Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression H Song, KK Mak, L Topol, K Yun, J Hu, L Garrett, Y Chen, O Park, ... Proceedings of the National Academy of Sciences 107 (4), 1431-1436, 2010 | 626 | 2010 |
Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow L Wang, JY Luo, B Li, XY Tian, LJ Chen, Y Huang, J Liu, D Deng, CW Lau, ... Nature 540 (7634), 579-582, 2016 | 534 | 2016 |
Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy KK Mak, HM Kronenberg, PT Chuang, S Mackem, Y Yang Oxford University Press for The Company of Biologists Limited 135 (11), 1947 …, 2008 | 336 | 2008 |
Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression KK Mak, Y Bi, C Wan, PT Chuang, T Clemens, M Young, Y Yang Developmental cell 14 (5), 674-688, 2008 | 238 | 2008 |
Wnt/β-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation KK Mak, MH Chen, TF Day, PT Chuang, Y Yang Oxford University Press for The Company of Biologists Limited 133 (18), 3695 …, 2006 | 229 | 2006 |
Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation Y Deng, J Lu, W Li, A Wu, X Zhang, W Tong, KK Ho, L Qin, H Song, ... Nature communications 9 (1), 4564, 2018 | 221 | 2018 |
Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression LH Chan, W Wang, W Yeung, Y Deng, P Yuan, KK Mak Oncogene 33 (40), 4857-4866, 2014 | 171 | 2014 |
Yap1 regulates multiple steps of chondrocyte differentiation during skeletal development and bone repair Y Deng, A Wu, P Li, G Li, L Qin, H Song, KK Mak Cell reports 14 (9), 2224-2237, 2016 | 155 | 2016 |
Epidermal growth factor as a biologic switch in hair growth cycle KKL Mak, SY Chan Journal of Biological Chemistry 278 (28), 26120-26126, 2003 | 125 | 2003 |
The Wnt/β-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation X Guo, KK Mak, MM Taketo, Y Yang PloS one 4 (6), e6067, 2009 | 109 | 2009 |
Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice RWC Wong, RWP Kwan, PHS Mak, KKL Mak, MH Sham, SY Chan Journal of Biological Chemistry 275 (24), 18297-18301, 2000 | 105 | 2000 |
Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice RWC Wong, RWP Kwan, PHS Mak, KKL Mak, MH Sham, SY Chan Journal of Biological Chemistry 275 (24), 18297-18301, 2000 | 105 | 2000 |
A novel miR-193a-5p-YY1-APC regulatory axis in human endometrioid endometrial adenocarcinoma Y Yang, L Zhou, L Lu, L Wang, X Li, P Jiang, LKY Chan, T Zhang, J Yu, ... Oncogene 32 (29), 3432-3442, 2013 | 97 | 2013 |
Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade W Tong, Y Zeng, DHK Chow, W Yeung, J Xu, Y Deng, S Chen, H Zhao, ... Annals of the rheumatic diseases 78 (4), 551-561, 2019 | 91 | 2019 |
β-Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells MJ Nemeth, KK Mak, Y Yang, DM Bodine Stem Cells 27 (5), 1109-1119, 2009 | 90 | 2009 |
Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers X Sun, Z Ren, Y Cun, C Zhao, X Huang, J Zhou, R Hu, X Su, L Ji, P Li, ... Nucleic acids research 48 (13), 7182-7196, 2020 | 49 | 2020 |
Functional role of Mst1/Mst2 in embryonic stem cell differentiation P Li, Y Chen, KK Mak, CK Wong, CC Wang, P Yuan PloS one 8 (11), e79867, 2013 | 49 | 2013 |
Tubule-specific Mst1/2 deficiency induces CKD via YAP and non-YAP mechanisms C Xu, L Wang, Y Zhang, W Li, J Li, Y Wang, C Meng, J Qin, ZH Zheng, ... Journal of the American Society of Nephrology 31 (5), 946-961, 2020 | 45 | 2020 |
Osteocalcin expressing cells from tendon sheaths in mice contribute to tendon repair by activating Hedgehog signaling Y Wang, X Zhang, H Huang, Y Xia, YF Yao, AFT Mak, PSH Yung, ... Elife 6, e30474, 2017 | 42 | 2017 |
Engineering multi-tissue units for regenerative medicine: bone-tendon-muscle units of the rotator cuff D Wang, X Zhang, S Huang, Y Liu, BS Fu, KK Mak, AM Blocki, PS Yung, ... Biomaterials 272, 120789, 2021 | 33 | 2021 |