Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin SL Gupton, KL Anderson, TP Kole, RS Fischer, A Ponti, ... The Journal of cell biology 168 (4), 619-631, 2005 | 327 | 2005 |
Deciphering the design of the tropomyosin molecule JH Brown, KH Kim, G Jun, NJ Greenfield, R Dominguez, N Volkmann, ... Proceedings of the National Academy of Sciences 98 (15), 8496-8501, 2001 | 318 | 2001 |
Inhibition of the Arp2/3 complex-nucleated actin polymerization and branch formation by tropomyosin L Blanchoin, TD Pollard, SE Hitchcock-DeGregori Current Biology 11 (16), 1300-1304, 2001 | 263 | 2001 |
Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge V DesMarais, I Ichetovkin, J Condeelis, SE Hitchcock-DeGregori Journal of cell science 115 (23), 4649-4660, 2002 | 221 | 2002 |
A systematic nomenclature for mammalian tropomyosin isoforms MA Geeves, SE Hitchcock-DeGregori, PW Gunning Journal of muscle research and cell motility 36, 147-153, 2015 | 207 | 2015 |
Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region T Palm, S Graboski, SE Hitchcock-DeGregori, NJ Greenfield Biophysical journal 81 (5), 2827-2837, 2001 | 175 | 2001 |
Altered actin and troponin binding of amino-terminal variants of chicken striated muscle alpha-tropomyosin expressed in Escherichia coli. SE Hitchcock-DeGregori, RW Heald Journal of Biological Chemistry 262 (20), 9730-9735, 1987 | 170 | 1987 |
Requirement of amino-terminal modification for striated muscle alpha-tropomyosin function. M Urbancikova, SE Hitchcock-DeGregori Journal of Biological Chemistry 269 (39), 24310-24315, 1994 | 169 | 1994 |
Solution NMR structure of the junction between tropomyosin molecules: implications for actin binding and regulation NJ Greenfield, YJ Huang, GVT Swapna, A Bhattacharya, B Rapp, A Singh, ... Journal of molecular biology 364 (1), 80-96, 2006 | 158 | 2006 |
The structure of the amino terminus of tropomyosin is critical for binding to actin in the absence and presence of troponin. RW Heald, SE Hitchcock-DeGregori Journal of Biological Chemistry 263 (11), 5254-5259, 1988 | 154 | 1988 |
The amino terminus of muscle tropomyosin is a major determinant for function. YJ Cho, J Liu, SE Hitchcock-DeGregori Journal of Biological Chemistry 265 (1), 538-545, 1990 | 152 | 1990 |
Local destabilization of the tropomyosin coiled coil gives the molecular flexibility required for actin binding A Singh, SE Hitchcock-DeGregori Biochemistry 42 (48), 14114-14121, 2003 | 120 | 2003 |
Tropomyosin: function follows structure SE Hitchcock-DeGregori Tropomyosin, 60-72, 2008 | 118 | 2008 |
The Structure of the N-Terminus of Striated Muscle α-Tropomyosin in a Chimeric Peptide: Nuclear Magnetic Resonance Structure and Circular Dichroism Studies, NJ Greenfield, GT Montelione, RS Farid, SE Hitchcock-DeGregori Biochemistry 37 (21), 7834-7843, 1998 | 118 | 1998 |
The ends of tropomyosin are major determinants of actin affinity and myosin subfragment 1-induced binding to F-actin in the open state J Moraczewska, K Nicholson-Flynn, SE Hitchcock-DeGregori Biochemistry 38 (48), 15885-15892, 1999 | 114 | 1999 |
Tropomyosin has discrete actin-binding sites with sevenfold and fourteenfold periodicities SE Hitchcock-DeGregori, TA Varnell Journal of molecular biology 214 (4), 885-896, 1990 | 110 | 1990 |
Mapping the Functional Domains within the Carboxyl Terminus of α-Tropomyosin Encoded by the Alternatively Spliced Ninth Exon (∗) RL Hammell, SE Hitchcock-DeGregori Journal of Biological Chemistry 271 (8), 4236-4242, 1996 | 100 | 1996 |
The stability of tropomyosin, a two-stranded coiled-coil protein, is primarily a function of the hydrophobicity of residues at the helix-helix interface NJ Greenfield, SE Hitchcock-DeGregori Biochemistry 34 (51), 16797-16805, 1995 | 97 | 1995 |
Dual requirement for flexibility and specificity for binding of the coiled-coil tropomyosin to its target, actin A Singh, SE Hitchcock-DeGregori Structure 14 (1), 43-50, 2006 | 94 | 2006 |
Effects of two familial hypertrophic cardiomyopathy-causing mutations on α-tropomyosin structure and function N Golitsina, Y An, NJ Greenfield, L Thierfelder, K Iizuka, JG Seidman, ... Biochemistry 36 (15), 4637-4642, 1997 | 92 | 1997 |