| Challenges to curing primary brain tumours K Aldape, KM Brindle, L Chesler, R Chopra, A Gajjar, MR Gilbert, ... Nature reviews Clinical oncology 16 (8), 509-520, 2019 | 674 | 2019 |
| The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo VJ Weston, CE Oldreive, A Skowronska, DG Oscier, G Pratt, MJS Dyer, ... Blood, The Journal of the American Society of Hematology 116 (22), 4578-4587, 2010 | 346 | 2010 |
| Characterization of a progenitor cell population in childhood T-cell acute lymphoblastic leukemia CV Cox, HM Martin, PR Kearns, P Virgo, RS Evely, A Blair Blood 109 (2), 674-682, 2007 | 197 | 2007 |
| Expression of CD133 on leukemia-initiating cells in childhood ALL CV Cox, P Diamanti, RS Evely, PR Kearns, A Blair Blood, The Journal of the American Society of Hematology 113 (14), 3287-3296, 2009 | 187 | 2009 |
| Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target F Mussai, S Egan, J Higginbotham-Jones, T Perry, A Beggs, E Odintsova, ... Blood, The Journal of the American Society of Hematology 125 (15), 2386-2396, 2015 | 182 | 2015 |
| The COVID‐19 pandemic: a rapid global response for children with cancer from SIOP, COG, SIOP‐E, SIOP‐PODC, IPSO, PROS, CCI, and St Jude Global M Sullivan, E Bouffet, C Rodriguez‐Galindo, S Luna‐Fineman, MS Khan, ... Pediatric blood & cancer 67 (7), e28409, 2020 | 180 | 2020 |
| Defining and listing very rare cancers of paediatric age: consensus of the Joint Action on Rare Cancers in cooperation with the European Cooperative Study Group for Pediatric … A Ferrari, IB Brecht, G Gatta, DT Schneider, D Orbach, G Cecchetto, ... European journal of cancer 110, 120-126, 2019 | 143 | 2019 |
| Dasatinib in children and adolescents with relapsed or refractory leukemia: results of the CA180-018 phase I dose-escalation study of the Innovative Therapies for Children with … CM Zwaan, C Rizzari, F Mechinaud, DL Lancaster, T Lehrnbecher, ... Journal of Clinical Oncology 31 (19), 2460-2468, 2013 | 109 | 2013 |
| Severity of COVID-19 in children with cancer: report from the United Kingdom Paediatric Coronavirus Cancer Monitoring Project GC Millen, R Arnold, JB Cazier, H Curley, RG Feltbower, A Gamble, ... British journal of cancer 124 (4), 754-759, 2021 | 108 | 2021 |
| Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy–results of a United Kingdom phase II trial (CNS 2007 04) S Bailey, A Howman, K Wheatley, D Wherton, N Boota, B Pizer, D Fisher, ... European journal of cancer 49 (18), 3856-3862, 2013 | 104 | 2013 |
| Dasatinib in pediatric patients with chronic myeloid leukemia in chronic phase: results from a phase II trial L Gore, PR Kearns, ML de Martino, Lee, CA De Souza, Y Bertrand, ... Journal of Clinical Oncology 36 (13), 1330-1338, 2018 | 96 | 2018 |
| The EBV oncogene LMP1 protects lymphoma cells from cell death through the collagen-mediated activation of DDR1 FZ Cader, M Vockerodt, S Bose, E Nagy, MA Brundler, P Kearns, ... Blood, The Journal of the American Society of Hematology 122 (26), 4237-4245, 2013 | 95 | 2013 |
| BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia D Da Costa, A Agathanggelou, T Perry, V Weston, E Petermann, ... Blood cancer journal 3 (7), e126-e126, 2013 | 95 | 2013 |
| Gene expression profiling identifies different sub-types of retinoblastoma G Kapatai, MA Brundler, H Jenkinson, P Kearns, M Parulekar, AC Peet, ... British journal of cancer 109 (2), 512-525, 2013 | 85 | 2013 |
| USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status A Agathanggelou, E Smith, NJ Davies, M Kwok, A Zlatanou, CE Oldreive, ... Blood, The Journal of the American Society of Hematology 130 (2), 156-166, 2017 | 76 | 2017 |
| The ability to cross the blood–cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts MTS Williams, YM Yousafzai, A Elder, K Rehe, S Bomken, ... Blood, The Journal of the American Society of Hematology 127 (16), 1998-2006, 2016 | 75 | 2016 |
| The role of the ‘innovative therapies for children with cancer’(ITCC) European consortium CM Zwaan, P Kearns, H Caron, A Verschuur, R Riccardi, J Boos, F Doz, ... Cancer treatment reviews 36 (4), 328-334, 2010 | 73 | 2010 |
| Examining the immunological effects of COVID-19 vaccination in patients with conditions potentially leading to diminished immune response capacity–the OCTAVE trial P Kearns, S Siebert, C Gaskell, A Kirkham, S Pirrie, S Bowden, ... | 72 | 2021 |
| Targeting the arginine metabolic brake enhances immunotherapy for leukaemia F Mussai, R Wheat, E Sarrou, S Booth, V Stavrou, L Fultang, T Perry, ... International journal of cancer 145 (8), 2201-2208, 2019 | 70 | 2019 |
| Implementation of mechanism of action biology-driven early drug development for children with cancer ADJ Pearson, R Herold, R Rousseau, C Copland, B Bradley-Garelik, ... European Journal of Cancer 62, 124-131, 2016 | 65 | 2016 |
