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Hisham Mazal
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Single-molecule FRET methods to study the dynamics of proteins at work
H Mazal, G Haran
Current opinion in biomedical engineering 12, 8-17, 2019
1062019
Direct observation of ultrafast large-scale dynamics of an enzyme under turnover conditions
HY Aviram, M Pirchi, H Mazal, Y Barak, I Riven, G Haran
Proceedings of the National Academy of Sciences 115 (13), 3243-3248, 2018
962018
Two closed ATP-and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn (II) EPR spectroscopic techniques
A Giannoulis, A Feintuch, Y Barak, H Mazal, S Albeck, T Unger, F Yang, ...
Proceedings of the National Academy of Sciences 117 (1), 395-404, 2020
572020
Tunable microsecond dynamics of an allosteric switch regulate the activity of a AAA+ disaggregation machine
H Mazal, M Iljina, Y Barak, N Elad, R Rosenzweig, P Goloubinoff, I Riven, ...
Nature communications 10 (1), 1438, 2019
502019
Ultrafast pore-loop dynamics in a AAA+ machine point to a Brownian-ratchet mechanism for protein translocation
H Mazal, M Iljina, I Riven, G Haran
SCIENCE ADVANCES 7 (36), 2021
32*2021
Long-range charge reorganization as an allosteric control signal in proteins
K Banerjee-Ghosh, S Ghosh, H Mazal, I Riven, G Haran, R Naaman
Journal of the American Chemical Society 142 (48), 20456-20462, 2020
302020
Self-supervised machine learning pushes the sensitivity limit in label-free detection of single proteins below 10 kDa
M Dahmardeh, H Mirzaalian Dastjerdi, H Mazal, H Köstler, V Sandoghdar
Nature Methods 20 (3), 442-447, 2023
262023
Effect of ligand binding on a protein with a complex folding landscape
H Mazal, H Aviram, I Riven, G Haran
Physical Chemistry Chemical Physics 20 (5), 3054-3062, 2018
262018
How fast are the motions of tertiary-structure elements in proteins?
G Haran, H Mazal
The Journal of Chemical Physics 153 (13), 2020
152020
Measuring protein stability in the GroEL chaperonin cage reveals massive destabilization
I Korobko, H Mazal, G Haran, A Horovitz
Elife 9, e56511, 2020
132020
Entropic inhibition: How the activity of a AAA+ machine is modulated by its substrate-binding domain
M Iljina, H Mazal, P Goloubinoff, I Riven, G Haran
ACS chemical biology 16 (4), 775-785, 2021
112021
Fast dynamics shape the function of the AAA+ machine ClpB: lessons from single‐molecule FRET spectroscopy
I Riven, H Mazal, M Iljina, G Haran
The FEBS journal 290 (14), 3496-3511, 2023
62023
Deciphering a hexameric protein complex with Angstrom optical resolution
H Mazal, FF Wieser, V Sandoghdar
Elife 11, e76308, 2022
52022
Single-molecule FRET probes allosteric effects on protein-translocating pore loops of a AAA+ machine
M Iljina, H Mazal, A Dayananda, Z Zhang, G Stan, I Riven, G Haran
Biophysical Journal 123 (3), 374-388, 2024
2024
Insights into protein structure using cryogenic light microscopy
H Mazal, FF Wieser, V Sandoghdar
Biochemical Society Transactions 51 (6), 2041-2059, 2023
2023
Breaking new ground in protein detection: Self-supervised machine learning and iSCAT enable label-free detection of single proteins below 10 kDa
M Dahmardeh, HM Dastjerdi, H Mazal, H Köstler, V Sandoghdar
Optical Molecular Probes, Imaging and Drug Delivery, JW2A. 3, 2023
2023
Urea as a Protein LID Opener: Overcoming Substrate Inhibition in Adenylate Kinase by Tuning Conformational Dynamics
D Scheerer, HY Aviram, H Mazal, I Riven, G Haran
Biophysical Journal 120 (3), 189a, 2021
2021
Single-molecule protein dynamics: From ligand binding effects on folding to function-related motions
H Mazal
Weizmann Institute of Science, 2019
2019
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Articles 1–18