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Jonathan P. McMullen
Jonathan P. McMullen
Verified email at merck.com
Title
Cited by
Cited by
Year
Deciding whether to go with the flow: evaluating the merits of flow reactors for synthesis
RL Hartman, JP McMullen, KF Jensen
Angewandte Chemie International Edition 50 (33), 7502-7519, 2011
10952011
Integrated microreactors for reaction automation: new approaches to reaction development
JP McMullen, KF Jensen
Annual review of analytical chemistry 3, 19-42, 2010
4232010
An integrated microreactor system for self‐optimization of a heck reaction: From micro‐to mesoscale flow systems
JP McMullen, MT Stone, SL Buchwald, KF Jensen
Angewandte Chemie 39 (122), 7230-7234, 2010
2622010
Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation
T Noël, JR Naber, RL Hartman, JP McMullen, KF Jensen, SL Buchwald
Chemical Science 2 (2), 287-290, 2011
2402011
Rapid determination of reaction kinetics with an automated microfluidic system
JP McMullen, KF Jensen
Organic Process Research & Development 15 (2), 398-407, 2011
1972011
An automated microfluidic system for online optimization in chemical synthesis
JP McMullen, KF Jensen
Organic process research & development 14 (5), 1169-1176, 2010
1682010
Pro und kontra Strömungsreaktoren in der Synthese
RL Hartman, JP McMullen, KF Jensen
Angewandte Chemie 123 (33), 7642-7661, 2011
1302011
Development of an automated microfluidic reaction platform for multidimensional screening: reaction discovery employing bicyclo [3.2. 1] octanoid scaffolds
JR Goodell, JP McMullen, N Zaborenko, JR Maloney, CX Ho, KF Jensen, ...
The Journal of organic chemistry 74 (16), 6169-6180, 2009
1252009
Photon Equivalents as a Parameter for Scaling Photoredox Reactions in Flow: Translation of Photocatalytic C− N Cross‐Coupling from Lab Scale to Multikilogram Scale
EB Corcoran, JP McMullen, F Lévesque, MK Wismer, JR Naber
Angewandte Chemie International Edition 59 (29), 11964-11968, 2020
922020
Manufacturing process development for belzutifan, part 2: a continuous flow visible-light-induced benzylic bromination
C Bottecchia, F Levesque, JP McMullen, Y Ji, M Reibarkh, F Peng, L Tan, ...
Organic Process Research & Development 26 (3), 516-524, 2021
522021
Using flow to outpace fast proton transfer in an organometallic reaction for the manufacture of verubecestat (MK-8931)
DA Thaisrivongs, JR Naber, JP McMullen
Organic Process Research & Development 20 (11), 1997-2004, 2016
392016
Advancing flow chemistry portability: a simplified approach to scaling up flow chemistry
F Lévesque, NJ Rogus, G Spencer, P Grigorov, JP McMullen, ...
Organic Process Research & Development 22 (8), 1015-1021, 2018
382018
Multidimensional dynamic experiments for data-rich process development of reactions in flow
BM Wyvratt, JP McMullen, ST Grosser
Reaction Chemistry & Engineering 4 (9), 1637-1645, 2019
322019
Studies Toward the Scaling of Gas‐Liquid Photocycloadditions
EB Corcoran, F Lévesque, JP McMullen, JR Naber
ChemPhotoChem 2 (10), 931-937, 2018
252018
Benzylic photobromination for the synthesis of belzutifan: elucidation of reaction mechanisms using in situ LED-NMR
Y Ji, C Bottecchia, F Lévesque, K Narsimhan, D Lehnherr, JP McMullen, ...
The Journal of Organic Chemistry 87 (4), 2055-2062, 2021
222021
Development and scale-up of a continuous reaction for production of an active pharmaceutical ingredient intermediate
JP McMullen, CH Marton, BD Sherry, G Spencer, J Kukura, NS Eyke
Organic Process Research & Development 22 (9), 1208-1213, 2018
222018
Manufacturing process development for belzutifan, part 6: Ensuring scalability for a deoxyfluorination reaction
M Pirnot, K Stone, TJ Wright, DJ Lamberto, J Schoell, Y Lam, K Zawatzky, ...
Organic Process Research & Development 26 (3), 551-559, 2021
202021
Constrained version of the dynamic response surface methodology for modeling pharmaceutical reactions
Y Dong, C Georgakis, J Mustakis, JM Hawkins, L Han, K Wang, ...
Industrial & Engineering Chemistry Research 58 (30), 13611-13621, 2019
182019
Development of a commercial manufacturing route to 2-fluoroadenine, the key unnatural nucleobase of islatravir
CM Hong, Y Xu, JYL Chung, DM Schultz, M Weisel, RJ Varsolona, ...
Organic Process Research & Development 25 (3), 395-404, 2020
172020
One-step synthesis of 2-fluoroadenine using hydrogen fluoride pyridine in a continuous flow operation
N Salehi Marzijarani, DR Snead, JP McMullen, F Lévesque, M Weisel, ...
Organic Process Research & Development 23 (8), 1522-1528, 2019
162019
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