| Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas C Palles, JB Cazier, KM Howarth, E Domingo, AM Jones, P Broderick, ... Nature genetics 45 (2), 136-144, 2013 | 1079 | 2013 |
| Replication stress links structural and numerical cancer chromosomal instability RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ... Nature 494 (7438), 492-496, 2013 | 901 | 2013 |
| A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3 IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ... Nature genetics 40 (5), 623-630, 2008 | 653 | 2008 |
| A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk P Broderick, L Carvajal-Carmona, AM Pittman, E Webb, K Howarth, ... Nature genetics 39 (11), 1315-1317, 2007 | 610 | 2007 |
| Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer L Carvajal-Carmona, K Howarth, E Jaeger, SL Spain, A Walther, ... Nature genetics 40 (12), 1426-1435, 2008 | 605 | 2008 |
| Deep learning for prediction of colorectal cancer outcome: a discovery and validation study OJ Skrede, S De Raedt, A Kleppe, TS Hveem, K Liestøl, J Maddison, ... The Lancet 395 (10221), 350-360, 2020 | 432 | 2020 |
| BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing E Domingo, P Laiho, M Ollikainen, M Pinto, L Wang, AJ French, J Westra, ... Journal of medical genetics 41 (9), 664-668, 2004 | 430 | 2004 |
| Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26. 2, 12q13. 13 and 20q13. 33 RS Houlston, J Cheadle, SE Dobbins, A Tenesa, AM Jones, K Howarth, ... Nature genetics 42 (11), 973-977, 2010 | 425 | 2010 |
| DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer DN Church, SEW Briggs, C Palles, E Domingo, SJ Kearsey, JM Grimes, ... Human molecular genetics 22 (14), 2820-2828, 2013 | 391 | 2013 |
| Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13. 3 influence colorectal cancer risk E Jaeger, E Webb, K Howarth, L Carvajal-Carmona, A Rowan, ... Nature genetics 40 (1), 26-28, 2008 | 352 | 2008 |
| The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial A Huijbers, R Tollenaar, GW v Pelt, ECM Zeestraten, S Dutton, ... Annals of oncology 24 (1), 179-185, 2013 | 302 | 2013 |
| KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression C Oliveira, S Velho, C Moutinho, A Ferreira, A Preto, E Domingo, ... Oncogene 26 (1), 158-163, 2007 | 282 | 2007 |
| Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ... The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016 | 281 | 2016 |
| Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk MG Dunlop, SE Dobbins, SM Farrington, AM Jones, C Palles, N Whiffin, ... Nature genetics 44 (7), 770-776, 2012 | 279 | 2012 |
| Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis D Rosmarin, C Palles, D Church, E Domingo, A Jones, E Johnstone, ... Journal of Clinical Oncology 32 (10), 1031, 2014 | 260 | 2014 |
| KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer J Tie, L Lipton, J Desai, P Gibbs, RN Jorissen, M Christie, KJ Drummond, ... Clinical Cancer Research 17 (5), 1122-1130, 2011 | 260 | 2011 |
| Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status C Oliveira, JL Westra, D Arango, M Ollikainen, E Domingo, A Ferreira, ... Human molecular genetics 13 (19), 2303-2311, 2004 | 239 | 2004 |
| Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer E Domingo, DN Church, O Sieber, R Ramamoorthy, Y Yanagisawa, ... Journal of clinical oncology 31 (34), 4297-4305, 2013 | 238 | 2013 |
| BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes E Domingo, RC Niessen, C Oliveira, P Alhopuro, C Moutinho, E Espín, ... Oncogene 24 (24), 3995-3998, 2005 | 218 | 2005 |
| Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning K Sirinukunwattana, E Domingo, SD Richman, KL Redmond, A Blake, ... Gut 70 (3), 544-554, 2021 | 175 | 2021 |
