Genetic and epigenetic fine mapping of causal autoimmune disease variants KKH Farh, A Marson, J Zhu, M Kleinewietfeld, WJ Housley, S Beik, ... Nature 518 (7539), 337-343, 2015 | 1927 | 2015 |
Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP) EL Van Nostrand, GA Pratt, AA Shishkin, C Gelboin-Burkhart, MY Fang, ... Nature methods 13 (6), 508-514, 2016 | 1219 | 2016 |
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome JM Engreitz, A Pandya-Jones, P McDonel, A Shishkin, K Sirokman, ... Science 341 (6147), 1237973, 2013 | 1100 | 2013 |
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3 CA McHugh, CK Chen, A Chow, CF Surka, C Tran, P McDonel, ... Nature 521 (7551), 232-236, 2015 | 1098 | 2015 |
Higher-order inter-chromosomal hubs shape 3D genome organization in the nucleus SA Quinodoz, N Ollikainen, B Tabak, A Palla, JM Schmidt, E Detmar, ... Cell 174 (3), 744-757. e24, 2018 | 733 | 2018 |
High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis S Schwartz, SD Agarwala, MR Mumbach, M Jovanovic, P Mertins, ... Cell 155 (6), 1409-1421, 2013 | 639 | 2013 |
RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites JM Engreitz, K Sirokman, P McDonel, AA Shishkin, C Surka, P Russell, ... Cell 159 (1), 188-199, 2014 | 500 | 2014 |
Transcriptional and epigenetic dynamics during specification of human embryonic stem cells CA Gifford, MJ Ziller, H Gu, C Trapnell, J Donaghey, A Tsankov, ... Cell 153 (5), 1149-1163, 2013 | 484 | 2013 |
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 458 | 2010 |
Simultaneous generation of many RNA-seq libraries in a single reaction AA Shishkin, G Giannoukos, A Kucukural, D Ciulla, M Busby, C Surka, ... Nature methods 12 (4), 323-325, 2015 | 268 | 2015 |
Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs J Chen, AA Shishkin, X Zhu, S Kadri, I Maza, M Guttman, JH Hanna, ... Genome biology 17, 1-17, 2016 | 154 | 2016 |
Large-scale expansions of Friedreich's ataxia GAA repeats in yeast AA Shishkin, I Voineagu, R Matera, N Cherng, BT Chernet, ... Molecular cell 35 (1), 82-92, 2009 | 141 | 2009 |
Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility I Voineagu, CF Surka, AA Shishkin, MM Krasilnikova, SM Mirkin Nature structural & molecular biology 16 (2), 226-228, 2009 | 127 | 2009 |
Massively multiplexed RNA sequencing AA Shishkin, M Guttman, CF Surka, ES Lander US Patent 10,612,088, 2020 | 119 | 2020 |
Genome rearrangements caused by interstitial telomeric sequences in yeast AY Aksenova, PW Greenwell, M Dominska, AA Shishkin, JC Kim, ... Proceedings of the National Academy of Sciences 110 (49), 19866-19871, 2013 | 92 | 2013 |
Role of DNA polymerases in repeat-mediated genome instability KA Shah, AA Shishkin, I Voineagu, YI Pavlov, PV Shcherbakova, ... Cell reports 2 (5), 1088-1095, 2012 | 73 | 2012 |
Pooled CRISPR screens with imaging on microraft arrays reveals stress granule-regulatory factors EC Wheeler, AQ Vu, JM Einstein, M DiSalvo, N Ahmed, EL Van Nostrand, ... Nature methods 17 (6), 636-642, 2020 | 66 | 2020 |
Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells Y Zhang, AA Shishkin, Y Nishida, D Marcinkowski-Desmond, N Saini, ... Molecular cell 48 (2), 254-265, 2012 | 66 | 2012 |
Targeting transcription factor NFκB: comparative analysis of proteasome and IKK inhibitors AV Gasparian, OA Guryanova, DV Chebotaev, AA Shishkin, ... Cell Cycle 8 (10), 1559-1566, 2009 | 58 | 2009 |
Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast N Cherng, AA Shishkin, LI Schlager, RH Tuck, L Sloan, R Matera, ... Proceedings of the National Academy of Sciences 108 (7), 2843-2848, 2011 | 53 | 2011 |