Progesterone induces adult mammary stem cell expansion PA Joshi, HW Jackson, AG Beristain, MA Di Grappa, PA Mote, CL Clarke, ... Nature 465 (7299), 803-807, 2010 | 787 | 2010 |
The single-cell pathology landscape of breast cancer HW Jackson, JR Fischer, VRT Zanotelli, HR Ali, R Mechera, SD Soysal, ... Nature 578 (7796), 615-620, 2020 | 736 | 2020 |
histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data D Schapiro, HW Jackson, S Raghuraman, JR Fischer, VRT Zanotelli, ... Nature methods 14 (9), 873-876, 2017 | 573 | 2017 |
TIMPs: versatile extracellular regulators in cancer HW Jackson, V Defamie, P Waterhouse, R Khokha Nature Reviews Cancer 17 (1), 38-53, 2017 | 442 | 2017 |
Simultaneous multiplexed imaging of mRNA and proteins with subcellular resolution in breast cancer tissue samples by mass cytometry D Schulz, VRT Zanotelli, JR Fischer, D Schapiro, S Engler, XK Lun, ... Cell systems 6 (1), 25-36. e5, 2018 | 281 | 2018 |
Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer HR Ali, HW Jackson, VRT Zanotelli, E Danenberg, JR Fischer, H Bardwell, ... Nature Cancer 1 (2), 163-175, 2020 | 266 | 2020 |
Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state M Shimoda, S Principe, HW Jackson, V Luga, H Fang, SD Molyneux, ... Nature cell biology 16 (9), 889-901, 2014 | 222 | 2014 |
RANK signaling amplifies WNT-responsive mammary progenitors through R-SPONDIN1 PA Joshi, PD Waterhouse, N Kannan, S Narala, H Fang, MA Di Grappa, ... Stem cell reports 5 (1), 31-44, 2015 | 83 | 2015 |
Automated assignment of cell identity from single-cell multiplexed imaging and proteomic data MJ Geuenich, J Hou, S Lee, S Ayub, HW Jackson, KR Campbell Cell Systems 12 (12), 1173-1186. e5, 2021 | 51 | 2021 |
A progesterone-CXCR4 axis controls mammary progenitor cell fate in the adult gland YJ Shiah, P Tharmapalan, AE Casey, PA Joshi, TD McKee, HW Jackson, ... Stem Cell Reports 4 (3), 313-322, 2015 | 49 | 2015 |
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis L Li, KKN Guturi, B Gautreau, PS Patel, A Saad, M Morii, F Mateo, ... The Journal of clinical investigation 128 (10), 4525-4542, 2018 | 40 | 2018 |
Timp3 deficient mice show resistance to developing breast cancer HW Jackson, CV Hojilla, A Weiss, OH Sanchez, GA Wood, R Khokha PLoS One 10 (3), e0120107, 2015 | 36 | 2015 |
Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice HW Jackson, P Waterhouse, A Sinha, T Kislinger, HK Berman, R Khokha Nature cell biology 17 (3), 217-227, 2015 | 31 | 2015 |
TIMP3 regulates mammary epithelial apoptosis with immune cell recruitment through differential TNF dependence CV Hojilla, HW Jackson, R Khokha PloS one 6 (10), e26718, 2011 | 30 | 2011 |
Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis, and promotes breast cancer E Langille, KN Al-Zahrani, Z Ma, M Liang, L Uuskula-Reimand, R Espin, ... Cancer discovery 12 (12), 2930-2953, 2022 | 26 | 2022 |
Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer LDV Roditi, A Jacobs, JH Rueschoff, P Bankhead, S Chevrier, ... Cell reports medicine 3 (4), 2022 | 26 | 2022 |
In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer D Dervovic, AA Malik, ELY Chen, M Narimatsu, N Adler, S Afiuni-Zadeh, ... Nature communications 14 (1), 3150, 2023 | 22 | 2023 |
Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer P Kündig, C Giesen, H Jackson, B Bodenmiller, B Papassotirolopus, ... Journal of translational medicine 16, 1-16, 2018 | 21 | 2018 |
Multiplex imaging of breast cancer lymph node metastases identifies prognostic single-cell populations independent of clinical classifiers JR Fischer, HW Jackson, N de Souza, Z Varga, P Schraml, H Moch, ... Cell Reports Medicine 4 (3), 2023 | 16 | 2023 |
Tumor suppression by stromal TIMPs M Shimoda, HW Jackson, R Khokha Molecular & cellular oncology 3 (3), e975082, 2016 | 15 | 2016 |