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Andreas Brust
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Differential evolution and neofunctionalization of snake venom metalloprotease domains
A Brust, K Sunagar, EAB Undheim, I Vetter, DC Yang, NR Casewell, ...
Molecular & Cellular Proteomics 12 (3), 651-663, 2013
1082013
χ-Conopeptide pharmacophore development: Toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain
A Brust, E Palant, DE Croker, B Colless, R Drinkwater, B Patterson, ...
Journal of medicinal chemistry 52 (22), 6991-7002, 2009
942009
Cone snail venomics: from novel biology to novel therapeutics
JR Prashanth, A Brust, AH Jin, PF Alewood, S Dutertre, RJ Lewis
Future medicinal chemistry 6 (15), 1659-1675, 2014
912014
High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain
LJ Drew, F Rugiero, P Cesare, JE Gale, B Abrahamsen, S Bowden, ...
PloS one 2 (6), e515, 2007
832007
Libraries of peptide conjugates and methods for making them
AF Brust
US Patent App. 13/061,744, 2011
802011
Sugar-derived building blocks. Part 26. Part 25. See ref. 1. Hydrophilic pyrroles, pyridazines and diazepinones from d-fructose and isomaltulose
FW Lichtenthaler, A Brust, E Cuny
Green Chemistry 3 (5), 201-209, 2001
732001
The snake with the scorpion’s sting: Novel three-finger toxin sodium channel activators from the venom of the long-glanded blue coral snake (Calliophis bivirgatus)
DC Yang, JR Deuis, D Dashevsky, J Dobson, TNW Jackson, A Brust, ...
Toxins 8 (10), 303, 2016
662016
Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors
MC Inserra, SN Kompella, I Vetter, A Brust, NL Daly, H Cuny, DJ Craik, ...
Biochemical pharmacology 86 (6), 791-799, 2013
632013
Phosphorylation and metabolism of sucrose and its five linkage-isomeric α-D-glucosyl-D-fructoses by Klebsiella pneumoniae
J Thompson, SA Robrish, A Pikis, A Brust, FW Lichtenthaler
Carbohydrate Research 331 (2), 149-161, 2001
622001
Understanding the molecular basis of toxin promiscuity: The analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping …
JE Jensen, B Cristofori-Armstrong, R Anangi, KJ Rosengren, CHY Lau, ...
Journal of medicinal chemistry 57 (21), 9195-9203, 2014
532014
Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors
AA Grishin, H Cuny, A Hung, RJ Clark, A Brust, K Akondi, PF Alewood, ...
Journal of Biological Chemistry 288 (48), 34428-34442, 2013
502013
Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation
MP Ikonomopoulou, MA Fernandez-Rojo, SS Pineda, P Cabezas-Sainz, ...
Scientific reports 8 (1), 11519, 2018
472018
Stabilization of the Cysteine‐Rich Conotoxin MrIA by Using a 1, 2, 3‐Triazole as a Disulfide Bond Mimetic
A Gori, CIA Wang, PJ Harvey, KJ Rosengren, RF Bhola, ML Gelmi, ...
Angewandte Chemie International Edition 54 (4), 1361-1364, 2015
462015
Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3
JE Jensen, M Mobli, A Brust, PF Alewood, GF King, LD Rash
Marine Drugs 10 (7), 1511-1527, 2012
342012
Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor
N Abraham, M Healy, L Ragnarsson, A Brust, PF Alewood, RJ Lewis
Scientific reports 7 (1), 45466, 2017
332017
Conopeptide-derived κ-opioid agonists (Conorphins): potent, selective, and metabolic stable dynorphin A mimetics with antinociceptive properties
A Brust, DE Croker, B Colless, L Ragnarsson, Å Andersson, K Jain, ...
Journal of medicinal chemistry 59 (6), 2381-2395, 2016
322016
Conopeptide ρ-TIA Defines a New Allosteric Site on the Extracellular Surface of the α1B-Adrenoceptor*♦
L Ragnarsson, CIA Wang, Å Andersson, D Fajarningsih, T Monks, A Brust, ...
Journal of biological chemistry 288 (3), 1814-1827, 2013
322013
Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter
A Brust, CIA Wang, NL Daly, J Kennerly, M Sadeghi, MJ Christie, ...
Wiley, 2013
292013
High‐throughput synthesis of conopeptides: a safety‐catch linker approach enabling disulfide formation in 96‐well format
A Brust, AE Tickle
Journal of Peptide Science: An Official Publication of the European Peptide …, 2007
292007
Novel analgesic ω-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides
SR Sousa, JR McArthur, A Brust, RF Bhola, KJ Rosengren, L Ragnarsson, ...
Scientific reports 8 (1), 13397, 2018
262018
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