Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis K van Veldhoven, S Polidoro, L Baglietto, G Severi, C Sacerdote, ... Clinical epigenetics 7, 1-12, 2015 | 119 | 2015 |
Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity K Lubecka, L Kurzava, K Flower, H Buvala, H Zhang, D Teegarden, ... Carcinogenesis 37 (7), 656-668, 2016 | 93 | 2016 |
Platinum-based chemotherapy induces methylation changes in blood DNA associated with overall survival in patients with ovarian cancer JM Flanagan, A Wilson, C Koo, N Masrour, J Gallon, E Loomis, K Flower, ... Clinical Cancer Research 23 (9), 2213-2222, 2017 | 73 | 2017 |
Dynamic chromatin environment of key lytic cycle regulatory regions of the Epstein-Barr virus genome S Ramasubramanyan, K Osborn, K Flower, AJ Sinclair Journal of virology 86 (3), 1809-1819, 2012 | 68 | 2012 |
Clinical use of programmed cell death-1 and its ligand expression as discriminatory and predictive markers in ovarian cancer J Chatterjee, W Dai, NHA Aziz, PY Teo, J Wahba, DL Phelps, CJ Maine, ... Clinical Cancer Research 23 (13), 3453-3460, 2017 | 65 | 2017 |
Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor K Flower, D Thomas, J Heather, S Ramasubramanyan, S Jones, ... PloS one 6 (10), e25922, 2011 | 57 | 2011 |
Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women SS Oltra, M Peña-Chilet, V Vidal-Tomas, K Flower, MT Martinez, E Alonso, ... Scientific reports 8 (1), 14373, 2018 | 52 | 2018 |
The Epstein–Barr virus lytic cycle activator Zta interacts with methylated ZRE in the promoter of host target gene egr1 J Heather, K Flower, S Isaac, AJ Sinclair Journal of general virology 90 (6), 1450-1454, 2009 | 42 | 2009 |
Genome-wide analyses of Zta binding to the Epstein-Barr virus genome reveals interactions in both early and late lytic cycles and an epigenetic switch leading to an altered … S Ramasubramanyan, A Kanhere, K Osborn, K Flower, RG Jenner, ... Journal of virology 86 (23), 12494-12502, 2012 | 40 | 2012 |
Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues NS Shenker, KJ Flower, CS Wilhelm-Benartzi, W Dai, E Bell, E Gore, ... BMC cancer 15, 1-12, 2015 | 26 | 2015 |
Methylation of MYLK3 gene promoter region: a biomarker to stratify surgical care in ovarian cancer in a multicentre study DL Phelps, JV Borley, KJ Flower, R Dina, S Darb-Esfahani, I Braicu, ... British journal of cancer 116 (10), 1287-1293, 2017 | 25 | 2017 |
Stilbenoid‐mediated epigenetic activation of semaphorin 3A in breast cancer cells involves changes in dynamic interactions of DNA with DNMT3A and NF1C transcription factor M Beetch, K Lubecka, K Shen, K Flower, S Harandi‐Zadeh, M Suderman, ... Molecular nutrition & food research 63 (19), 1801386, 2019 | 22 | 2019 |
Atypical bZIP domain of viral transcription factor contributes to stability of dimer formation and transcriptional function C Schelcher, S Al Mehairi, E Verrall, Q Hope, K Flower, B Bromley, ... Journal of virology 81 (13), 7149-7155, 2007 | 22 | 2007 |
Acceleration in the DNA methylation age in breast cancer tumours from very young women SS Oltra, M Peña-Chilet, K Flower, MT Martinez, E Alonso, O Burgues, ... Scientific Reports 9 (1), 14991, 2019 | 18 | 2019 |
DNA methylation profiling to assess pathogenicity of BRCA1 unclassified variants in breast cancer KJ Flower, NS Shenker, M El-Bahrawy, DE Goldgar, MT Parsons, ... Epigenetics 10 (12), 1121-1132, 2015 | 17 | 2015 |
Loci-specific differences in blood DNA methylation in HBV-negative populations at risk for hepatocellular carcinoma development K Lubecka, K Flower, M Beetch, J Qiu, L Kurzava, H Buvala, A Ruhayel, ... Epigenetics 13 (6), 605-626, 2018 | 15 | 2018 |
Mise-en-place: Learning across disciplines C Schlegel, K Flower, J Youssef, B Kaeser, R Kneebone International Journal of Gastronomy and Food Science 16, 100147, 2019 | 12 | 2019 |
Evaluation of a prediction protocol to identify potential targets of epigenetic reprogramming by the cancer associated Epstein Barr virus K Flower, E Hellen, MJ Newport, S Jones, AJ Sinclair PLoS One 5 (2), e9443, 2010 | 12 | 2010 |
Is there a role for epigenetic enhancement of immunomodulatory approaches to cancer treatment? KJ Flower, S Ghaem-Maghami, R Brown Current Cancer Drug Targets 18 (1), 5-15, 2018 | 6 | 2018 |
Cell-free circulating tumor DNA methylation in high-grade serous ovarian cancer KR Davis, KJ Flower, JV Borley, CSM Wilhelm-Benartzi, R Brown Cancer Research 76 (14_Supplement), 3154-3154, 2016 | 5 | 2016 |