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| A sting in the tail: the N-terminal domain of the androgen receptor as a drug target AE Monaghan, IJ McEwan Asian Journal of Andrology 18 (5), 687-694, 2016 | 48 | 2016 |
| 5-Hydroxytryptamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database R Andrade, NM Barnes, G Baxter, J Bockaert, T Branchek, A Butler, ... IUPHAR/BPS Guide to Pharmacology CITE 2019 (4), 2019 | 31* | 2019 |
| Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen BN Atkinson, D Steadman, Y Zhao, J Sipthorp, L Vecchia, RR Ruza, ... MedChemComm 10 (8), 1361-1369, 2019 | 28 | 2019 |
| Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11. 2 and MAPT H1 loci MPM Soutar, D Melandri, B O’Callaghan, E Annuario, AE Monaghan, ... Brain 145 (12), 4349-4367, 2022 | 27 | 2022 |
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| Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila ML Atilano, S Grönke, T Niccoli, L Kempthorne, O Hahn, J Moron-Oset, ... Elife 10, e58565, 2021 | 17 | 2021 |
| 5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment … W Mahy, NJ Willis, Y Zhao, HL Woodward, F Svensson, J Sipthorp, ... Journal of medicinal chemistry 63 (21), 12942-12956, 2020 | 16 | 2020 |
| Scaffold-hopping identifies furano [2, 3-d] pyrimidine amides as potent Notum inhibitors BN Atkinson, D Steadman, W Mahy, Y Zhao, J Sipthorp, ED Bayle, ... Bioorganic & Medicinal Chemistry Letters 30 (3), 126751, 2020 | 15 | 2020 |
| Screening of a custom-designed acid fragment library identifies 1-phenylpyrroles and 1-phenylpyrrolidines as inhibitors of Notum carboxylesterase activity W Mahy, M Patel, D Steadman, HL Woodward, BN Atkinson, F Svensson, ... Journal of medicinal chemistry 63 (17), 9464-9483, 2020 | 13 | 2020 |
| Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at Chr16q11. 2 and on the MAPT H1 allele MPM Soutar, D Melandri, B O’Callaghan, E Annuario, AE Monaghan, ... BioRxiv, 2020.01. 06.896241, 2020 | 11 | 2020 |
| Virtual screening directly identifies new fragment-sized inhibitors of carboxylesterase Notum with nanomolar activity D Steadman, BN Atkinson, Y Zhao, NJ Willis, S Frew, A Monaghan, ... Journal of Medicinal Chemistry 65 (1), 562-578, 2021 | 10 | 2021 |
| Design of a Potent, selective, and brain-penetrant inhibitor of Wnt-deactivating enzyme notum by optimization of a crystallographic fragment hit NJ Willis, W Mahy, J Sipthorp, Y Zhao, HL Woodward, BN Atkinson, ... Journal of medicinal chemistry 65 (10), 7212-7230, 2022 | 9 | 2022 |
| Structural insights into notum covalent inhibition Y Zhao, F Svensson, D Steadman, S Frew, A Monaghan, M Bictash, ... Journal of Medicinal Chemistry 64 (15), 11354-11363, 2021 | 8 | 2021 |
| Development of a High-Throughput Screening Assay for Small-Molecule Inhibitors of Androgen Receptor Splice Variants AE Monaghan, A Porter, I Hunter, A Morrison, SP McElroy, IJ McEwan ASSAY and Drug Development Technologies 20 (3), 111-124, 2022 | 4 | 2022 |
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| Class A orphans in GtoPdb v. 2021.3 SPH Alexander, J Battey, HE Benson, RV Benya, TI Bonner, ... IUPHAR/BPS Guide to Pharmacology CITE 2021 (3), 2021 | 2 | 2021 |
| Class A orphans in GtoPdb v. 2023.1 SPH Alexander, J Battey, HE Benson, RV Benya, TI Bonner, ... IUPHAR/BPS Guide to Pharmacology CITE 2023 (1), 2023 | 1 | 2023 |
