, P Luraghi, L Pecciarini, M Cangi, C Doglioni, F Blasi, ...
J Biol Chem 282, 12537-12546, 2007
42007
MicroRNA 483‐3p overexpression unleashes invasive growth of metastatic colorectal cancer via NDRG1 downregulation and ensuing activation of the ERBB3/AKT …
E Candiello, G Reato, F Verginelli, G Gambardella, A D′ Ambrosio, ...
Molecular Oncology 17 (7), 1280-1301, 2023
12023
miRNA-483-3p overexpression unleashes invasiveness of metastatic colorectal cancer by NDRG1 targeting and upregulation of the HER3-AKT axis
E Candiello, G Reato, F Verginelli, A D'Ambrosio, G Gambardella, ...
Cancer Research 81 (13_Supplement), 2358-2358, 2021
12021
The PEGASUS trial: Post-surgical liquid biopsy-guided treatment of stage III and high-risk stage II colon cancer patients
S Lonardi, F Pietrantonio, NT Llavero, CM Viladot, AS Bianchi, ...
ANNALS OF ONCOLOGY 34, S1268-S1269, 2023
2023
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