Greg Towers

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Mahdad NoursadeghiUniversity College LondonVerified email at ucl.ac.uk
Adam J. FletcherMRC University of Glasgow Centre for Virus ResearchVerified email at glasgow.ac.uk
David JacquesSchool of Biomedical Sciences, University of New South Wales, AustraliaVerified email at unsw.edu.au
Ravindra Kumar GuptaUniversity of CambridgeVerified email at cam.ac.uk
Paul BieniaszProfessor, The Rockefeller universityVerified email at rockefeller.edu
William A McEwanUK Dementia Research Institute, University of CambridgeVerified email at cam.ac.uk
Paul KellamImperial College London & RQ Biotechnology LtdVerified email at imperial.ac.uk
Stephen P. GoffProfessor of Biochemistry and Molecular Biophysics, Columbia UniversityVerified email at cumc.columbia.edu
Vineet KewalRamaniNational Institutes of Health, USAVerified email at mail.nih.gov
Troy BradyUniversity of Pennsylvania, Iowa State UniversityVerified email at auburn.edu
Jeremy LubanUMass Med, Broad Institute of MIT and Harvard, Ragon Institute of MGH, MIT, & Harvard; MassCPRVerified email at umassmed.edu
Aris KatzourakisProfessor of Evolution and Genomics, University of OxfordVerified email at biology.ox.ac.uk
Jeremy GarsonUCLVerified email at ucl.ac.uk
Robert J. GiffordUniversity of GlasgowVerified email at glasgow.ac.uk
Jonathan Luke HeeneyProfessor of Comparative Pathology, University of CambridgeVerified email at cam.ac.uk
Yasuhiro ikedaExecutive Director, Cell Therapeutics and Viral Technologies, R&D, AstraZenecaVerified email at astrazeneca.com
Benny ChainUCLVerified email at ucl.ac.uk
Richard JennerProfessor of Molecular Biology, University College LondonVerified email at ucl.ac.uk
Julia G PradoIrsicaixaVerified email at irsicaixa.es
jason chin OR jason w. chin OR chin JWVerified email at mrc-lmb.cam.ac.uk

Greg Towers

university college london

Verified email at ucl.ac.uk

virology


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SARS-CoV-2 variant biology: immune escape, transmission and fitness AM Carabelli, TP Peacock, LG Thorne, WT Harvey, J Hughes, SJ Peacock, ... Nature Reviews Microbiology 21 (3), 162-177, 2023	1037	2023
Positional cloning of the mouse retrovirus restriction gene Fvl S Best, PL Tissier, G Towers, JP Stoye Nature 382 (6594), 826-829, 1996	609	1996
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency T Schaller, KE Ocwieja, J Rasaiyaah, AJ Price, TL Brady, SL Roth, S Hué, ... PLoS pathogens 7 (12), e1002439, 2011	573	2011
Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21) DL Mallery, WA McEwan, SR Bidgood, GJ Towers, CM Johnson, ... Proceedings of the National Academy of Sciences 107 (46), 19985-19990, 2010	570	2010
HIV-1 evades innate immune recognition through specific cofactor recruitment J Rasaiyaah, CP Tan, AJ Fletcher, AJ Price, C Blondeau, L Hilditch, ... Nature 503 (7476), 402-405, 2013	549	2013
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors GJ Towers, T Hatziioannou, S Cowan, SP Goff, J Luban, PD Bieniasz Nature medicine 9 (9), 1138-1143, 2003	503	2003
The human and African green monkey TRIM5α genes encode Ref1 and Lv1 retroviral restriction factor activities Z Keckesova, LMJ Ylinen, GJ Towers Proceedings of the National Academy of Sciences 101 (29), 10780-10785, 2004	441	2004
Evolution of enhanced innate immune evasion by SARS-CoV-2 LG Thorne, M Bouhaddou, AK Reuschl, L Zuliani-Alvarez, B Polacco, ... Nature 602 (7897), 487-495, 2022	433	2022
Restriction of lentivirus in monkeys C Besnier, Y Takeuchi, G Towers Proceedings of the National Academy of Sciences 99 (18), 11920-11925, 2002	384	2002
A conserved mechanism of retrovirus restriction in mammals G Towers, M Bock, S Martin, Y Takeuchi, JP Stoye, O Danos Proceedings of the National Academy of Sciences 97 (22), 12295-12299, 2000	332	2000
CPSF6 defines a conserved capsid interface that modulates HIV-1 replication AJ Price, AJ Fletcher, T Schaller, T Elliott, KE Lee, VN KewalRamani, ... Public Library of Science 8 (8), e1002896, 2012	314	2012
The control of viral infection by tripartite motif proteins and cyclophilin A GJ Towers Retrovirology 4, 1-10, 2007	311	2007
Restriction of multiple divergent retroviruses by Lv1 and Ref1 T Hatziioannou, S Cowan, SP Goff, PD Bieniasz, GJ Towers The EMBO journal, 2003	306	2003
TRIM22 inhibits influenza A virus infection by targeting the viral nucleoprotein for degradation A Di Pietro, A Kajaste-Rudnitski, A Oteiza, L Nicora, GJ Towers, N Mechti, ... Journal of virology 87 (8), 4523-4533, 2013	273	2013
Independent evolution of an antiviral TRIMCyp in rhesus macaques SJ Wilson, BLJ Webb, LMJ Ylinen, E Verschoor, JL Heeney, GJ Towers Proceedings of the National Academy of Sciences 105 (9), 3557-3562, 2008	271	2008
HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2 KE Ocwieja, TL Brady, K Ronen, A Huegel, SL Roth, T Schaller, ... PLoS pathogens 7 (3), e1001313, 2011	270	2011
HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis DA Jacques, WA McEwan, L Hilditch, AJ Price, GJ Towers, LC James Nature 536 (7616), 349-353, 2016	261	2016
Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion RK Gupta, S Hué, T Schaller, E Verschoor, D Pillay, GJ Towers PLoS pathogens 5 (5), e1000443, 2009	223	2009
SARS‐CoV‐2 sensing by RIG‐I and MDA5 links epithelial infection to macrophage inflammation LG Thorne, AK Reuschl, L Zuliani‐Alvarez, MVX Whelan, J Turner, ... The EMBO journal 40 (15), e107826, 2021	213	2021
Disease-associated XMRV sequences are consistent with laboratory contamination S Hué, ER Gray, A Gall, A Katzourakis, CP Tan, CJ Houldcroft, S McLaren, ... Retrovirology 7, 1-10, 2010	212	2010

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