| Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein DJ Rodi, RW Janes, HJ Sanganee, RA Holton, BA Wallace, L Makowski Journal of molecular biology 285 (1), 197-203, 1999 | 334 | 1999 |
| An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes JS Albert, N Blomberg, AL Breeze, AJH Brown, JN Burrows, PD Edwards, ... Current Topics in Medicinal Chemistry 7 (16), 1600-1629, 2007 | 148 | 2007 |
| 4-Substituted-5, 5-dimethyl oxazolidin-2-ones as effective chiral auxiliaries for enolate alkylations and Michael additions SG Davies, HJ Sanganee Tetrahedron: Asymmetry 6 (3), 671-674, 1995 | 146 | 1995 |
| Asymmetric alkylations using SuperQuat auxiliaries—an investigation into the synthesis and stability of enolates derived from 5, 5-disubstituted oxazolidin-2-ones SD Bull, SG Davies, S Jones, HJ Sanganee Journal of the Chemical Society, Perkin Transactions 1, 387-398, 1999 | 123 | 1999 |
| The ‘SuperQuat’(R)-4-phenyl-5, 5-dimethyl oxazolidin-2-one as an effective chiral auxiliary for conjugate additions: Asymmetric synthesis of (−)-Aplysillamide B SG Davies, HJ Sanganee, P Szolcsanyi Tetrahedron 55 (11), 3337-3354, 1999 | 100 | 1999 |
| One-pot catalytic enantioselective synthesis of tetrahydropyridines via a nitro-Mannich/hydroamination cascade DM Barber, HJ Sanganee, DJ Dixon Organic letters 14 (20), 5290-5293, 2012 | 75 | 2012 |
| One-pot nitro-Mannich/hydroamination cascades for the direct synthesis of 2, 5-disubstituted pyrroles using base and gold catalysis DM Barber, H Sanganee, DJ Dixon Chemical communications 47 (15), 4379-4381, 2011 | 67 | 2011 |
| Cathepsin C inhibitors: property optimization and identification of a clinical candidate M Furber, AK Tiden, P Gardiner, A Mete, R Ford, I Millichip, L Stein, ... Journal of Medicinal Chemistry 57 (6), 2357-2367, 2014 | 65 | 2014 |
| A Practical procedure for the multigram synthesis of the superquat chiral auxiliaries SD Bull, SG Davies, S Jones, MEC Polywka, RS Prasad, HJ Sanganee Synlett 1998 (05), 519-521, 1998 | 59 | 1998 |
| Discovery of potent CRTh2 (DP2) receptor antagonists TN Birkinshaw, SJ Teague, C Beech, RV Bonnert, S Hill, A Patel, ... Bioorganic & medicinal chemistry letters 16 (16), 4287-4290, 2006 | 55 | 2006 |
| One-pot asymmetric nitro-mannich/hydroamination cascades for the synthesis of pyrrolidine derivatives: combining organocatalysis and gold catalysis DM Barber, A Ďuriš, AL Thompson, HJ Sanganee, DJ Dixon ACS catalysis 4 (2), 634-638, 2014 | 54 | 2014 |
| SuperQuat N-acyl-5, 5-dimethyloxazolidin-2-ones for the asymmetric synthesis of α-alkyl and β-alkyl aldehydes SD Bull, SG Davies, RL Nicholson, HJ Sanganee, AD Smith Organic & biomolecular chemistry 1 (16), 2886-2899, 2003 | 53 | 2003 |
| Synthesis of 5-substituted-3, 3-dimethyl-2-pyrrolidinones:“quat” chiral auxiliaries SG Davies, GJM Doisneau, JC Prodger, HJ Sanganee Tetrahedron letters 35 (15), 2369-2372, 1994 | 53 | 1994 |
| Pioneering government-sponsored drug repositioning collaborations: progress and learning DE Frail, M Brady, KJ Escott, A Holt, HJ Sanganee, MN Pangalos, ... Nature Reviews Drug Discovery 14 (12), 833-841, 2015 | 51 | 2015 |
| Potent dual inhibitors of TORC1 and TORC2 complexes (KU-0063794 and KU-0068650) demonstrate in vitro and ex vivo anti-keloid scar activity F Syed, HJ Sanganee, A Bahl, A Bayat Journal of Investigative Dermatology 133 (5), 1340-1350, 2013 | 45 | 2013 |
| Substituted indole-1-acetic acids as potent and selective CRTH2 antagonists—discovery of AZD1981 T Luker, R Bonnert, S Brough, AR Cook, MR Dickinson, I Dougall, ... Bioorganic & medicinal chemistry letters 21 (21), 6288-6292, 2011 | 42 | 2011 |
| Synthesis and utility of the 3, 3-dimethyl-5-substituted-2-pyrrolidinone ‘Quat’chiral auxiliary SG Davies, DJ Dixon, GJM Doisneau, JC Prodger, HJ Sanganee Tetrahedron: Asymmetry 13 (6), 647-658, 2002 | 42 | 2002 |
| SuperQuat,(S)-4-benzyl-5, 5-dimethyl-oxazolidin-2-one for the asymmetric synthesis of α-substituted-aldehydes SD Bull, SG Davies, RL Nicholson, HJ Sanganee, AD Smith Tetrahedron: Asymmetry 11 (17), 3475-3479, 2000 | 40 | 2000 |
| Asymmetric aldol and alkylation reactions mediated by the “quat” chiral auxiliary (R)-(−)-5-methyl-3, 3-dimethyl-2-pyrrolidinone SG Davies, GJM Doisneau, JC Prodger, HJ Sanganee Tetrahedron letters 35 (15), 2373-2376, 1994 | 39 | 1994 |
| Systems and methods for digital predictive disease exacerbation and pre-emptive treatment R Kakkar, C Collier, H Sanganee US Patent App. 14/863,876, 2016 | 38 | 2016 |
