Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site C Pargellis, L Tong, L Churchill, PF Cirillo, T Gilmore, AG Graham, ... Nature structural biology 9 (4), 268-272, 2002 | 1055 | 2002 |
Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate J Regan, S Breitfelder, P Cirillo, T Gilmore, AG Graham, E Hickey, B Klaus, ... Journal of medicinal chemistry 45 (14), 2994-3008, 2002 | 422 | 2002 |
Structure−Activity Relationships of the p38α MAP Kinase Inhibitor 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea … J Regan, A Capolino, PF Cirillo, T Gilmore, AG Graham, E Hickey, ... Journal of medicinal chemistry 46 (22), 4676-4686, 2003 | 167 | 2003 |
Aromatic heterocyclic compounds as antiinflammatory agents PF Cirillo, R Dinallo, JR Regan, PS Riska, AD Swinamer, Z Tan, ... US Patent 6,525,046, 2003 | 162 | 2003 |
Aromatic heterocyclic compound as antiinflammatory agents PF Cirillo, TA Gilmore, ER Hickey, JR Regan, LH Zhang US Patent 6,319,921, 2001 | 146 | 2001 |
The kinetics of binding to p38 MAP kinase by analogues of BIRB 796 J Regan, CA Pargellis, PF Cirillo, T Gilmore, ER Hickey, GW Peet, A Proto, ... Bioorganic & medicinal chemistry letters 13 (18), 3101-3104, 2003 | 126 | 2003 |
Recent progress in the chemistry of acylsilanes. A review PF Cirillo, JS Panek Organic preparations and procedures international 24 (5), 553-582, 1992 | 123 | 1992 |
A Highly Convergent Total Synthetic Route to Glycopeptides Carrying a High‐Mannose Core Pentasaccharide Domain N‐linked to a Natural Peptide Motif SJ Danishefsky, S Hu, PF Cirillo, M Eckhardt, PH Seeberger Chemistry–A European Journal 3 (10), 1617-1628, 1997 | 118 | 1997 |
Compounds useful as anti-inflammatory agents S Breitfelder, PF Cirillo, TA Gilmore, ER Hickey, JR Proudfoot, JR Regan, ... US Patent 6,358,945, 2002 | 98 | 2002 |
The non-diaryl heterocycle classes of p38 MAP kinase inhibitors PF Cirillo, C Pargellis, J Regan Current topics in medicinal chemistry 2 (9), 1021-1035, 2002 | 92 | 2002 |
Aromatic heterocyclic compounds and their use as anti-inflammatory agents JR Regan, PF Cirillo, ER Hickey, N Moss, CL Cywin, C Pargellis, ... US Patent 6,080,763, 2000 | 91 | 2000 |
A novel allosteric inhibitor of macrophage migration inhibitory factor (MIF) F Bai, OA Asojo, P Cirillo, M Ciustea, M Ledizet, PA Aristoff, L Leng, ... Journal of Biological Chemistry 287 (36), 30653-30663, 2012 | 78 | 2012 |
1, 4-Disubstituted benzo-fused urea compounds PF Cirillo, A Hammach, JR Regan US Patent 6,825,184, 2004 | 74 | 2004 |
. pi.-Facial selectivity in catalytic osmylation reactions of chiral C1-oxygenated allylic silanes JS Panek, PF Cirillo Journal of the American Chemical Society 112 (12), 4873-4878, 1990 | 74 | 1990 |
Compounds useful as anti-inflammatory agents S Breitfelder, PF Cirillo, JR Regan US Patent 6,608,052, 2003 | 63 | 2003 |
Compounds useful as anti-inflammatory agents S Breitfelder, PF Cirillo, MH Hao, ER Hickey, R Sharma, S Sun, ... US Patent 6,492,393, 2002 | 63 | 2002 |
Compounds useful as anti-inflammatory agents PF Cirillo, DR Goldberg, A Hammach, N Moss, JR Regan US Patent 6,852,717, 2005 | 61 | 2005 |
1, 4-benzofused urea compounds useful in treating cytokine mediated diseases PF Cirillo, A Hammach, JR Regan US Patent 7,041,669, 2006 | 54 | 2006 |
Cytokine inhibitors PF Cirillo, DA Gao, DR Goldberg, A Hammach, MH Hao, VM Kamhi, ... US Patent 7,078,419, 2006 | 53 | 2006 |
Diastereoselectivity in nucleophilic addition reactions to (. alpha.,. beta.-dialkoxyacyl) silanes: an operationally useful route to optically active 1, 2, 3-syn-triols PF Cirillo, JS Panek The Journal of Organic Chemistry 55 (25), 6071-6073, 1990 | 53 | 1990 |