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Karen Bedard
Karen Bedard
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Year
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
K Bedard, KH Krause
Physiological reviews 87 (1), 245-313, 2007
77272007
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation
L Serrander, L Cartier, K Bedard, B Banfi, B Lardy, O Plastre, ...
Biochemical Journal 406 (1), 105-114, 2007
6822007
NOX family NADPH oxidases: not just in mammals
K Bedard, B Lardy, KH Krause
Biochimie 89 (9), 1107-1112, 2007
3462007
Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, and ERp57
K Bedard, E Szabo, M Michalak, M Opas
International review of cytology 245, 91-121, 2005
2032005
NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation
L Serrander, V Jaquet, K Bedard, O Plastre, O Hartley, S Arnaudeau, ...
Biochimie 89 (9), 1159-1167, 2007
1602007
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action
V Jaquet, J Marcoux, E Forest, KG Leidal, S McCormick, Y Westermaier, ...
British journal of pharmacology 164 (2b), 507-520, 2011
1442011
NOX5: from basic biology to signaling and disease
K Bedard, V Jaquet, KH Krause
Free Radical Biology and Medicine 52 (4), 725-734, 2012
1392012
Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci
T Aung, M Ozaki, MC Lee, U Schlötzer-Schrehardt, G Thorleifsson, ...
Nature genetics 49 (7), 993-1004, 2017
1362017
Phenotypic overlap between familial exudative vitreoretinopathy and microcephaly, lymphedema, and chorioretinal dysplasia caused by KIF11 mutations
JM Robitaille, RM Gillett, MA LeBlanc, D Gaston, M Nightingale, ...
JAMA ophthalmology 132 (12), 1393-1399, 2014
1152014
Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia
VL Bentley, CJ Veinotte, DP Corkery, JB Pinder, MA LeBlanc, K Bedard, ...
Haematologica 100 (1), 70, 2015
1032015
Mutation in pyrroline-5-carboxylate reductase 1 gene in families with cutis laxa type 2
DL Guernsey, H Jiang, SC Evans, M Ferguson, M Matsuoka, ...
The American Journal of Human Genetics 85 (1), 120-129, 2009
962009
Mutation in the gene encoding ubiquitin ligase LRSAM1 in patients with Charcot-Marie-Tooth disease
DL Guernsey, H Jiang, K Bedard, SC Evans, M Ferguson, M Matsuoka, ...
PLoS genetics 6 (8), e1001081, 2010
822010
Calnexin deficiency leads to dysmyelination
A Kraus, J Groenendyk, K Bedard, TA Baldwin, KH Krause, ...
Journal of biological chemistry 285 (24), 18928-18938, 2010
802010
NOX4 expression in human microglia leads to constitutive generation of reactive oxygen species and to constitutive IL-6 expression
B Li, K Bedard, S Sorce, B Hinz, M Dubois-Dauphin, KH Krause
Journal of innate immunity 1 (6), 570-581, 2009
782009
Germline Mutations in MAP3K6 Are Associated with Familial Gastric Cancer
D Gaston, S Hansford, C Oliveira, M Nightingale, H Pinheiro, ...
PLoS genetics 10 (10), e1004669, 2014
742014
Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation
K Bedard, H Attar, J Bonnefont, V Jaquet, C Borel, O Plastre, MJ Stasia, ...
Human mutation 30 (7), 1123-1133, 2009
742009
Endoplasmic reticulum stress in the absence of calnexin
H Coe, K Bedard, J Groenendyk, J Jung, M Michalak
Cell Stress and Chaperones 13, 497-507, 2008
652008
Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease
LP Bogdanik, JN Sleigh, C Tian, ME Samuels, K Bedard, KL Seburn, ...
Disease Models & Mechanisms 6 (3), 780-792, 2013
592013
NOX enzymes in immuno-inflammatory pathologies
KH Krause, K Bedard
Seminars in immunopathology 30, 193-194, 2008
462008
NADPH oxidase 1 deficiency alters Caveolin phosphorylation and angiotensin II–receptor localization in vascular smooth muscle
O Basset, C Deffert, M Foti, K Bedard, V Jaquet, E Ogier-Denis, ...
Antioxidants & redox signaling 11 (10), 2371-2384, 2009
452009
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