| Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial I Satti, J Meyer, SA Harris, ZRM Thomas, K Griffiths, RD Antrobus, ... The Lancet Infectious diseases 14 (10), 939-946, 2014 | 211 | 2014 |
| IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival S Lunardi, NB Jamieson, SY Lim, KL Griffiths, M Carvalho-Gaspar, ... Oncotarget 5 (22), 11064, 2014 | 129 | 2014 |
| Improvement of BCG protective efficacy with a novel chimpanzee adenovirus and a modified vaccinia Ankara virus both expressing Ag85A E Stylianou, KL Griffiths, HC Poyntz, R Harrington-Kandt, MD Dicks, ... Vaccine 33 (48), 6800-6808, 2015 | 115 | 2015 |
| Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis L Monin, KL Griffiths, WY Lam, R Gopal, DD Kang, M Ahmed, ... The Journal of clinical investigation 125 (12), 4699-4713, 2015 | 109 | 2015 |
| Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy KL Griffiths, M Ahmed, S Das, R Gopal, W Horne, TD Connell, ... Nature communications 7 (1), 13894, 2016 | 108 | 2016 |
| Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge L Monin, KL Griffiths, S Slight, Y Lin, J Rangel-Moreno, SA Khader Mucosal immunology 8 (5), 1099-1109, 2015 | 107 | 2015 |
| Non-tuberculous mycobacteria have diverse effects on BCG efficacy against Mycobacterium tuberculosis HC Poyntz, E Stylianou, KL Griffiths, L Marsay, AM Checkley, H McShane Tuberculosis 94 (3), 226-237, 2014 | 97 | 2014 |
| Novel vaccine approaches for protection against intracellular pathogens KL Griffiths, SA Khader Current opinion in immunology 28, 58-63, 2014 | 65 | 2014 |
| Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery J Meyer, SA Harris, I Satti, ID Poulton, HC Poyntz, R Tanner, R Rowland, ... Vaccine 31 (7), 1026-1033, 2013 | 63 | 2013 |
| Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis R Domingo-Gonzalez, S Das, KL Griffiths, M Ahmed, M Bambouskova, ... JCI insight 2 (19), 2017 | 57 | 2017 |
| Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb) L Marsay, M Matsumiya, R Tanner, H Poyntz, KL Griffiths, E Stylianou, ... Tuberculosis 93 (5), 551-557, 2013 | 54 | 2013 |
| A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults AM Minassian, R Rowland, NER Beveridge, ID Poulton, I Satti, S Harris, ... BMJ open 1 (2), e000223, 2011 | 53 | 2011 |
| Splenic stromal niches support hematopoiesis of dendritic-like cells from precursors in bone marrow and spleen P Periasamy, JKH Tan, KL Griffiths, HC O'Neill Experimental hematology 37 (9), 1060-1071, 2009 | 52 | 2009 |
| Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A KL Griffiths, AA Pathan, AM Minassian, CR Sander, NER Beveridge, ... PloS one 6 (8), e23463, 2011 | 51 | 2011 |
| Identification of a novel antigen cross‐presenting cell type in spleen JKH Tan, BJC Quah, KL Griffiths, P Periasamy, YY Hey, HC O’Neill Journal of Cellular and Molecular Medicine 15 (5), 1189-1199, 2011 | 39 | 2011 |
| Roles for Treg expansion and HMGB1 signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A M Matsumiya, E Stylianou, K Griffiths, Z Lang, J Meyer, SA Harris, ... PLoS One 8 (7), e67922, 2013 | 37 | 2013 |
| Spleen as a site for hematopoiesis of a distinct antigen presenting cell type HC O'Neill, KL Griffiths, P Periasamy, RA Hinton, YY Hey, S Petvises, ... Stem Cells International 2011, 2011 | 36 | 2011 |
| Rationalized design of a mucosal vaccine protects against Mycobacterium tuberculosis challenge in mice M Ahmed, H Jiao, R Domingo-Gonzalez, S Das, KL Griffiths, ... Journal of Leucocyte Biology 101 (6), 1373-1381, 2017 | 30 | 2017 |
| Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice KL Griffiths, E Stylianou, HC Poyntz, GJ Betts, HA Fletcher, H McShane PLoS One 8 (10), e78312, 2013 | 25 | 2013 |
| Dendritic cells as immune regulators: the mouse model KL Griffiths, HC O’Neill Journal of cellular and molecular medicine 12 (5b), 1909-1914, 2008 | 24 | 2008 |
