| PD-1 blockade in tumors with mismatch-repair deficiency DT Le, JN Uram, H Wang, BR Bartlett, H Kemberling, AD Eyring, ... New England Journal of Medicine 372 (26), 2509-2520, 2015 | 9437 | 2015 |
| Cancer genome landscapes B Vogelstein, N Papadopoulos, VE Velculescu, S Zhou, LA Diaz Jr, ... science 339 (6127), 1546-1558, 2013 | 8506 | 2013 |
| An integrated genomic analysis of human glioblastoma multiforme DW Parsons, S Jones, X Zhang, JCH Lin, RJ Leary, P Angenendt, ... science 321 (5897), 1807-1812, 2008 | 6834 | 2008 |
| Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade DT Le, JN Durham, KN Smith, H Wang, BR Bartlett, LK Aulakh, S Lu, ... Science 357 (6349), 409-413, 2017 | 5980 | 2017 |
| Detection of circulating tumor DNA in early-and late-stage human malignancies C Bettegowda, M Sausen, RJ Leary, I Kinde, Y Wang, N Agrawal, ... Science translational medicine 6 (224), 224ra24-224ra24, 2014 | 4673 | 2014 |
| Circulating mutant DNA to assess tumor dynamics F Diehl, K Schmidt, MA Choti, K Romans, S Goodman, M Li, K Thornton, ... Nature medicine 14 (9), 985-990, 2008 | 2878 | 2008 |
| Liquid biopsies: genotyping circulating tumor DNA LA Diaz Jr, A Bardelli Journal of clinical oncology 32 (6), 579, 2014 | 2333 | 2014 |
| Detection and localization of surgically resectable cancers with a multi-analyte blood test JD Cohen, L Li, Y Wang, C Thoburn, B Afsari, L Danilova, C Douville, ... Science 359 (6378), 926-930, 2018 | 2330 | 2018 |
| Efficacy of pembrolizumab in patients with noncolorectal high microsatellite instability/mismatch repair–deficient cancer: results from the phase II KEYNOTE-158 study A Marabelle, DT Le, PA Ascierto, AM Di Giacomo, A De Jesus-Acosta, ... Journal of Clinical Oncology 38 (1), 1, 2020 | 2171 | 2020 |
| Fulminant myocarditis with combination immune checkpoint blockade DB Johnson, JM Balko, ML Compton, S Chalkias, J Gorham, Y Xu, ... New England Journal of Medicine 375 (18), 1749-1755, 2016 | 1978 | 2016 |
| The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers LA Diaz Jr, RT Williams, J Wu, I Kinde, JR Hecht, J Berlin, B Allen, I Bozic, ... Nature 486 (7404), 537-540, 2012 | 1939 | 2012 |
| Pembrolizumab in microsatellite-instability–high advanced colorectal cancer T André, KK Shiu, TW Kim, BV Jensen, LH Jensen, C Punt, D Smith, ... New England Journal of Medicine 383 (23), 2207-2218, 2020 | 1872 | 2020 |
| DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors Y Jiao, C Shi, BH Edil, RF De Wilde, DS Klimstra, A Maitra, RD Schulick, ... Science 331 (6021), 1199-1203, 2011 | 1821 | 2011 |
| TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal PJ Killela, ZJ Reitman, Y Jiao, C Bettegowda, N Agrawal, LA Diaz Jr, ... Proceedings of the National Academy of Sciences 110 (15), 6021-6026, 2013 | 1524 | 2013 |
| Detection and quantification of mutations in the plasma of patients with colorectal tumors F Diehl, M Li, D Dressman, Y He, D Shen, S Szabo, LA Diaz Jr, ... Proceedings of the National Academy of Sciences 102 (45), 16368-16373, 2005 | 1519 | 2005 |
| Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma S Jones, TL Wang, IM Shih, TL Mao, K Nakayama, R Roden, R Glas, ... Science 330 (6001), 228-231, 2010 | 1410 | 2010 |
| Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer J Tie, Y Wang, C Tomasetti, L Li, S Springer, I Kinde, N Silliman, M Tacey, ... Science translational medicine 8 (346), 346ra92-346ra92, 2016 | 1363 | 2016 |
| Immunotherapy in colorectal cancer: rationale, challenges and potential K Ganesh, ZK Stadler, A Cercek, RB Mendelsohn, J Shia, NH Segal, ... Nature reviews Gastroenterology & hepatology 16 (6), 361-375, 2019 | 1213 | 2019 |
| The colorectal microRNAome JM Cummins, Y He, RJ Leary, R Pagliarini, LA Diaz Jr, T Sjoblom, ... Proceedings of the National Academy of Sciences 103 (10), 3687-3692, 2006 | 1195 | 2006 |
| Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations DS Shin, JM Zaretsky, H Escuin-Ordinas, A Garcia-Diaz, S Hu-Lieskovan, ... Cancer discovery 7 (2), 188-201, 2017 | 1159 | 2017 |
Bert VogelsteinJohns HopkinsVerified email at jhmi.edu
