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Sarah E. Hitchcock-DeGregori
Sarah E. Hitchcock-DeGregori
professor emeritus, Robert wood johnson med sch
Verified email at rwjms.rutgers.edu
Title
Cited by
Cited by
Year
Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin
SL Gupton, KL Anderson, TP Kole, RS Fischer, A Ponti, ...
The Journal of cell biology 168 (4), 619-631, 2005
3272005
Deciphering the design of the tropomyosin molecule
JH Brown, KH Kim, G Jun, NJ Greenfield, R Dominguez, N Volkmann, ...
Proceedings of the National Academy of Sciences 98 (15), 8496-8501, 2001
3182001
Inhibition of the Arp2/3 complex-nucleated actin polymerization and branch formation by tropomyosin
L Blanchoin, TD Pollard, SE Hitchcock-DeGregori
Current Biology 11 (16), 1300-1304, 2001
2632001
Spatial regulation of actin dynamics: a tropomyosin-free, actin-rich compartment at the leading edge
V DesMarais, I Ichetovkin, J Condeelis, SE Hitchcock-DeGregori
Journal of cell science 115 (23), 4649-4660, 2002
2212002
A systematic nomenclature for mammalian tropomyosin isoforms
MA Geeves, SE Hitchcock-DeGregori, PW Gunning
Journal of muscle research and cell motility 36, 147-153, 2015
2072015
Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region
T Palm, S Graboski, SE Hitchcock-DeGregori, NJ Greenfield
Biophysical journal 81 (5), 2827-2837, 2001
1752001
Altered actin and troponin binding of amino-terminal variants of chicken striated muscle alpha-tropomyosin expressed in Escherichia coli.
SE Hitchcock-DeGregori, RW Heald
Journal of Biological Chemistry 262 (20), 9730-9735, 1987
1701987
Requirement of amino-terminal modification for striated muscle alpha-tropomyosin function.
M Urbancikova, SE Hitchcock-DeGregori
Journal of Biological Chemistry 269 (39), 24310-24315, 1994
1691994
Solution NMR structure of the junction between tropomyosin molecules: implications for actin binding and regulation
NJ Greenfield, YJ Huang, GVT Swapna, A Bhattacharya, B Rapp, A Singh, ...
Journal of molecular biology 364 (1), 80-96, 2006
1582006
The structure of the amino terminus of tropomyosin is critical for binding to actin in the absence and presence of troponin.
RW Heald, SE Hitchcock-DeGregori
Journal of Biological Chemistry 263 (11), 5254-5259, 1988
1541988
The amino terminus of muscle tropomyosin is a major determinant for function.
YJ Cho, J Liu, SE Hitchcock-DeGregori
Journal of Biological Chemistry 265 (1), 538-545, 1990
1521990
Local destabilization of the tropomyosin coiled coil gives the molecular flexibility required for actin binding
A Singh, SE Hitchcock-DeGregori
Biochemistry 42 (48), 14114-14121, 2003
1202003
Tropomyosin: function follows structure
SE Hitchcock-DeGregori
Tropomyosin, 60-72, 2008
1182008
The Structure of the N-Terminus of Striated Muscle α-Tropomyosin in a Chimeric Peptide:  Nuclear Magnetic Resonance Structure and Circular Dichroism Studies,
NJ Greenfield, GT Montelione, RS Farid, SE Hitchcock-DeGregori
Biochemistry 37 (21), 7834-7843, 1998
1181998
The ends of tropomyosin are major determinants of actin affinity and myosin subfragment 1-induced binding to F-actin in the open state
J Moraczewska, K Nicholson-Flynn, SE Hitchcock-DeGregori
Biochemistry 38 (48), 15885-15892, 1999
1141999
Tropomyosin has discrete actin-binding sites with sevenfold and fourteenfold periodicities
SE Hitchcock-DeGregori, TA Varnell
Journal of molecular biology 214 (4), 885-896, 1990
1101990
Mapping the Functional Domains within the Carboxyl Terminus of α-Tropomyosin Encoded by the Alternatively Spliced Ninth Exon (∗)
RL Hammell, SE Hitchcock-DeGregori
Journal of Biological Chemistry 271 (8), 4236-4242, 1996
1001996
The stability of tropomyosin, a two-stranded coiled-coil protein, is primarily a function of the hydrophobicity of residues at the helix-helix interface
NJ Greenfield, SE Hitchcock-DeGregori
Biochemistry 34 (51), 16797-16805, 1995
971995
Dual requirement for flexibility and specificity for binding of the coiled-coil tropomyosin to its target, actin
A Singh, SE Hitchcock-DeGregori
Structure 14 (1), 43-50, 2006
942006
Effects of two familial hypertrophic cardiomyopathy-causing mutations on α-tropomyosin structure and function
N Golitsina, Y An, NJ Greenfield, L Thierfelder, K Iizuka, JG Seidman, ...
Biochemistry 36 (15), 4637-4642, 1997
921997
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