Brian Marsden
Brian Marsden
Centre for Medicines Discovery & Kennedy Institute of Rheumatology
Verified email at - Homepage
Cited by
Cited by
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
O Abani, A Abbas, F Abbas, M Abbas, S Abbasi, H Abbass, A Abbott, ...
The Lancet 397 (10285), 1637-1645, 2021
Antibody status and incidence of SARS-CoV-2 infection in health care workers
SF Lumley, D O’Donnell, NE Stoesser, PC Matthews, A Howarth, ...
New England Journal of Medicine 384 (6), 533-540, 2021
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature chemical biology 11 (8), 536-541, 2015
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
M Vedadi, FH Niesen, A Allali-Hassani, OY Fedorov, PJ Finerty Jr, ...
Proceedings of the National Academy of Sciences 103 (43), 15835-15840, 2006
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases
O Fedorov, B Marsden, V Pogacic, P Rellos, S Müller, AN Bullock, ...
Proceedings of the National Academy of Sciences 104 (51), 20523-20528, 2007
High-throughput production of human proteins for crystallization: the SGC experience
P Savitsky, J Bray, CDO Cooper, BD Marsden, P Mahajan, ...
Journal of structural biology 172 (1), 3-13, 2010
Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison
M Ainsworth, M Andersson, K Auckland, JK Baillie, E Barnes, S Beer, ...
The Lancet Infectious Diseases 20 (12), 1390-1400, 2020
Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states
CA Shintre, ACW Pike, Q Li, JI Kim, AJ Barr, S Goubin, L Shrestha, J Yang, ...
Proceedings of the National Academy of Sciences 110 (24), 9710-9715, 2013
Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases
P Canning, CDO Cooper, T Krojer, JW Murray, ACW Pike, A Chaikuad, ...
Journal of Biological Chemistry 288 (11), 7803-7814, 2013
Colchicine in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
RC Group
The Lancet Respiratory Medicine 9 (12), 1419-1426, 2021
Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study
DW Eyre, SF Lumley, D O'Donnell, M Campbell, E Sims, E Lawson, ...
elife 9, e60675, 2020
3, 5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands
DS Hewings, M Wang, M Philpott, O Fedorov, S Uttarkar, ...
Journal of medicinal chemistry 54 (19), 6761-6770, 2011
Identification of a chemical probe for bromo and extra C-terminal bromodomain inhibition through optimization of a fragment-derived hit
PV Fish, P Filippakopoulos, G Bish, PE Brennan, ME Bunnage, AS Cook, ...
Journal of medicinal chemistry 55 (22), 9831-9837, 2012
Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase
AN Bullock, JÉ Debreczeni, OY Fedorov, A Nelson, BD Marsden, S Knapp
Journal of medicinal chemistry 48 (24), 7604-7614, 2005
Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom
J Wei, N Stoesser, PC Matthews, D Ayoubkhani, R Studley, I Bell, JI Bell, ...
Nature Microbiology 6 (9), 1140-1149, 2021
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density
NM Pearce, T Krojer, AR Bradley, P Collins, RP Nowak, R Talon, ...
Nature communications 8 (1), 1-8, 2017
The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers
SF Lumley, J Wei, D O’Donnell, NE Stoesser, PC Matthews, A Howarth, ...
MedRxiv, 2020
The human short-chain dehydrogenase/reductase (SDR) superfamily: a bioinformatics summary
JE Bray, BD Marsden, U Oppermann
Chemico-biological interactions 178 (1-3), 99-109, 2009
The treatment of Wilms' tumour: results of the United Kingdom Children's cancer study group (UKCCSG) second Wilms' tumour study
C Mitchell, PM Jones, A Kelsey, GM Vujanic, B Marsden, R Shannon, ...
British journal of cancer 83 (5), 602-608, 2000
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases
NR Rose, ECY Woon, A Tumber, LJ Walport, R Chowdhury, XS Li, ...
Journal of medicinal chemistry 55 (14), 6639-6643, 2012
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