James Fraser
James Fraser
Department of Biochemistry, McGill University
Adresse e-mail validée de mail.mcgill.ca
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Complexity of chromatin folding is captured by the strings and binders switch model
M Barbieri, M Chotalia, J Fraser, LM Lavitas, J Dostie, A Pombo, ...
Proceedings of the National Academy of Sciences, 2012
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
HF Zheng, V Forgetta, YH Hsu, K Estrada, A Rosello‐Diez, PJ Leo, ...
Nature 526 (7571), 112-117, 2015
Complex multi-enhancer contacts captured by genome architecture mapping
RA Beagrie, A Scialdone, M Schueler, DCA Kraemer, M Chotalia, SQ Xie, ...
Nature 543 (7646), 519-524, 2017
Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation
J Fraser, C Ferrai, AM Chiariello, M Schueler, T Rito, G Laudanno, ...
Molecular systems biology 11 (12), 2015
Three-dimensional modeling of chromatin structure from interaction frequency data using Markov chain Monte Carlo sampling
M Rousseau, J Fraser, MA Ferraiuolo, J Dostie, M Blanchette
BMC bioinformatics 12 (1), 414, 2011
An overview of genome organization and how we got there: from FISH to Hi-C
J Fraser, I Williamson, WA Bickmore, J Dostie
Microbiol. Mol. Biol. Rev. 79 (3), 347-372, 2015
Chromatin conformation signatures of cellular differentiation
J Fraser, M Rousseau, S Shenker, MA Ferraiuolo, Y Hayashizaki, ...
Genome biology 10 (4), R37, 2009
Repurposing CRISPR/Cas9 for in situ functional assays
A Malina, JR Mills, R Cencic, Y Yan, J Fraser, LM Schippers, M Paquet, ...
Genes & development 27 (23), 2602-2614, 2013
Heat-Induced Dimerization of BCL-xL through α-Helix Swapping
AY Denisov, T Sprules, J Fraser, G Kozlov, K Gehring
Biochemistry 46 (3), 734-740, 2007
A polymer model explains the complexity of large-scale chromatin folding
M Barbieri, J Fraser, LM Lavitas, M Chotalia, J Dostie, A Pombo, ...
Nucleus 4 (4), 267-273, 2013
Computing chromosome conformation
J Fraser, M Rousseau, M Blanchette, J Dostie
Computational Biology of Transcription Factor Binding, 251-268, 2010
A Torrent of Data: Mapping Chromatin Organization Using 5C and High-Throughput Sequencing
J Fraser, SD Ethier, H Miura, J Dostie
Nucleosomes, Histones & Chromatin, 113, 2012
A model of the large-scale organization of chromatin
B Mariano, C Mita, F James, L Liron-Mark, D Josee, P Ana, N Mario
Biochemical Society Transactions 41 (2), 508-512, 2013
Complex multi-enhancer contacts captured by genome architecture mapping, a novel ligation-free approach
A Pombo, RA Beagrie, A Scialdone, M Schueler, M Chotalia, SQ Xie, ...
The FASEB Journal 30 (1_supplement), 99.3-99.3, 2016
Mapping and Visualizing Spatial Genome Organization
CJF Cameron, J Fraser, M Blanchette, J Dostie
The Functional Nucleus, 359-383, 2016
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