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Helena Kiefel
Helena Kiefel
Postdoctoral Fellow, Pathology, Stanford University
Verified email at stanford.edu
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Year
L1CAM: a major driver for tumor cell invasion and motility
H Kiefel, S Bondong, J Hazin, J Ridinger, U Schirmer, S Riedle, P Altevogt
Cell adhesion & migration 6 (4), 374-384, 2012
2242012
Up‐regulation of L1CAM is linked to loss of hormone receptors and E‐cadherin in aggressive subtypes of endometrial carcinomas
M Huszar, M Pfeifer, U Schirmer, H Kiefel, GE Konecny, A Ben‐Arie, ...
The Journal of pathology 220 (5), 551-561, 2010
1252010
Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity
S Riedle, H Kiefel, D Gast, S Bondong, S Wolterink, P Gutwein, P Altevogt
Biochem. J 420, 391-402, 2009
1232009
EMT-associated up-regulation of L1CAM provides insights into L1CAM-mediated integrin signalling and NF-κB activation
H Kiefel, S Bondong, M Pfeifer, U Schirmer, N Erbe-Hoffmann, H Schäfer, ...
Carcinogenesis, bgs198, 2012
962012
Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma
S Wolterink, G Moldenhauer, M Fogel, H Kiefel, M Pfeifer, S Lüttgau, ...
Cancer research 70 (6), 2504-2515, 2010
872010
L1CAM–integrin interaction induces constitutive NF-κB activation in pancreatic adenocarcinoma cells by enhancing IL-1β expression
H Kiefel, S Bondong, N Erbe-Hoffmann, J Hazin, S Riedle, J Wolf, ...
Oncogene 29 (34), 4766-4778, 2010
812010
Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma
H Schäfer, C Dieckmann, O Korniienko, G Moldenhauer, H Kiefel, ...
Cancer letters 319 (1), 66-82, 2012
802012
Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma
U Schirmer, K Doberstein, AK Rupp, NP Bretz, D Wuttig, H Kiefel, ...
Oncotarget 5 (2), 462-72, 2014
792014
Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-κB activation
S Bondong, H Kiefel, T Hielscher, AG Zeimet, R Zeillinger, D Pils, ...
Annals of oncology 23 (7), 1795-1802, 2012
792012
Linking L1CAM-mediated signaling to NF-κB activation
H Kiefel, M Pfeifer, S Bondong, J Hazin, P Altevogt
Trends in molecular medicine 17 (4), 178-187, 2011
762011
L1 cell adhesion molecule (L1CAM) as a pathogenetic factor in endometriosis
D Finas, M Huszar, A Agic, S Dogan, H Kiefel, S Riedle, D Gast, ...
Human reproduction 23 (5), 1053-1062, 2008
512008
Regulation of transcription factor E2F3a and its clinical relevance in ovarian cancer
D Reimer, M Hubalek, H Kiefel, S Riedle, S Skvortsov, M Erdel, ...
Oncogene 30 (38), 4038-4049, 2011
422011
The RGD integrin binding site in human L1-CAM is important for nuclear signaling
D Gast, S Riedle, H Kiefel, SS Müerköster, H Schäfer, MKE Schäfer, ...
Experimental cell research 314 (13), 2411-2418, 2008
412008
Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent
H Schäfer, C Geismann, C Heneweer, JH Egberts, O Korniienko, H Kiefel, ...
Carcinogenesis 33 (1), 84-93, 2012
312012
Angiogenic cytokines are antibody targets during graft-versus-leukemia reactions
M Piesche, VT Ho, H Kim, Y Nakazaki, M Nehil, NK Yaghi, D Kolodin, ...
Clinical Cancer Research 21 (5), 1010-1018, 2015
122015
Epidermal growth factor-mediated signaling in ovarian cancer and the role of miR-34a and 6p22 gene amplification-based E2F3a control.
D Reimer, H Kiefel, M Hubalek, M Erdel, N Concin, G Hofstetter, ...
ASCO Annual Meeting Proceedings 29 (15_suppl), e15535, 2011
2011
L1CAM–integrin interaction induces constitutive NF-jB activation in pancreatic adenocarcinoma cells by enhancing IL-1b expression
H Kiefel, S Bondong, N Erbe-Hoffmann, J Hazin, S Riedle, J Wolf, ...
Journal: ONC Disk used Despatch Date 29, 5, 2010
2010
L1CAM Function in Pancreatic Adenocarcinoma Cell Lines and Its Role in Constitutive NF-kappaB Activation
H Kiefel
2010
Abstract# 2163: Expression of full-length L1-CAM is required for tumor growth
H Kiefel, S Riedle, N Erbe-Hofmann, P Altevogt
Cancer Research 69 (9 Supplement), 2163-2163, 2009
2009
6p22-Genamplifikation und Methylierung des miR-34a Promoters, zwei EGF-R unabhängige Mechanismen der E2F3a-Regulation beim Ovarialkarzinom
D Reimer, H Kiefel, M Erdel, E Müller-Holzner, H Fiegl, C Marth, ...
Geburtshilfe und Frauenheilkunde 71 (04), A18, 0
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Articles 1–20