Azucena Salas
Azucena Salas
Investigator, IDIBAPS
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Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial
S Vermeire, S O'Byrne, M Keir, M Williams, TT Lu, JC Mansfield, CA Lamb, ...
The Lancet 384 (9940), 309-318, 2014
JAK–STAT pathway targeting for the treatment of inflammatory bowel disease
A Salas, C Hernandez-Rocha, M Duijvestein, W Faubion, D McGovern, ...
Nature reviews Gastroenterology & hepatology 17 (6), 323-337, 2020
The primacy of affinity over clustering in regulation of adhesiveness of the integrin αLβ2
M Kim, CV Carman, W Yang, A Salas, TA Springer
The Journal of cell biology 167 (6), 1241-1253, 2004
Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1
CV Carman, CD Jun, A Salas, TA Springer
The Journal of Immunology 171 (11), 6135-6144, 2003
Rolling adhesion through an extended conformation of integrin αLβ2 and relation to α I and β I-like domain interaction
A Salas, M Shimaoka, AN Kogan, C Harwood, UH von Andrian, ...
Immunity 20 (4), 393-406, 2004
Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations
N Planell, JJ Lozano, R Mora-Buch, MC Masamunt, M Jimeno, I Ordás, ...
Gut 62 (7), 967-976, 2013
VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice
A Soriano, A Salas, A Salas, M Sans, M Gironella, M Elena, DC Anderson, ...
Laboratory investigation 80 (10), 1541-1551, 2000
Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster
JF Chen, A Salas, TA Springer
Nature Structural & Molecular Biology 10 (12), 995-1001, 2003
CD1d function is regulated by microsomal triglyceride transfer protein
S Brozovic, T Nagaishi, M Yoshida, S Betz, A Salas, D Chen, A Kaser, ...
Nature medicine 10 (5), 535-539, 2004
Alterations in the epithelial stem cell compartment could contribute to permanent changes in the mucosa of patients with ulcerative colitis
I Dotti, R Mora-Buch, E Ferrer-Picón, N Planell, P Jung, MC Masamunt, ...
Gut 66 (12), 2069-2079, 2017
Heparin attenuates TNF-α induced inflammatory response through a CD11b dependent mechanism
A Salas, M Sans, A Soriano, JC Reverter, DC Anderson, JM Pique, ...
Gut 47 (1), 88-96, 2000
Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells
SK Dougan, A Salas, P Rava, A Agyemang, A Kaser, J Morrison, ...
The Journal of experimental medicine 202 (4), 529-539, 2005
Small molecule integrin antagonists that bind to the β2 subunit I-like domain and activate signals in one direction and block them in the other
M Shimaoka, A Salas, W Yang, G Weitz-Schmidt, TA Springer
Immunity 19 (3), 391-402, 2003
Importance of force linkage in mechanochemistry of adhesion receptors
NS Astrof, A Salas, M Shimaoka, JF Chen, TA Springer
Biochemistry 45 (50), 15020-15028, 2006
Effects of steroid treatment on activation of nuclear factor κB in patients with inflammatory bowel disease
E Ardite, J Panes, M Miranda, A Salas, JI Elizalde, M Sans, Y Arce, ...
British journal of pharmacology 124 (3), 431-433, 1998
Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy
RF Leal, N Planell, R Kajekar, JJ Lozano, I Ordás, I Dotti, M Esteller, ...
Gut 64 (2), 233-242, 2015
Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin lymphocyte function-associated antigen-1
A Salas, M Shimaoka, S Chen, CV Carman, T Springer
Journal of Biological Chemistry 277 (52), 50255-50262, 2002
Role of P-selectin and ICAM-1 in pancreatitis-induced lung inflammation in rats: significance of oxidative stress
E Folch, A Salas, J Panés, E Gelpí, J Roselló-Catafau, DC Anderson, ...
Annals of surgery 230 (6), 792, 1999
Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring
W Yang, M Shimaoka, A Salas, J Takagi, TA Springer
Proceedings of the National Academy of Sciences 101 (9), 2906-2911, 2004
A gut microbial mimic that hijacks diabetogenic autoreactivity to suppress colitis
RH Nanjundappa, F Ronchi, J Wang, X Clemente-Casares, ...
Cell 171 (3), 655-667. e17, 2017
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