Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice LA Becker, B Huang, G Bieri, R Ma, DA Knowles, P Jafar-Nejad, ... Nature 544 (7650), 367-371, 2017 | 516 | 2017 |
CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity NJ Kramer, MS Haney, DW Morgens, A Jovičić, J Couthouis, A Li, J Ousey, ... Nature genetics 50 (4), 603-612, 2018 | 213 | 2018 |
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons G Bieri, M Brahic, L Bousset, J Couthouis, NJ Kramer, R Ma, L Nakayama, ... Acta neuropathologica 137, 961-980, 2019 | 176 | 2019 |
Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis CH Chuang, PG Greenside, ZN Rogers, JJ Brady, D Yang, RK Ma, ... Nature medicine 23 (3), 291-300, 2017 | 152 | 2017 |
Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity IP Winters, SH Chiou, NK Paulk, CD McFarland, PV Lalgudi, RK Ma, ... Nature communications 8 (1), 2053, 2017 | 97 | 2017 |
An LKB1–SIK axis suppresses lung tumor growth and controls differentiation CW Murray, JJ Brady, MK Tsai, C Li, IP Winters, R Tang, L Andrejka, ... Cancer discovery 9 (11), 1590-1605, 2019 | 76 | 2019 |
BLIMP1 induces transient metastatic heterogeneity in pancreatic cancer SH Chiou, VI Risca, GX Wang, D Yang, BM Grüner, AS Kathiria, RK Ma, ... Cancer discovery 7 (10), 1184-1199, 2017 | 57 | 2017 |
Tumor suppressor activity of Selenbp1, a direct Nkx2-1 target, in lung adenocarcinoma DR Caswell, CH Chuang, RK Ma, IP Winters, EL Snyder, MM Winslow Molecular Cancer Research 16 (11), 1737-1749, 2018 | 35 | 2018 |
Hotspots of aberrant enhancer activity in fibrolamellar carcinoma reveal candidate oncogenic pathways and therapeutic vulnerabilities TA Dinh, R Sritharan, FD Smith, AB Francisco, RK Ma, RP Bunaciu, ... Cell reports 31 (2), 2020 | 24 | 2020 |
A framework for fibrolamellar carcinoma research and clinical trials TA Dinh, AF Utria, KC Barry, R Ma, GK Abou-Alfa, JD Gordan, EM Jaffee, ... Nature reviews Gastroenterology & hepatology 19 (5), 328-342, 2022 | 21 | 2022 |
DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling SS Kim, I Kycia, M Karski, RK Ma, EA Bordt, J Kwan, A Karki, E Winter, ... Plos one 17 (2), e0263829, 2022 | 8 | 2022 |
DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma RK Ma, PY Tsai, AR Farghli, A Shumway, M Kanke, JD Gordan, TS Gujral, ... Plos Genetics 20 (3), e1011216, 2024 | | 2024 |
Functional Examination of Long Noncoding RNAs and RNA Therapy in Fibrolamellar Carcinoma RKY Ma Cornell University, 2023 | | 2023 |
Defining the regulatory effects of candidate oncogenic non-coding RNA LINC00473 in fibrolamellar carcinoma RK Ma, M Kanke, K Vakili, P Sethupathy Cancer Research 82 (12_Supplement), 1557-1557, 2022 | | 2022 |