Krishna Chaitanya Bulusu
Krishna Chaitanya Bulusu
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
DeepSynergy: predicting anti-cancer drug synergy with Deep Learning
K Preuer, RPI Lewis, S Hochreiter, A Bender, KC Bulusu, G Klambauer
Bioinformatics 34 (9), 1538-1546, 2018
1092018
Modelling of compound combination effects and applications to efficacy and toxicity: state-of-the-art, challenges and perspectives
KC Bulusu, R Guha, DJ Mason, RPI Lewis, E Muratov, YK Motamedi, ...
Drug discovery today 21 (2), 225-238, 2016
1002016
Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo
CD Mohan, H Bharathkumar, KC Bulusu, V Pandey, S Rangappa, ...
Journal of Biological Chemistry 289 (49), 34296-34307, 2014
962014
canSAR: updated cancer research and drug discovery knowledgebase
KC Bulusu, JE Tym, EA Coker, AC Schierz, B Al-Lazikani
Nucleic acids research 42 (D1), D1040-D1047, 2014
822014
LBA51 Analysis of resistance mechanisms to osimertinib in patients with EGFR T790M advanced NSCLC from the AURA3 study
VA Papadimitrakopoulou, YL Wu, JY Han, MJ Ahn, SS Ramalingam, ...
Annals of Oncology 29 (suppl_8), mdy424. 064, 2018
702018
LBA51 Analysis of resistance mechanisms to osimertinib in patients with EGFR T790M advanced NSCLC from the AURA3 study
VA Papadimitrakopoulou, YL Wu, JY Han, MJ Ahn, SS Ramalingam, ...
Annals of Oncology 29 (suppl_8), mdy424. 064, 2018
702018
canSAR: an integrated cancer public translational research and drug discovery resource
MD Halling-Brown, KC Bulusu, M Patel, JE Tym, B Al-Lazikani
Nucleic acids research 40 (D1), D947-D956, 2012
692012
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 1-17, 2019
642019
Microwave-assisted synthesis, characterization and cytotoxic studies of novel estrogen receptor α ligands towards human breast cancer cells
H Bharathkumar, CD Mohan, H Ananda, JE Fuchs, F Li, S Rangappa, ...
Bioorganic & medicinal chemistry letters 25 (8), 1804-1807, 2015
252015
Novel adamantanyl-based thiadiazolyl pyrazoles targeting EGFR in triple-negative breast cancer
A Sebastian, V Pandey, CD Mohan, YT Chia, S Rangappa, J Mathai, ...
ACS omega 1 (6), 1412-1424, 2016
242016
Orthologue chemical space and its influence on target prediction
LH Mervin, KC Bulusu, L Kalash, AM Afzal, F Svensson, MA Firth, I Barrett, ...
Bioinformatics 34 (1), 72-79, 2018
202018
A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2
NC Anilkumar, MS Sundaram, CD Mohan, S Rangappa, KC Bulusu, ...
PLoS One 10 (7), e0131896, 2015
192015
Early clearance of plasma EGFR mutations as a predictor of response to osimertinib and comparator EGFR-TKIs in the FLAURA trial.
C Zhou, F Imamura, Y Cheng, I Okamoto, BC Cho, MC Lin, M Majem, ...
Journal of Clinical Oncology 37 (15_suppl), 9020-9020, 2019
162019
A cancer pharmacogenomic screen powering crowd-sourced advancement of drug combination prediction
MP Menden, D Wang, Y Guan, MJ Mason, B Szalai, KC Bulusu, T Yu, ...
BioRxiv, 200451, 2018
152018
Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies
D Módos, KC Bulusu, D Fazekas, J Kubisch, J Brooks, I Marczell, ...
NPJ systems biology and applications 3 (1), 1-13, 2017
122017
A cancer pharmacogenomic screen powering crowd-sourced advancement of drug combination prediction. bioRxiv
MP Menden, D Wang, Y Guan, M Mason, B Szalai, KC Bulusu, T Yu, ...
62018
Community assessment of cancer drug combination screens identifies strategies for synergy prediction
MP Menden, D Wang, Y Guan, M Mason, B Szalai, KC Bulusu, T Yu, ...
bioRxiv, 200451, 2017
62017
MOLPRINT 2D-based identification and synthesis of novel chromene based small molecules that target PLA2: validation through chemo-and bioinformatics approaches
HK Keerthy, HK Vivek, H Bharathkumar, S Rangappa, KC Bulusu, ...
RSC advances 5 (109), 89797-89808, 2015
42015
Development of a novel azaspirane that targets the JAK-STAT pathway in hepatocellular carcinoma in vitro and in vivo
CD Mohan, H Bharathkumar, KC Bulusu, V Pandey, S Rangappa, ...
Journal of Biological Chemistry, jbc. M114. 601104, 2014
42014
Analysis of Differential Efficacy and Affinity of GABAA (α1/α2) Selective Modulators
QU Ain, RM Owen, K Omoto, R Torella, KC Bulusu, DC Pryde, RC Glen, ...
Molecular Pharmaceutics 13 (11), 4001-4012, 2016
32016
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