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Srinivas Chakravarthy
Srinivas Chakravarthy
Senior Scientist, Cytiva
Adresse e-mail validée de cytiva.com
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Reconstitution of nucleosome core particles from recombinant histones and DNA
PN Dyer, RS Edayathumangalam, CL White, Y Bao, S Chakravarthy, ...
Methods in enzymology 375, 23-44, 2003
8462003
Structural determinants for generating centromeric chromatin
BE Black, DR Foltz, S Chakravarthy, K Luger, VL Woods Jr, ...
Nature 430 (6999), 578-582, 2004
5102004
Structural characterization of the histone variant macroH2A
S Chakravarthy, SKY Gundimella, C Caron, PY Perche, JR Pehrson, ...
Molecular and cellular biology, 2005
2242005
Substrate-specific kinetics of Dicer-catalyzed RNA processing
S Chakravarthy, SH Sternberg, CA Kellenberger, JA Doudna
Journal of molecular biology 404 (3), 392-402, 2010
1782010
Structure and dynamic properties of nucleosome core particles
S Chakravarthy, YJ Park, J Chodaparambil, RS Edayathumangalam, ...
FEBS letters 579 (4), 895-898, 2005
1222005
The Histone Variant Macro-H2A Preferentially Forms “Hybrid Nucleosomes”*♦
S Chakravarthy, K Luger
Journal of Biological Chemistry 281 (35), 25522-25531, 2006
1092006
Structural coupling of the EF hand and C‐terminal GTPase domains in the mitochondrial protein Miro
JL Klosowiak, PJ Focia, S Chakravarthy, EC Landahl, DM Freymann, ...
EMBO reports 14 (11), 968-974, 2013
892013
Structural characterization of histone H2A variants
S Chakravarthy, Y Bao, VA Roberts, D Tremethick, K Luger
Cold Spring Harbor symposia on quantitative biology 69, 227-234, 2004
802004
Structure and dynamics of nucleosomal DNA
UM Muthurajan, YJ Park, RS Edayathumangalam, RK Suto, ...
Biopolymers: Original Research on Biomolecules 68 (4), 547-556, 2003
732003
Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A‐H2B histone dimer
CR Clapier, S Chakravarthy, C Petosa, C Fernández‐Tornero, K Luger, ...
Proteins: Structure, Function, and Bioinformatics 71 (1), 1-7, 2008
722008
The hTERT core promoter forms three parallel G-quadruplexes
RC Monsen, L DeLeeuw, WL Dean, RD Gray, TM Sabo, S Chakravarthy, ...
Nucleic acids research 48 (10), 5720-5734, 2020
712020
Sub-millisecond time-resolved SAXS using a continuous-flow mixer and X-ray microbeam
R Graceffa, RP Nobrega, RA Barrea, SV Kathuria, S Chakravarthy, ...
Journal of synchrotron radiation 20 (6), 820-825, 2013
712013
A multi-step nucleation process determines the kinetics of prion-like domain phase separation
EW Martin, TS Harmon, JB Hopkins, S Chakravarthy, JJ Incicco, P Schuck, ...
Nature communications 12 (1), 4513, 2021
692021
Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease
M Raththagala, MK Brewer, MW Parker, AR Sherwood, BK Wong, S Hsu, ...
Molecular cell 57 (2), 261-272, 2015
662015
Methods for analysis of size-exclusion chromatography–small-angle X-ray scattering and reconstruction of protein scattering
AW Malaby, S Chakravarthy, TC Irving, SV Kathuria, O Bilsel, ...
Journal of applied crystallography 48 (4), 1102-1113, 2015
632015
Impact of the N-terminal domain of STAT3 in STAT3-dependent transcriptional activity
T Hu, JE Yeh, L Pinello, J Jacob, S Chakravarthy, GC Yuan, R Chopra, ...
Molecular and cellular biology, 2015
612015
Microsecond barrier-limited chain collapse observed by time-resolved FRET and SAXS
SV Kathuria, C Kayatekin, R Barrea, E Kondrashkina, R Graceffa, L Guo, ...
Journal of molecular biology 426 (9), 1980-1994, 2014
602014
The Chd1 chromatin remodeler shifts nucleosomal DNA bidirectionally as a monomer
Y Qiu, RF Levendosky, S Chakravarthy, A Patel, GD Bowman, S Myong
Molecular cell 68 (1), 76-88. e6, 2017
582017
In vitro chromatin assembly: strategies and quality control
U Muthurajan, F Mattiroli, S Bergeron, K Zhou, Y Gu, S Chakravarthy, ...
Methods in enzymology 573, 3-41, 2016
512016
Decoupling nucleosome recognition from DNA binding dramatically alters the properties of the Chd1 chromatin remodeler
A Patel, S Chakravarthy, S Morrone, IM Nodelman, JN McKnight, ...
Nucleic Acids Research 41 (3), 1637-1648, 2013
492013
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