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Vijay Kumar Kuchroo
Vijay Kumar Kuchroo
vkuchroo@evergrande.hms.harvard.edu
Adresse e-mail validée de evergrande.hms.harvard.edu
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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
E Bettelli, Y Carrier, W Gao, T Korn, TB Strom, M Oukka, HL Weiner, ...
Nature 441 (7090), 235-238, 2006
88612006
IL-17 and Th17 Cells
T Korn, E Bettelli, M Oukka, VK Kuchroo
Annual review of immunology 27, 485-517, 2009
65202009
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
S Deaglio, KM Dwyer, W Gao, D Friedman, A Usheva, A Erat, JF Chen, ...
The Journal of experimental medicine 204 (6), 1257-1265, 2007
28852007
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
Y Chen, VK Kuchroo, J Inobe, DA Hafler, HL Weiner
Science 265 (5176), 1237-1240, 1994
25851994
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
T Korn, E Bettelli, W Gao, A Awasthi, A Jäger, TB Strom, M Oukka, ...
Nature 448 (7152), 484-487, 2007
25122007
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
LM Francisco, VH Salinas, KE Brown, VK Vanguri, GJ Freeman, ...
Journal of Experimental Medicine 206 (13), 3015-3029, 2009
23602009
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
C Zhu, AC Anderson, A Schubart, H Xiong, J Imitola, SJ Khoury, ...
Nature immunology 6 (12), 1245-1252, 2005
22122005
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
K Sakuishi, L Apetoh, JM Sullivan, BR Blazar, VK Kuchroo, AC Anderson
Journal of Experimental Medicine 207 (10), 2187-2194, 2010
21702010
B7-1 and B7-2 costimulatory molecules activate differentially the Thl/Th2 developmental pathways: application to autoimmune disease therapy
JA Brown, AM Ranger, SS Zamvil, RA Sobel, HL Weiner
Cell 80, 707-718, 1995
21361995
TH-17 cells in the circle of immunity and autoimmunity
E Bettelli, M Oukka, VK Kuchroo
Nature immunology 8 (4), 345-350, 2007
20082007
Interleukin-17 and type 17 helper T cells
P Miossec, T Korn, VK Kuchroo
New England Journal of Medicine 361 (9), 888-898, 2009
19642009
Genetic and epigenetic fine mapping of causal autoimmune disease variants
KKH Farh, A Marson, J Zhu, M Kleinewietfeld, WJ Housley, S Beik, ...
Nature 518 (7539), 337-343, 2015
19572015
Lag-3, Tim-3, and TIGIT: co-inhibitory receptors with specialized functions in immune regulation
AC Anderson, N Joller, VK Kuchroo
Immunity 44 (5), 989-1004, 2016
19272016
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
L Monney, CA Sabatos, JL Gaglia, A Ryu, H Waldner, T Chernova, ...
Nature 415 (6871), 536-541, 2002
19202002
Induction and effector functions of TH17 cells
E Bettelli, T Korn, M Oukka, VK Kuchroo
Nature 453 (7198), 1051-1057, 2008
17162008
IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3 effector T cells
V Dardalhon, A Awasthi, H Kwon, G Galileos, W Gao, RA Sobel, ...
Nature immunology 9 (12), 1347-1355, 2008
14662008
Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients
J Fourcade, Z Sun, M Benallaoua, P Guillaume, IF Luescher, C Sander, ...
Journal of Experimental Medicine 207 (10), 2175-2186, 2010
14402010
IL-12 family cytokines: immunological playmakers
DAA Vignali, VK Kuchroo
Nature immunology 13 (8), 722-728, 2012
14052012
IL-21 and TGF-β are required for differentiation of human TH17 cells
L Yang, DE Anderson, C Baecher-Allan, WD Hastings, E Bettelli, M Oukka, ...
Nature 454 (7202), 350-352, 2008
12932008
Induction and molecular signature of pathogenic TH17 cells
Y Lee, A Awasthi, N Yosef, FJ Quintana, S Xiao, A Peters, C Wu, ...
Nature immunology 13 (10), 991-999, 2012
12832012
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