Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance Y Zhang, W Yan, MA Collins, F Bednar, S Rakshit, BR Zetter, BZ Stanger, ... Cancer research 73 (20), 6359-6374, 2013 | 251 | 2013 |
Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo I Chung, G Han, M Seshadri, BM Gillard, W Yu, BA Foster, DL Trump, ... Cancer research 69 (3), 967-975, 2009 | 241 | 2009 |
Nrf2-dependent and-independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress. T Adachi, H Nakagawa, I Chung, Y Hagiya, K Hoshijima, N Noguchi, ... Journal of experimental therapeutics & oncology 6 (4), 2007 | 134 | 2007 |
Escalating progression of mental health disorders during the COVID-19 pandemic: Evidence from a nationwide survey LP Wong, H Alias, AA Md Fuzi, IS Omar, A Mohamad Nor, MP Tan, ... PloS one 16 (3), e0248916, 2021 | 133 | 2021 |
miR-135a contributes to paclitaxel resistance in tumor cells both in vitro and in vivo A Holleman, I Chung, RR Olsen, B Kwak, A Mizokami, N Saijo, ... Oncogene 30 (43), 4386-4398, 2011 | 132 | 2011 |
Rescue of paclitaxel sensitivity by repression of Prohibitin1 in drug-resistant cancer cells N Patel, SK Chatterjee, V Vrbanac, I Chung, CJ Mu, RR Olsen, ... Proceedings of the National Academy of Sciences 107 (6), 2503-2508, 2010 | 121 | 2010 |
Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells YS Wu, I Chung, WF Wong, A Masamune, MS Sim, CY Looi Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (2), 296-306, 2017 | 110 | 2017 |
Synthesis and anticancer activity of novel water soluble benzimidazole carbamates JE Cheong, M Zaffagni, I Chung, Y Xu, Y Wang, FE Jernigan, BR Zetter, ... European Journal of Medicinal Chemistry 144, 372-385, 2018 | 100 | 2018 |
Cancer-associated fibroblasts promote endometrial cancer growth via activation of interleukin-6/STAT-3/c-Myc pathway KS Subramaniam, IS Omar, SC Kwong, Z Mohamed, YL Woo, ... American journal of cancer research 6 (2), 200, 2016 | 93 | 2016 |
Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model J Banyard, I Chung, AM Wilson, G Vetter, A Le Béchec, DR Bielenberg, ... Scientific reports 3 (1), 3151, 2013 | 90 | 2013 |
Cancer-associated fibroblasts promote proliferation of endometrial cancer cells KS Subramaniam, ST Tham, Z Mohamed, YL Woo, NA Mat Adenan, ... PloS one 8 (7), e68923, 2013 | 90 | 2013 |
Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol I Chung, AR Karpf, JR Muindi, JM Conroy, NJ Nowak, CS Johnson, ... Journal of biological chemistry 282 (12), 8704-8714, 2007 | 88 | 2007 |
Differential antiproliferative effects of calcitriol on tumor-derived and matrigel-derived endothelial cells I Chung, MK Wong, G Flynn, W Yu, CS Johnson, DL Trump Cancer research 66 (17), 8565-8573, 2006 | 88 | 2006 |
Identification of genes regulating migration and invasion using a new model of metastatic prostate cancer J Banyard, I Chung, M Migliozzi, DT Phan, AM Wilson, BR Zetter, ... BMC cancer 14, 1-15, 2014 | 73 | 2014 |
Antiproliferative Activity of King Cobra (Ophiophagus hannah) Venom l‐Amino Acid Oxidase M Li Lee, I Chung, S Yee Fung, MS Kanthimathi, N Hong Tan Basic & clinical pharmacology & toxicology 114 (4), 336-343, 2014 | 60 | 2014 |
King cobra (Ophiophagus hannah) venom L-amino acid oxidase induces apoptosis in PC-3 cells and suppresses PC-3 solid tumor growth in a tumor xenograft mouse model ML Lee, SY Fung, I Chung, J Pailoor, SH Cheah, NH Tan International Journal of Medical Sciences 11 (6), 593, 2014 | 60 | 2014 |
Calcitriol (1, 25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis G Flynn, I Chung, WD Yu, M Romano, RA Modzelewski, CS Johnson, ... Oncology 70 (6), 447-457, 2007 | 53 | 2007 |
Metabolic role of fatty acid binding protein 7 in mediating triple-negative breast cancer cell death via PPAR-α signaling SC Kwong, AH Abd Jamil, A Rhodes, NA Taib, I Chung Journal of lipid research 60 (11), 1807-1817, 2019 | 47 | 2019 |
Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification YS Wu, CY Looi, KS Subramaniam, A Masamune, I Chung Oncotarget 7 (24), 36719, 2016 | 47 | 2016 |
Collagen induces a more proliferative, migratory and chemoresistant phenotype in head and neck cancer via DDR1 SL Lai, ML Tan, RJ Hollows, M Robinson, M Ibrahim, S Margielewska, ... Cancers 11 (11), 1766, 2019 | 46 | 2019 |