| Transcription control by the ENL YEATS domain in acute leukaemia MA Erb, TG Scott, BE Li, H Xie, J Paulk, HS Seo, A Souza, JM Roberts, ... Nature 543 (7644), 270-274, 2017 | 297 | 2017 |
| Degradation of the BAF complex factor BRD9 by heterobifunctional ligands D Remillard, DL Buckley, J Paulk, GL Brien, M Sonnett, HS Seo, ... Angewandte Chemie International Edition 56 (21), 5738-5743, 2017 | 291 | 2017 |
| Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands LN Gechijian, DL Buckley, MA Lawlor, JM Reyes, J Paulk, CJ Ott, ... Nature chemical biology 14 (4), 405-412, 2018 | 213 | 2018 |
| Structure-guided development of a potent and selective non-covalent active-site inhibitor of USP7 I Lamberto, X Liu, HS Seo, NJ Schauer, RE Iacob, W Hu, D Das, ... Cell chemical biology 24 (12), 1490-1500. e11, 2017 | 159 | 2017 |
| A fence-like coat for the nuclear pore membrane EW Debler, Y Ma, HS Seo, KC Hsia, TR Noriega, G Blobel, A Hoelz Molecular cell 32 (6), 815-826, 2008 | 140 | 2008 |
| Design and characterization of bivalent BET inhibitors M Tanaka, JM Roberts, HS Seo, A Souza, J Paulk, TG Scott, SL DeAngelo, ... Nature chemical biology 12 (12), 1089-1096, 2016 | 139 | 2016 |
| Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells S Kozono, YM Lin, HS Seo, B Pinch, X Lian, C Qiu, MK Herbert, CH Chen, ... Nature communications 9 (1), 3069, 2018 | 136 | 2018 |
| Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1 Y Ren, HS Seo, G Blobel, A Hoelz Proceedings of the National Academy of Sciences 107 (23), 10406-10411, 2010 | 119 | 2010 |
| Inhibition of USP10 induces degradation of oncogenic FLT3 EL Weisberg, NJ Schauer, J Yang, I Lamberto, L Doherty, S Bhatt, ... Nature chemical biology 13 (12), 1207-1215, 2017 | 111 | 2017 |
| MELK is not necessary for the proliferation of basal-like breast cancer cells HT Huang, HS Seo, T Zhang, Y Wang, B Jiang, Q Li, DL Buckley, B Nabet, ... Elife 6, e26693, 2017 | 103 | 2017 |
| EF-G-dependent GTPase on the ribosome. Conformational change and fusidic acid inhibition HS Seo, S Abedin, D Kamp, DN Wilson, KH Nierhaus, BS Cooperman Biochemistry 45 (8), 2504-2514, 2006 | 92 | 2006 |
| Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo C Dubiella, BJ Pinch, K Koikawa, D Zaidman, E Poon, TD Manz, B Nabet, ... Nature chemical biology 17 (9), 954-963, 2021 | 91 | 2021 |
| Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex HS Seo, Y Ma, EW Debler, D Wacker, S Kutik, G Blobel, A Hoelz Proceedings of the National Academy of Sciences 106 (34), 14281-14286, 2009 | 88 | 2009 |
| Recurrent SMARCB1 mutations reveal a nucleosome acidic patch interaction site that potentiates mSWI/SNF complex chromatin remodeling AM Valencia, CK Collings, HT Dao, RS Pierre, YC Cheng, J Huang, ... Cell 179 (6), 1342-1356. e23, 2019 | 85 | 2019 |
| Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1• Nup98) B Quan, HS Seo, G Blobel, Y Ren Proceedings of the National Academy of Sciences 111 (25), 9127-9132, 2014 | 74 | 2014 |
| Structural and functional consequences of the STAT5BN642H driver mutation ED de Araujo, F Erdogan, HA Neubauer, D Meneksedag-Erol, ... Nature communications 10 (1), 2517, 2019 | 72 | 2019 |
| An aluminum hydroxide: CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice E Nanishi, F Borriello, TR O’Meara, ME McGrath, Y Saito, RE Haupt, ... Science translational medicine 14 (629), eabj5305, 2021 | 70 | 2021 |
| Identification of a potent and selective covalent Pin1 inhibitor BJ Pinch, ZM Doctor, B Nabet, CM Browne, HS Seo, ML Mohardt, ... Nature chemical biology 16 (9), 979-987, 2020 | 58 | 2020 |
| Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex K Yoshida, HS Seo, EW Debler, G Blobel, A Hoelz Proceedings of the National Academy of Sciences 108 (40), 16571-16576, 2011 | 58 | 2011 |
| Lactate regulates cell cycle by remodelling the anaphase promoting complex W Liu, Y Wang, LHM Bozi, PD Fischer, MP Jedrychowski, H Xiao, T Wu, ... Nature 616 (7958), 790-797, 2023 | 57 | 2023 |
