| “Perfect” designer chromosome V and behavior of a ring derivative ZX Xie, BZ Li, LA Mitchell, Y Wu, X Qi, Z Jin, B Jia, X Wang, BX Zeng, ... Science 355 (6329), eaaf4704, 2017 | 287 | 2017 |
| Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome Y Shen, Y Wang, T Chen, F Gao, J Gong, D Abramczyk, R Walker, H Zhao, ... Science 355 (6329), eaaf4791, 2017 | 239 | 2017 |
| Engineering the ribosomal DNA in a megabase synthetic chromosome W Zhang, G Zhao, Z Luo, Y Lin, L Wang, Y Guo, A Wang, S Jiang, Q Jiang, ... Science 355 (6329), eaaf3981, 2017 | 236 | 2017 |
| Oil accumulation mechanisms of the oleaginous microalga Chlorella protothecoides revealed through its genome, transcriptomes, and proteomes C Gao, Y Wang, Y Shen, D Yan, X He, J Dai, Q Wu BMC genomics 15, 1-14, 2014 | 202 | 2014 |
| SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes Y Shen, G Stracquadanio, Y Wang, K Yang, LA Mitchell, Y Xue, Y Cai, ... Genome research 26 (1), 36-49, 2016 | 158 | 2016 |
| 3D organization of synthetic and scrambled chromosomes G Mercy, J Mozziconacci, VF Scolari, K Yang, G Zhao, A Thierry, Y Luo, ... Science 355 (6329), eaaf4597, 2017 | 151 | 2017 |
| Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods W Liu, Z Luo, Y Wang, NT Pham, L Tuck, I Pérez-Pi, L Liu, Y Shen, ... Nature communications 9 (1), 1936, 2018 | 147 | 2018 |
| YeastFab: the design and construction of standard biological parts for metabolic engineering in Saccharomyces cerevisiae Y Guo, J Dong, T Zhou, J Auxillos, T Li, W Zhang, L Wang, Y Shen, Y Luo, ... Nucleic acids research 43 (13), e88-e88, 2015 | 130 | 2015 |
| Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES Z Luo, L Wang, Y Wang, W Zhang, Y Guo, Y Shen, L Jiang, Q Wu, ... Nature communications 9 (1), 1930, 2018 | 129 | 2018 |
| Towards practical and robust DNA-based data archiving using the yin–yang codec system Z Ping, S Chen, G Zhou, X Huang, SJ Zhu, H Zhang, HH Lee, Z Lan, J Cui, ... Nature Computational Science 2 (4), 234-242, 2022 | 64* | 2022 |
| Carbon-based archiving: current progress and future prospects of DNA-based data storage Z Ping, D Ma, X Huang, S Chen, L Liu, F Guo, SJ Zhu, Y Shen GigaScience 8 (6), giz075, 2019 | 63 | 2019 |
| Smart DNA fabrication using sound waves: applying acoustic dispensing technologies to synthetic biology P Kanigowska, Y Shen, Y Zheng, S Rosser, Y Cai Journal of laboratory automation 21 (1), 49-56, 2016 | 60 | 2016 |
| Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions Y Zhao, C Coelho, AL Hughes, L Lazar-Stefanita, S Yang, AN Brooks, ... Cell 186 (24), 5220-5236. e16, 2023 | 47 | 2023 |
| Sequencing and comparative analysis of three Chlorella genomes provide insights into strain-specific adaptation to wastewater T Wu, L Li, X Jiang, Y Yang, Y Song, L Chen, X Xu, Y Shen, Y Gu Scientific reports 9 (1), 9514, 2019 | 39 | 2019 |
| Design and chemical synthesis of eukaryotic chromosomes ZX Xie, D Liu, BZ Li, M Zhao, BX Zeng, Y Wu, Y Shen, T Lin, P Yang, J Dai, ... Chemical Society Reviews 46 (23), 7191-7207, 2017 | 34 | 2017 |
| Design, construction, and functional characterization of a tRNA neochromosome in yeast D Schindler, RSK Walker, S Jiang, AN Brooks, Y Wang, CA Müller, ... Cell 186 (24), 5237-5253. e22, 2023 | 32 | 2023 |
| Frequent gene conversion in human embryos induced by double strand breaks D Liang, NM Gutierrez, T Chen, Y Lee, SW Park, H Ma, A Koski, R Ahmed, ... bioRxiv, 2020.06. 19.162214, 2020 | 32 | 2020 |
| Auxenochlorella protothecoides and Prototheca wickerhamii plastid genome sequences give insight into the origins of non-photosynthetic algae D Yan, Y Wang, T Murakami, Y Shen, J Gong, H Jiang, DR Smith, ... Scientific Reports 5 (1), 14465, 2015 | 27 | 2015 |
| Dissecting aneuploidy phenotypes by constructing Sc2. 0 chromosome VII and SCRaMbLEing synthetic disomic yeast Y Shen, F Gao, Y Wang, Y Wang, J Zheng, J Gong, J Zhang, Z Luo, ... Cell genomics 3 (11), 2023 | 19 | 2023 |
| Systematic dissection of key factors governing recombination outcomes by GCE-SCRaMbLE H Zhang, X Fu, X Gong, Y Wang, H Zhang, Y Zhao, Y Shen Nature Communications 13 (1), 5836, 2022 | 17 | 2022 |
