| A symbiosis expressed non‐ribosomal peptide synthetase from a mutualistic fungal endophyte of perennial ryegrass confers protection to the symbiotum from insect herbivory A Tanaka, BA Tapper, A Popay, EJ Parker, B Scott Molecular microbiology 57 (4), 1036-1050, 2005 | 375 | 2005 |
| On the temperature dependence of enzyme-catalyzed rates VL Arcus, EJ Prentice, JK Hobbs, AJ Mulholland, MW Van der Kamp, ... Biochemistry 55 (12), 1681-1688, 2016 | 283 | 2016 |
| Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates JK Hobbs, W Jiao, AD Easter, EJ Parker, LA Schipper, VL Arcus ACS chemical biology 8 (11), 2388-2393, 2013 | 207 | 2013 |
| The genetic basis for indole-diterpene chemical diversity in filamentous fungi S Saikia, MJ Nicholson, C Young, EJ Parker, B Scott Mycological Research 112 (2), 184-199, 2008 | 160 | 2008 |
| The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II … CJ Webby, HM Baker, JS Lott, EN Baker, EJ Parker Journal of Molecular Biology 354 (4), 927-939, 2005 | 105 | 2005 |
| Allosteric ACTion: the varied ACT domains regulating enzymes of amino-acid metabolism EJM Lang, PJ Cross, G Mittelstädt, GB Jameson, EJ Parker Current opinion in structural biology 29, 102-111, 2014 | 82 | 2014 |
| Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis CJ Webby, W Jiao, RD Hutton, NJ Blackmore, HM Baker, EN Baker, ... Journal of biological chemistry 285 (40), 30567-30576, 2010 | 78 | 2010 |
| Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline S Saikia, EJ Parker, A Koulman, B Scott FEBS letters 580 (6), 1625-1630, 2006 | 77 | 2006 |
| Substrate Ambiguity and Crystal Structure of Pyrococcus furiosus 3-Deoxy-d-arabino-heptulosonate-7-phosphate Synthase: An Ancestral 3-Deoxyald-2-ulosonate … LR Schofield, BF Anderson, ML Patchett, GE Norris, GB Jameson, ... Biochemistry 44 (36), 11950-11962, 2005 | 77 | 2005 |
| Defining paxilline biosynthesis in Penicillium paxilli: functional characterization of two cytochrome P450 monooxygenases S Saikia, EJ Parker, A Koulman, B Scott Journal of Biological Chemistry 282 (23), 16829-16837, 2007 | 76 | 2007 |
| Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis PJ Cross, RCJ Dobson, ML Patchett, EJ Parker Journal of Biological Chemistry 286 (12), 10216-10224, 2011 | 75 | 2011 |
| Molecular analysis of two cytochrome P450 monooxygenase genes required for paxilline biosynthesis in Penicillium paxilli, and effects of paxilline intermediates on … LK McMillan, RL Carr, CA Young, JW Astin, RGT Lowe, EJ Parker, ... Molecular genetics and genomics 270, 9-23, 2003 | 75 | 2003 |
| First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer EC Arturo, K Gupta, A Héroux, L Stith, PJ Cross, EJ Parker, PJ Loll, ... Proceedings of the National Academy of Sciences 113 (9), 2394-2399, 2016 | 68 | 2016 |
| Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism-and modeling-based design S Reichau, W Jiao, SR Walker, RD Hutton, EN Baker, EJ Parker Journal of Biological Chemistry 286 (18), 16197-16207, 2011 | 59 | 2011 |
| Indole-diterpene biosynthesis in ascomycetous fungi EJ Parker, DB Scott Handbook of industrial mycology, 424-445, 2004 | 58 | 2004 |
| Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain PJ Cross, TM Allison, RCJ Dobson, GB Jameson, EJ Parker Proceedings of the National Academy of Sciences 110 (6), 2111-2116, 2013 | 56 | 2013 |
| Selective inhibition of type II dehydroquinases M Frederickson, EJ Parker, AR Hawkins, JR Coggins, C Abell The Journal of organic chemistry 64 (8), 2612-2613, 1999 | 55 | 1999 |
| Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery W Jiao, RD Hutton, PJ Cross, GB Jameson, EJ Parker Journal of molecular biology 415 (4), 716-726, 2012 | 50 | 2012 |
| Identification of 4-Amino-4-deoxychorismate Synthase as the Molecular Target for the Antimicrobial Action of (6S)-6-Fluoroshikimate EMM Bulloch, MA Jones, EJ Parker, AP Osborne, E Stephens, GM Davies, ... Journal of the American Chemical Society 126 (32), 9912-9913, 2004 | 49 | 2004 |
| Expression, purification, and characterization of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Pyrococcus furiosus LR Schofield, ML Patchett, EJ Parker Protein expression and purification 34 (1), 17-27, 2004 | 48 | 2004 |
