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George H. Caughey
George H. Caughey
Emeritus Professor of Medicine, UCSF
Verified email at ucsf.edu
Title
Cited by
Cited by
Year
Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis
LM Coussens, WW Raymond, G Bergers, M Laig-Webster, O Behrendtsen, ...
Genes & development 13 (11), 1382-1397, 1999
11961999
Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism
M Steinhoff, N Vergnolle, SH Young, M Tognetto, S Amadesi, HS Ennes, ...
Nature medicine 6 (2), 151-158, 2000
11002000
Mast cell tryptases and chymases in inflammation and host defense
GH Caughey
Immunological reviews 217 (1), 141-154, 2007
5562007
Mast cell tryptase is a mitogen for cultured fibroblasts.
SJ Ruoss, T Hartmann, GH Caughey
The Journal of clinical investigation 88 (2), 493-499, 1991
4811991
Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells.
CP Sommerhoff, JA Nadel, CB Basbaum, GH Caughey
The Journal of clinical investigation 85 (3), 682-689, 1990
4651990
Substance P and vasoactive intestinal peptide degradation by mast cell tryptase and chymase.
GH Caughey, F Leidig, NF Viro, JA Nadel
Journal of Pharmacology and Experimental Therapeutics 244 (1), 133-137, 1988
4071988
Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.
CU Corvera, O Déry, K McConalogue, SK Böhm, LM Khitin, GH Caughey, ...
The Journal of clinical investigation 100 (6), 1383-1393, 1997
3601997
Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number
JJ Lyons, X Yu, JD Hughes, QT Le, A Jamil, Y Bai, N Ho, M Zhao, Y Liu, ...
Nature genetics 48 (12), 1564-1569, 2016
3132016
Accumulation of intraepithelial mast cells with a unique protease phenotype in TH2-high asthma
RH Dougherty, SS Sidhu, K Raman, M Solon, OD Solberg, GH Caughey, ...
Journal of Allergy and Clinical Immunology 125 (5), 1046-1053. e8, 2010
3122010
Proteinase‐activated receptor‐2 in human skin: tissue distribution and activation of keratinocytes by mast cell tryptase
M Steinhoff, CU Corvera, MS Thoma, W Kong, BE McAlpine, GH Caughey, ...
Experimental dermatology 8 (4), 282-294, 1999
2881999
Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.
P Vanderslice, SM Ballinger, EK Tam, SM Goldstein, CS Craik, ...
Proceedings of the National Academy of Sciences 87 (10), 3811-3815, 1990
2881990
Degradation of airway neuropeptides by human lung tryptase
EK Tam, GH Caughey
Am J Respir Cell Mol Biol 3 (1), 27-32, 1990
2761990
Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor
JA Auchampach, X Jin, TC Wan, GH Caughey, J Linden
Molecular pharmacology 52 (5), 846-860, 1997
2501997
Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice
PJ Wolters, CTN Pham, DJ Muilenburg, TJ Ley, GH Caughey
Journal of Biological Chemistry 276 (21), 18551-18556, 2001
2442001
Thrombin and mast cell tryptase regulate guinea‐pig myenteric neurons through proteinase‐activated receptors‐1 and− 2
CU Corvera, O Déry, K McConalogue, P Gamp, M Thoma, B Al‐Ani, ...
The Journal of physiology 517 (3), 741-756, 1999
2291999
Angiotensin II generation by mast cell α-and β-chymases
GH Caughey, WW Raymond, PJ Wolters
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2000
2262000
Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs.
K Sekizawa, GH Caughey, SC Lazarus, WM Gold, JA Nadel
The Journal of clinical investigation 83 (1), 175-179, 1989
2161989
Clustering of activating mutations in c-KIT’s juxtamembrane coding region in canine mast cell neoplasms
Y Ma, BJ Longley, X Wang, JL Blount, K Langley, GH Caughey
Journal of Investigative Dermatology 112 (2), 165-170, 1999
2111999
Dog mast cell α-chymase activates progelatinase B by cleaving the Phe88-Gln89 and Phe91-Glu92 bonds of the catalytic domain
KC Fang, WW Raymond, JL Blount, GH Caughey
Journal of Biological Chemistry 272 (41), 25628-25635, 1997
2061997
Mast cell proteases as protective and inflammatory mediators
GH Caughey
Mast Cell Biology: Contemporary and Emerging Topics, 212-234, 2011
2052011
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