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Emmanuel Planel
Emmanuel Planel
Université Laval, CR-CHU de Québec
Verified email at planel.org
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Year
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
W Noble, E Planel, C Zehr, V Olm, J Meyerson, F Suleman, K Gaynor, ...
Proceedings of the national academy of sciences 102 (19), 6990-6995, 2005
9122005
Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia
E Planel, KEG Richter, CE Nolan, JE Finley, L Liu, Y Wen, ...
Journal of Neuroscience 27 (12), 3090-3097, 2007
4492007
Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration
SS Hébert, AS Papadopoulou, P Smith, MC Galas, E Planel, ...
Human molecular genetics 19 (20), 3959-3969, 2010
3512010
Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for …
E Planel, T Miyasaka, T Launey, DH Chui, K Tanemura, S Sato, ...
Journal of Neuroscience 24 (10), 2401-2411, 2004
3302004
Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau
Y Tatebayashi, T Miyasaka, DH Chui, T Akagi, K Mishima, K Iwasaki, ...
Proceedings of the National Academy of Sciences 99 (21), 13896-13901, 2002
3212002
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar
V Jevtovic-Todorovic, AR Absalom, K Blomgren, A Brambrink, G Crosby, ...
British journal of anaesthesia 111 (2), 143-151, 2013
2972013
Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms
E Planel, Y Tatebayashi, T Miyasaka, L Liu, L Wang, M Herman, WH Yu, ...
Journal of Neuroscience 27 (50), 13635-13648, 2007
2972007
Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Aβ accumulation
A Muhammad, I Flores, H Zhang, R Yu, A Staniszewski, E Planel, ...
Proceedings of the National Academy of Sciences 105 (20), 7327-7332, 2008
2772008
A neuronal microtubule-interacting agent, NAPVSIPQ, reduces tau pathology and enhances cognitive function in a mouse model of Alzheimer's disease
Y Matsuoka, Y Jouroukhin, AJ Gray, L Ma, C Hirata-Fukae, HF Li, L Feng, ...
Journal of Pharmacology and Experimental Therapeutics 325 (1), 146-153, 2008
2632008
Inhibition of protein phosphatase 2A overrides tau protein kinase I/glycogen synthase kinase 3β and cyclin-dependent kinase 5 inhibition and results in tau hyperphosphorylation …
E Planel, K Yasutake, SC Fujita, K Ishiguro
Journal of Biological Chemistry 276 (36), 34298-34306, 2001
2522001
Insulin reverses the high-fat diet–induced increase in brain Aβ and improves memory in an animal model of Alzheimer disease
M Vandal, PJ White, C Tremblay, I St-Amour, G Chevrier, V Emond, ...
Diabetes 63 (12), 4291-4301, 2014
2342014
Transcriptional regulation of β-secretase by p25/cdk5 leads to enhanced amyloidogenic processing
Y Wen, WH Yu, B Maloney, J Bailey, J Ma, I Marié, T Maurin, L Wang, ...
Neuron 57 (5), 680-690, 2008
2242008
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo
PY Smith, J Hernandez-Rapp, F Jolivette, C Lecours, K Bisht, C Goupil, ...
Human molecular genetics 24 (23), 6721-6735, 2015
2212015
Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric α-synuclein
WH Yu, B Dorado, HY Figueroa, L Wang, E Planel, MR Cookson, ...
The American journal of pathology 175 (2), 736-747, 2009
1862009
MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy
PY Smith, C Delay, J Girard, MA Papon, E Planel, N Sergeant, L Buée, ...
Human molecular genetics 20 (20), 4016-4024, 2011
1752011
Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD)
M Filali, R Lalonde, P Theriault, C Julien, F Calon, E Planel
Behavioural brain research 234 (2), 334-342, 2012
1732012
Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3β mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid …
Y Wen, E Planel, M Herman, HY Figueroa, L Wang, L Liu, LF Lau, WH Yu, ...
Journal of Neuroscience 28 (10), 2624-2632, 2008
1712008
Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia
E Planel, A Bretteville, L Liu, L Virag, AL Du, WH Yu, DW Dickson, ...
The FASEB Journal 23 (8), 2595, 2009
1632009
Propofol directly increases tau phosphorylation
RA Whittington, L Virág, F Marcouiller, MA Papon, NBE Khoury, C Julien, ...
PloS one 6 (1), e16648, 2011
1502011
Aberrant tau phosphorylation by glycogen synthase kinase-3β and JNK3 induces oligomeric tau fibrils in COS-7 cells
S Sato, Y Tatebayashi, T Akagi, DH Chui, M Murayama, T Miyasaka, ...
Journal of Biological Chemistry 277 (44), 42060-42065, 2002
1492002
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