| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13133* | 2021 |
| TSC2 mediates cellular energy response to control cell growth and survival K Inoki, T Zhu, KL Guan Cell 115 (5), 577-590, 2003 | 4665 | 2003 |
| TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling K Inoki, Y Li, T Zhu, J Wu, KL Guan Nature cell biology 4 (9), 648-657, 2002 | 3782 | 2002 |
| Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling K Inoki, Y Li, T Xu, KL Guan Genes & development 17 (15), 1829-1834, 2003 | 2289 | 2003 |
| TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth K Inoki, H Ouyang, T Zhu, C Lindvall, Y Wang, X Zhang, Q Yang, ... Cell 126 (5), 955-968, 2006 | 1584 | 2006 |
| Dysregulation of the TSC-mTOR pathway in human disease K Inoki, MN Corradetti, KL Guan Nature genetics 37 (1), 19-24, 2005 | 1191 | 2005 |
| AMPK and mTOR in cellular energy homeostasis and drug targets K Inoki, J Kim, KL Guan Annual review of pharmacology and toxicology 52, 381-400, 2012 | 839 | 2012 |
| ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS A Alexander, SL Cai, J Kim, A Nanez, M Sahin, KH MacLean, K Inoki, ... Proceedings of the National Academy of Sciences 107 (9), 4153-4158, 2010 | 792 | 2010 |
| Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling T Ikenoue, K Inoki, Q Yang, X Zhou, KL Guan The EMBO journal 27 (14), 1919-1931, 2008 | 755 | 2008 |
| Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome MN Corradetti, K Inoki, N Bardeesy, RA DePinho, KL Guan Genes & development 18 (13), 1533-1538, 2004 | 691 | 2004 |
| Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity Q Yang, K Inoki, T Ikenoue, KL Guan Genes & development 20 (20), 2820-2832, 2006 | 627 | 2006 |
| mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice K Inoki, H Mori, J Wang, T Suzuki, SK Hong, S Yoshida, SM Blattner, ... The Journal of clinical investigation 121 (6), 2181-2196, 2011 | 588 | 2011 |
| Role of mTOR in podocyte function and diabetic nephropathy in humans and mice M Gödel, B Hartleben, N Herbach, S Liu, S Zschiedrich, S Lu, ... The Journal of clinical investigation 121 (6), 2197-2209, 2011 | 577 | 2011 |
| Spatial coupling of mTOR and autophagy augments secretory phenotypes M Narita, ARJ Young, S Arakawa, SA Samarajiwa, T Nakashima, ... Science 332 (6032), 966-970, 2011 | 569 | 2011 |
| TSC2: filling the GAP in the mTOR signaling pathway Y Li, MN Corradetti, K Inoki, KL Guan Trends in biochemical sciences 29 (1), 32-38, 2004 | 512 | 2004 |
| Signaling by target of rapamycin proteins in cell growth control K Inoki, H Ouyang, Y Li, KL Guan Microbiology and Molecular Biology Reviews 69 (1), 79-100, 2005 | 455 | 2005 |
| The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway MN Corradetti, K Inoki, KL Guan Journal of Biological Chemistry 280 (11), 9769-9772, 2005 | 308 | 2005 |
| TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase H Chong-Kopera, K Inoki, Y Li, T Zhu, FR Garcia-Gonzalo, JL Rosa, ... Journal of Biological Chemistry 281 (13), 8313-8316, 2006 | 299 | 2006 |
| Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity Y Li, K Inoki, KL Guan Molecular and cellular biology 24 (18), 7965-7975, 2004 | 292 | 2004 |
| A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression CL Buller, RD Loberg, MH Fan, Q Zhu, JL Park, E Vesely, K Inoki, ... American Journal of Physiology-Cell Physiology 295 (3), C836-C843, 2008 | 280 | 2008 |
