Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 962 | 2012 |
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 633 | 2014 |
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison, S Croul, S Mack, ... Nature genetics 41 (4), 465-472, 2009 | 495 | 2009 |
Clonal selection drives genetic divergence of metastatic medulloblastoma X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ... Nature 482 (7386), 529-533, 2012 | 482 | 2012 |
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ... Cell 153 (5), 1064-1079, 2013 | 434 | 2013 |
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples PA Northcott, DJH Shih, M Remke, YJ Cho, M Kool, C Hawkins, ... Acta neuropathologica 123, 615-626, 2012 | 420 | 2012 |
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis V Ramaswamy, M Remke, E Bouffet, CC Faria, S Perreault, YJ Cho, ... The lancet oncology 14 (12), 1200-1207, 2013 | 399 | 2013 |
Cytogenetic prognostication within medulloblastoma subgroups DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ... Journal of clinical oncology 32 (9), 886-896, 2014 | 358 | 2014 |
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct PA Northcott, T Hielscher, A Dubuc, S Mack, D Shih, M Remke, ... Acta neuropathologica 122, 231-240, 2011 | 271 | 2011 |
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ... Acta neuropathologica 126, 917-929, 2013 | 199 | 2013 |
Molecular subgroups of medulloblastoma PA Northcott, AM Dubuc, S Pfister, MD Taylor Expert review of neurotherapeutics 12 (7), 871-884, 2012 | 196 | 2012 |
Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma AM Dubuc, M Remke, A Korshunov, PA Northcott, SH Zhan, ... Acta neuropathologica 125, 373-384, 2013 | 187 | 2013 |
MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma S Venkataraman, DK Birks, I Balakrishnan, I Alimova, PS Harris, PR Patel, ... Journal of Biological Chemistry 288 (3), 1918-1928, 2013 | 124 | 2013 |
Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells PS Harris, S Venkataraman, I Alimova, DK Birks, AM Donson, J Knipstein, ... BMC cancer 12, 1-13, 2012 | 103 | 2012 |
Medulloblastoma subgroups remain stable across primary and metastatic compartments X Wang, AM Dubuc, V Ramaswamy, S Mack, DMA Gendoo, M Remke, ... Acta neuropathologica 129, 449-457, 2015 | 100 | 2015 |
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics X Huang, AM Dubuc, R Hashizume, J Berg, Y He, J Wang, C Chiang, ... Genes & development 26 (16), 1780-1796, 2012 | 94 | 2012 |
Targeting the enhancer of zeste homologue 2 in medulloblastoma I Alimova, S Venkataraman, P Harris, VE Marquez, PA Northcott, A Dubuc, ... International journal of cancer 131 (8), 1800-1809, 2012 | 93 | 2012 |
Differential expression of microRNA species in organs of hibernating ground squirrels: a role in translational suppression during torpor A Dubuc, KB Storey Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1779 (10 …, 2008 | 93 | 2008 |
The genetics of pediatric brain tumors AM Dubuc, PA Northcott, S Mack, H Witt, S Pfister, MD Taylor Current neurology and neuroscience reports 10, 215-223, 2010 | 91 | 2010 |
The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis DT Vo, D Subramaniam, M Remke, TL Burton, PJ Uren, JA Gelfond, ... The American journal of pathology 181 (5), 1762-1772, 2012 | 87 | 2012 |