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Purvesh Khatri
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Ten years of pathway analysis: current approaches and outstanding challenges
P Khatri, M Sirota, AJ Butte
PLoS computational biology 8 (2), e1002375, 2012
15572012
A systems biology approach for pathway level analysis
S Draghici, P Khatri, AL Tarca, K Amin, A Done, C Voichita, C Georgescu, ...
Genome research 17 (10), 1537-1545, 2007
11972007
Ontological analysis of gene expression data: current tools, limitations, and open problems
P Khatri, S Drăghici
Bioinformatics 21 (18), 3587-3595, 2005
10702005
A novel signaling pathway impact analysis
AL Tarca, S Draghici, P Khatri, SS Hassan, P Mittal, J Kim, CJ Kim, ...
Bioinformatics 25 (1), 75-82, 2009
10492009
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
PS Arunachalam, F Wimmers, CKP Mok, RAPM Perera, M Scott, T Hagan, ...
Science 369 (6508), 1210-1220, 2020
7602020
Reliability and reproducibility issues in DNA microarray measurements
S Draghici, P Khatri, AC Eklund, Z Szallasi
TRENDS in Genetics 22 (2), 101-109, 2006
7442006
Global functional profiling of gene expression
S Draghici, P Khatri, RP Martins, GC Ostermeier, SA Krawetz
Genomics 81 (2), 98-104, 2003
7212003
Spermatozoal RNA profiles of normal fertile men
GC Ostermeier, DJ Dix, D Miller, P Khatri, SA Krawetz
The Lancet 360 (9335), 772-777, 2002
5722002
Profiling gene expression using onto-express
P Khatri, S Draghici, GC Ostermeier, SA Krawetz
Genomics 79 (2), 266-270, 2002
5592002
Cell type–specific gene expression differences in complex tissues
SS Shen-Orr, R Tibshirani, P Khatri, DL Bodian, F Staedtler, NM Perry, ...
Nature methods 7 (4), 287-289, 2010
5042010
NetPath: a public resource of curated signal transduction pathways
K Kandasamy, SS Mohan, R Raju, S Keerthikumar, GSS Kumar, ...
Genome biology 11 (1), 1-9, 2010
4782010
Onto-tools, the toolkit of the modern biologist: onto-express, onto-compare, onto-design and onto-translate
S Draghici, P Khatri, P Bhavsar, A Shah, SA Krawetz, MA Tainsky
Nucleic acids research 31 (13), 3775-3781, 2003
4382003
Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis
TE Sweeney, L Braviak, CM Tato, P Khatri
The Lancet Respiratory Medicine 4 (3), 213-224, 2016
3412016
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
PK Mazur, N Reynoird, P Khatri, PWTC Jansen, AW Wilkinson, S Liu, ...
Nature 510 (7504), 283-287, 2014
3412014
A Drug Repositioning Approach Identifies Tricyclic Antidepressants as Inhibitors of Small Cell Lung Cancer and Other Neuroendocrine TumorsTricyclic Antidepressants Inhibit SCLC
NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ...
Cancer discovery 3 (12), 1364-1377, 2013
3372013
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, ...
Nature medicine 21 (10), 1163-1171, 2015
3252015
A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set
TE Sweeney, A Shidham, HR Wong, P Khatri
Science translational medicine 7 (287), 287ra71-287ra71, 2015
2752015
Robust classification of bacterial and viral infections via integrated host gene expression diagnostics
TE Sweeney, HR Wong, P Khatri
Science translational medicine 8 (346), 346ra91-346ra91, 2016
2552016
A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring
A Alpert, Y Pickman, M Leipold, Y Rosenberg-Hasson, X Ji, R Gaujoux, ...
Nature medicine 25 (3), 487-495, 2019
2492019
Single-cell chromatin modification profiling reveals increased epigenetic variations with aging
P Cheung, F Vallania, HC Warsinske, M Donato, S Schaffert, SE Chang, ...
Cell 173 (6), 1385-1397. e14, 2018
2262018
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