A map of open chromatin in human pancreatic islets KJ Gaulton, T Nammo, L Pasquali, JM Simon, PG Giresi, MP Fogarty, ... Nature genetics 42 (3), 255-259, 2010 | 642 | 2010 |
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ... Nature genetics 46 (2), 136-143, 2014 | 559 | 2014 |
Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure DL Eizirik, L Pasquali, M Cnop Nature Reviews Endocrinology 16 (7), 349-362, 2020 | 557 | 2020 |
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes I Morán, I Akerman, M Van De Bunt, R Xie, M Benazra, T Nammo, L Arnes, ... Cell metabolism 16 (4), 435-448, 2012 | 481 | 2012 |
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ... Nature genetics 47 (12), 1415-1425, 2015 | 407 | 2015 |
TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors I Cebola, SA Rodríguez-Seguí, CHH Cho, J Bessa, M Rovira, M Luengo, ... Nature cell biology 17 (5), 615-626, 2015 | 232 | 2015 |
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes I Miguel-Escalada, S Bonàs-Guarch, I Cebola, J Ponsa-Cobas, ... Nature genetics 51 (7), 1137-1148, 2019 | 228 | 2019 |
Human pancreatic β cell lncRNAs control cell-specific regulatory networks I Akerman, Z Tu, A Beucher, DMY Rolando, C Sauty-Colace, M Benazra, ... Cell metabolism 25 (2), 400-411, 2017 | 218 | 2017 |
The impact of proinflammatory cytokines on the β-cell regulatory landscape provides new insights into the genetics of type 1 diabetes M Romas-Rodriquez, H Raurell-Vila, ML Colli, MI Alvelos, M Subirana, ... Nature Genetics 51, 1588–1595, 2019 | 119 | 2019 |
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells ML Colli, M Ramos-Rodríguez, ES Nakayasu, MI Alvelos, M Lopes, ... Nature communications 11 (1), 2584, 2020 | 91 | 2020 |
Wolfram syndrome: new mutations, different phenotype C Aloi, A Salina, L Pasquali, F Lugani, K Perri, C Russo, R Tallone, ... PLoS One 7 (1), e29150, 2012 | 70 | 2012 |
Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinoma L Pasquali, A Bedeir, S Ringquist, A Styche, R Bhargava, G Trucco Cancer letters 257 (1), 136-144, 2007 | 62 | 2007 |
Wolfram syndrome (diabetes insipidus, diabetes, optic atrophy, and deafness) clinical and genetic study G d'Annunzio, N Minuto, E D'Amato, T De Toni, F Lombardo, L Pasquali, ... Diabetes care 31 (9), 1743-1745, 2008 | 61 | 2008 |
Transcriptional enhancers: functional insights and role in human disease I Miguel-Escalada, L Pasquali, J Ferrer Current Opinion in Genetics & Development 33, 71-76, 2015 | 47 | 2015 |
The dysregulation of the DLK1-MEG3 locus in islets from patients with type 2 diabetes is mimicked by targeted epimutation of its promoter with TALE-DNMT constructs V Kameswaran, ML Golson, M Ramos-Rodríguez, K Ou, YJ Wang, ... Diabetes 67 (9), 1807-1815, 2018 | 42 | 2018 |
Association of alleles at polymorphic sites in the osteopontin encoding gene in young type 1 diabetic patients R Marciano, G D'Annunzio, N Minuto, L Pasquali, A Santamaria, ... Clinical immunology 131 (1), 84-91, 2009 | 41 | 2009 |
Induction of immune tolerance to facilitate β cell regeneration in type 1 diabetes L Pasquali, N Giannoukakis, M Trucco Advanced drug delivery reviews 60 (2), 106-113, 2008 | 32 | 2008 |
The pancreatic islet regulome browser L Mularoni, M Ramos-Rodríguez, L Pasquali Frontiers in Genetics 8, 239707, 2017 | 31 | 2017 |
Cis and trans regulatory elements in NPHS2 promoter: Implications in proteinuria and progression of renal diseases M Di Duca, R Oleggini, S Sanna-Cherchi, L Pasquali, A Di Donato, ... Kidney international 70 (7), 1332-1341, 2006 | 28 | 2006 |
Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms M Horikoshi, L Pasquali, S Wiltshire, JR Huyghe, A Mahajan, JL Asimit, ... Human molecular genetics 25 (10), 2070-2081, 2016 | 26 | 2016 |