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Manuela Gellert
Manuela Gellert
Postdoctoral Fellow, University Greifswald
Verified email at uni-greifswald.de
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Molecular architecture of Streptococcus pneumoniae surface thioredoxin‐fold lipoproteins crucial for extracellular oxidative stress resistance and maintenance of …
M Saleh, SG Bartual, MR Abdullah, I Jensch, TM Asmat, L Petruschka, ...
EMBO molecular medicine 5 (12), 1852-1870, 2013
118*2013
Vertebrate-specific glutaredoxin is essential for brain development
L Bräutigam, LD Schütte, JR Godoy, T Prozorovski, M Gellert, ...
Proceedings of the National Academy of Sciences 108 (51), 20532-20537, 2011
1022011
Molecular basis for the distinct functions of redox-active and FeS-transfering glutaredoxins
D Trnka, AD Engelke, M Gellert, A Moseler, MF Hossain, TT Lindenberg, ...
Nature communications 11 (1), 3445, 2020
512020
Redox regulation of cytoskeletal dynamics during differentiation and de-differentiation
M Gellert, EM Hanschmann, K Lepka, C Berndt, CH Lillig
Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (8), 1575-1587, 2015
452015
Identification of a dithiol-disulfide switch in collapsin response mediator protein 2 (CRMP2) that is toggled in a model of neuronal differentiation
M Gellert, S Venz, J Mitlöhner, C Cott, EM Hanschmann, CH Lillig
Journal of Biological Chemistry 288 (49), 35117-35125, 2013
442013
Substrate specificity of thioredoxins and glutaredoxins–towards a functional classification
M Gellert, MF Hossain, FJF Berens, LW Bruhn, C Urbainsky, V Liebscher, ...
Heliyon 5 (12), 2019
412019
Thioredoxin 1 and glutaredoxin 2 contribute to maintain the phenotype and integrity of neurons following perinatal asphyxia
JI Romero, EM Hanschmann, M Gellert, S Eitner, MI Holubiec, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (6), 1274-1285, 2015
322015
Role of GSH and iron-sulfur glutaredoxins in iron metabolism
T Daniel, HM Faruq, J Laura Magdalena, G Manuela, L Christopher Horst
Molecules 25 (17), 3860, 2020
302020
Redox signaling and metabolism in Alzheimer's disease
MI Holubiec, M Gellert, EM Hanschmann
Frontiers in Aging Neuroscience 14, 1003721, 2022
222022
Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death
L Hoffmann, MS Waclawczyk, S Tang, EM Hanschmann, M Gellert, ...
Cell Death & Disease 12 (11), 953, 2021
182021
Signal-regulated oxidation of proteins via MICAL
C Ortegón Salas, K Schneider, CH Lillig, M Gellert
Biochemical Society Transactions 48 (2), 613-620, 2020
162020
Molecular dynamics simulations and in vitro analysis of the CRMP2 thiol switch
D Möller, M Gellert, W Langel, CH Lillig
Molecular BioSystems 13 (9), 1744-1753, 2017
132017
The cytosolic isoform of glutaredoxin 2 promotes cell migration and invasion
M Gellert, E Richter, J Mostertz, L Kantz, K Masur, EM Hanschmann, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (7), 129599, 2020
122020
Thioredoxin 1 (Trx1) is associated with poor prognosis in clear cell renal cell carcinoma (ccRCC): an example for the crucial role of redox signaling in ccRCC
S Ribback, S Winter, T Klatte, E Schaeffeler, M Gellert, V Stühler, ...
World Journal of Urology, 1-8, 2022
62022
p53 is functionally inhibited in clear cell renal cell carcinoma (ccRCC): A mechanistic and correlative investigation into genetic and molecular characteristics
K Diesing, S Ribback, S Winter, M Gellert, AM Oster, V Stühler, E Gläser, ...
Journal of Cancer Research and Clinical Oncology 147, 3565-3576, 2021
62021
Molecular basis for the interactions of human thioredoxins with their respective reductases
MF Hossain, Y Bodnar, C Klein, CO Salas, ESJ Arnér, M Gellert, CH Lillig
Oxidative Medicine and Cellular Longevity 2021, 1-17, 2021
62021
Functional metagenomics of the thioredoxin superfamily
S Nilewski, M Varatnitskaya, T Masuch, A Kusnezowa, M Gellert, ...
Journal of Biological Chemistry 296, 2021
52021
FeS-cluster coordination of vertebrate thioredoxin regulates suppression of hypoxia-induced factor 2α through iron regulatory protein 1
C Berndt, EM Hanschmann, LM Jordt, M Gellert, L Thewes, CO Salas, ...
BioRxiv, 2020.08. 04.235721, 2020
42020
Localization of four class I glutaredoxins in the cytosol and the secretory pathway and characterization of their biochemical diversification
M Schlößer, A Moseler, Y Bodnar, M Homagk, S Wagner, L Pedroletti, ...
The Plant Journal, 2023
32023
Breakdown of Arabidopsis thaliana thioredoxins and glutaredoxins based on electrostatic similarity–Leads to common and unique interaction partners and functions
Y Bodnar, M Gellert, FM Hossain, CH Lillig
PLoS One 18 (9), e0291272, 2023
12023
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